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2023

Voelkl K, Gutiérrez-Ángel S, Keeling S, Koyuncu S, da Silva Padilha M, Feigenbutz D, Arzberger T, Vilchez D, Klein R & Dudanova I
Neuroprotective effects of hepatoma-derived growth factor in models of Huntington's disease.
Life science alliance, 2023 Nov, 6 (11)

Bartos LM, Kirchleitner SV, Kolabas ZI, Quach S, Beck A, Lorenz J, Blobner J, Mueller SA, Ulukaya S, Hoeher L, Horvath I, Wind-Mark K, Holzgreve A, Ruf VC, Gold L, Kunze LH, Kunte ST, Beumers P, Park HE, Antons M, Zatcepin A, Briel N, Hoermann L, Schaefer R, Messerer D, Bartenstein P, Riemenschneider MJ, Lindner S, Ziegler S, Herms J, Lichtenthaler SF, Ertürk A, Tonn JC, von Baumgarten L, Albert NL & Brendel M
Deciphering sources of PET signals in the tumor microenvironment of glioblastoma at cellular resolution.
Science advances, 2023 Oct 27, 9 (43) eadi8986

Eckhardt A, Drexler R, Schoof M, Struve N, Capper D, Jelgersma C, Onken J, Harter PN, Weber KJ, Divé I, Rothkamm K, Hoffer K, Klumpp L, Ganser K, Petersen C, Ricklefs F, Kriegs M & Schüller U
Mean global DNA methylation serves as independent prognostic marker in IDH wild type glioblastoma.
Neuro-oncology, 2023 Oct 11

Albert NL, Nelwan DV, Fleischmann DF, Quach S, von Rohr K, Kaiser L, Teske N, Unterrainer LM, Bartos LM, Ruf VC, Brendel M, Riemenschneider MJ, Wetzel C, Herms J, Rupprecht R, Thon N, Tonn JC, Belka C, Bartenstein P, von Baumgarten L, Niyazi M, Unterrainer M & Holzgreve A
Prognostic Value of TSPO PET Before Radiotherapy in Newly Diagnosed IDH-Wild-Type Glioblastoma.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2023 Oct, 64 (10) 1519-1525

Grosse L, Lieftüchter V, Vollmuth Y, Hoffmann F, Olivieri M, Reiter K, Tacke M, Heinen F, Borggraefe I, Osterman A, Forstner M, Hübner J, von Both U, Birzele L, Rohlfs M, Schomburg A, Böhmer MM, Ruf V, Cadar D, Muntau B, Pörtner K & Tappe D
First detected geographical cluster of BoDV-1 encephalitis from same small village in two children: therapeutic considerations and epidemiological implications.
Infection, 2023 Oct, 51 (5) 1383-1398

Weidner L, Lorenz J, Quach S, Braun FK, Rothhammer-Hampl T, Ammer LM, Vollmann-Zwerenz A, Bartos LM, Dekorsy FJ, Holzgreve A, Kirchleitner SV, Thon N, Greve T, Ruf V, Herms J, Bader S, Milenkovic VM, von Baumgarten L, Menevse AN, Hussein A, Sax J, Wetzel CH, Rupprecht R, Proescholdt M, Schmidt NO, Beckhove P, Hau P, Tonn JC, Bartenstein P, Brendel M, Albert NL & Riemenschneider MJ
Translocator protein (18kDA) (TSPO) marks mesenchymal glioblastoma cell populations characterized by elevated numbers of tumor-associated macrophages.
Acta neuropathologica communications, 2023 Sep 11, 11 (1) 147

Schließer P, Struebing FL, Northoff BH, Kurz A, Rémi J, Holdt L, Höglinger GU, Herms J & Koeglsperger T
Detection of a Parkinson's Disease-Specific MicroRNA Signature in Nasal and Oral Swabs.
Movement disorders : official journal of the Movement Disorder Society, 2023 Sep, 38 (9) 1706-1715

Harrer P, Mirza-Schreiber N, Mandel V, Roeber S, Stefani A, Naher S, Wagner M, Gieger C, Waldenberger M, Peters A, Högl B, Herms J, Schormair B, Zhao C, Winkelmann J & Oexle K
Epigenetic Association Analyses and Risk Prediction of RLS.
Movement disorders : official journal of the Movement Disorder Society, 2023 Aug, 38 (8) 1410-1418

Drexler R, Khatri R, Sauvigny T, Mohme M, Maire CL, Ryba A, Zghaibeh Y, Dührsen L, Salviano-Silva A, Lamszus K, Westphal M, Gempt J, Wefers AK, Neumann J, Bode H, Hausmann F, Huber TB, Bonn S, Jütten K, Delev D, Weber KJ, Harter PN, Onken J, Vajkoczy P, Capper D, Wiestler B, Weller M, Snijder B, Buck A, Weiss T, Keough MB, Ni L, Monje M, Silverbush D, Hovestadt V, Suvà ML, Krishna S, Hervey-Jumper SL, Schüller U, Heiland DH, Hänzelmann S & Ricklefs FL
Epigenetic neural glioblastoma enhances synaptic integration and predicts therapeutic vulnerability.
bioRxiv : the preprint server for biology, 2023 Aug 07

Pratsch K, Unemura C, Ito M, Lichtenthaler SF, Horiguchi N & Herms J
New Highly Selective BACE1 Inhibitors and Their Effects on Dendritic Spine Density In Vivo.
International journal of molecular sciences, 2023 Jul 31, 24 (15)

Haake M, Haack B, Schäfer T, Harter PN, Mattavelli G, Eiring P, Vashist N, Wedekink F, Genssler S, Fischer B, Dahlhoff J, Mokhtari F, Kuzkina A, Welters MJP, Benz TM, Sorger L, Thiemann V, Almanzar G, Selle M, Thein K, Späth J, Gonzalez MC, Reitinger C, Ipsen-Escobedo A, Wistuba-Hamprecht K, Eichler K, Filipski K, Zeiner PS, Beschorner R, Goedemans R, Gogolla FH, Hackl H, Rooswinkel RW, Thiem A, Roche PR, Joshi H, Pühringer D, Wöckel A, Diessner JE, Rüdiger M, Leo E, Cheng PF, Levesque MP, Goebeler M, Sauer M, Nimmerjahn F, Schuberth-Wagner C, von Felten S, Mittelbronn M, Mehling M, Beilhack A, van der Burg SH, Riedel A, Weide B, Dummer R & Wischhusen J
Tumor-derived GDF-15 blocks LFA-1 dependent T cell recruitment and suppresses responses to anti-PD-1 treatment.
Nature communications, 2023 Jul 20, 14 (1) 4253

Riemenschneider H, Simonetti F, Sheth U, Katona E, Roth S, Hutten S, Farny D, Michaelsen M, Nuscher B, Schmidt MK, Flatley A, Schepers A, Gruijs da Silva LA, Zhou Q, Klopstock T, Liesz A, Arzberger T, Herms J, Feederle R, Gendron TF, Dormann D & Edbauer D
Targeting the glycine-rich domain of TDP-43 with antibodies prevents its aggregation in vitro and reduces neurofilament levels in vivo.
Acta neuropathologica communications, 2023 Jul 11, 11 (1) 112

Kunze LH, Ruch F, Biechele G, Eckenweber F, Wind-Mark K, Dinkel L, Feyen P, Bartenstein P, Ziegler S, Paeger L, Tahirovic S, Herms J & Brendel M
Long-Term Pioglitazone Treatment Has No Significant Impact on Microglial Activation and Tau Pathology in P301S Mice.
International journal of molecular sciences, 2023 Jun 14, 24 (12)

Weller J, Katzendobler S, Niedermeyer S, Harter PN, Herms J, Trumm C, Niyazi M, Thon N, Tonn JC & Stoecklein VM
Treatment benefit in patients aged 80 years or older with biopsy-proven and non-resected glioblastoma is dependent on MGMT promoter methylation status.
Journal of neuro-oncology, 2023 Jun, 163 (2) 407-415

Hoffmann L, Coras R, Kobow K, López-Rivera JA, Lal D, Leu C, Najm I, Nürnberg P, Herms J, Harter PN, Bien CG, Kalbhenn T, Müller M, Pieper T, Hartlieb T, Kudernatsch M, Hamer H, Brandner S, Rössler K, Blümcke I & Jabari S
Ganglioglioma with adverse clinical outcome and atypical histopathological features were defined by alterations in PTPN11/KRAS/NF1 and other RAS-/MAP-Kinase pathway genes.
Acta neuropathologica, 2023 Jun, 145 (6) 815-827

Hoffmann L, Coras R, Kobow K, López-Rivera JA, Lal D, Leu C, Najm I, Nürnberg P, Herms J, Harter PN, Bien CG, Kalbhenn T, Müller M, Pieper T, Hartlieb T, Kudernatsch M, Hamer H, Brandner S, Rössler K, Blümcke I & Jabari S
Correction to: Ganglioglioma with adverse clinical outcome and atypical histopathological features were defined by alterations in PTPN11/KRAS/NF1 and other RAS-/MAP-Kinase pathway genes.
Acta neuropathologica, 2023 Jun, 145 (6) 851-855

Koeglsperger T, Rumpf SL, Schließer P, Struebing FL, Brendel M, Levin J, Trenkwalder C, Höglinger GU & Herms J
Neuropathology of incidental Lewy body & prodromal Parkinson's disease.
Molecular neurodegeneration, 2023 May 12, 18 (1) 32

Spitzer D, Khel MI, Pütz T, Zinke J, Jia X, Sommer K, Filipski K, Thorsen F, Freiman TM, Günther S, Plate KH, Harter PN, Liebner S, Reiss Y, Di Tacchio M, Guérit S & Devraj K
A flow cytometry-based protocol for syngenic isolation of neurovascular unit cells from mouse and human tissues.
Nature protocols, 2023 May, 18 (5) 1510-1542

Harter PN, Weber KJ & Ronellenfitsch MW
[Histological and molecular characteristics of tumours of the peripheral nervous system].
Pathologie (Heidelberg, Germany), 2023 May, 44 (3) 197-208

Burger MC, Forster MT, Romanski A, Straßheimer F, Macas J, Zeiner PS, Steidl E, Herkt S, Weber KJ, Schupp J, Lun JH, Strecker MI, Wlotzka K, Cakmak P, Opitz C, George R, Mildenberger IC, Nowakowska P, Zhang C, Röder J, Müller E, Ihrig K, Langen KJ, Rieger MA, Herrmann E, Bönig H, Harter PN, Reiss Y, Hattingen E, Rödel F, Plate KH, Tonn T, Senft C, Steinbach JP & Wels WS
Intracranial injection of NK cells engineered with a HER2-targeted chimeric antigen receptor in patients with recurrent glioblastoma.
Neuro-oncology, 2023 May 06

Valentino RR, Scotton WJ, Roemer SF, Lashley T, Heckman MG, Shoai M, Martinez-Carrasco A, Tamvaka N, Walton RL, Baker MC, Macpherson HL, Real R, Soto-Beasley AI, Mok K, Revesz T, Warner TT, Jaunmuktane Z, Boeve BF, Christopher EA, DeTure M, Duara R, Graff-Radford NR, Josephs KA, Knopman DS, Koga S, Murray ME, Lyons KE, Pahwa R, Parisi JE, Petersen RC, Whitwell J, Grinberg LT, Miller B, Schlereth A, Seeley WW, Spina S, Grossman M, Irwin DJ, Lee EB, Suh E, Trojanowski JQ, Van Deerlin VM, Wolk DA, Connors TR, Dooley PM, Frosch MP, Oakley DH, Aldecoa I, Balasa M, Gelpi E, Borrego-Écija S, de Eugenio Huélamo RM, Gascon-Bayarri J, Sánchez-Valle R, Sanz-Cartagena P, Piñol-Ripoll G, Molina-Porcel L, Bigio EH, Flanagan ME, Gefen T, Rogalski EJ, Weintraub S, Redding-Ochoa J, Chang K, Troncoso JC, Prokop S, Newell KL, Ghetti B, Jones M, Richardson A, Robinson AC, Roncaroli F, Snowden J, Allinson K, Green O, Rowe JB, Singh P, Beach TG, Serrano GE, Flowers XE, Goldman JE, Heaps AC, Leskinen SP, Teich AF, Black SE, Keith JL, Masellis M, Bodi I, King A, Sarraj SA, Troakes C, Halliday GM, Hodges JR, Kril JJ, Kwok JB, Piguet O, Gearing M, Arzberger T, Roeber S, Attems J, Morris CM, Thomas AJ, Evers BM, White CL, Mechawar N, Sieben AA, Cras PP, De Vil BB, De Deyn PPPP, Duyckaerts C, Le Ber I, Seihean D, Turbant-Leclere S, MacKenzie IR, McLean C, Cykowski MD, Ervin JF, Wang SJ, Graff C, Nennesmo I, Nagra RM, Riehl J, Kovacs GG, Giaccone G, Nacmias B, Neumann M, Ang LC, Finger EC, Blauwendraat C, Nalls MA, Singleton AB, Vitale D, Cunha C, Carvalho A, Wszolek ZK, Morris HR, Rademakers R, Hardy JA, Dickson DW, Rohrer JD & Ross OA
Creating the Pick's disease International Consortium: Association study of MAPT H2 haplotype with risk of Pick's disease.
medRxiv : the preprint server for health sciences, 2023 Apr 24

Teske N, Chiquillo-Domínguez M, Skrap B, Harter PN, Rejeski K, Blobner J, von Baumgarten L, Tonn JC, Kunz M, Thon N & Karschnia P
Shunt dependency in supratentorial intraventricular tumors depends on the extent of tumor resection.
Acta neurochirurgica, 2023 Apr, 165 (4) 1053-1064

Matosin N, Arloth J, Czamara D, Edmond KZ, Maitra M, Fröhlich AS, Martinelli S, Kaul D, Bartlett R, Curry AR, Gassen NC, Hafner K, Müller NS, Worf K, Rehawi G, Nagy C, Halldorsdottir T, Cruceanu C, Gagliardi M, Gerstner N, Ködel M, Murek V, Ziller MJ, Scarr E, Tao R, Jaffe AE, Arzberger T, Falkai P, Kleinmann JE, Weinberger DR, Mechawar N, Schmitt A, Dean B, Turecki G, Hyde TM & Binder EB
Associations of psychiatric disease and ageing with FKBP5 expression converge on superficial layer neurons of the neocortex.
Acta neuropathologica, 2023 Apr, 145 (4) 439-459

Friedauer L, Foerch C, Steinbach J, Hattingen E, Harter PN, Armbrust M, Urban H, Steidl E, Neuhaus E & von Brauchitsch S
The Acute Superficial Siderosis Syndrome - Clinical Entity, Imaging Findings, and Histopathology.
Cerebellum (London, England), 2023 Apr, 22 (2) 296-304

Tauber CV, Schwarz SC, Rösler TW, Arzberger T, Gentleman S, Windl O, Krumbiegel M, Reis A, Ruf VC, Herms J & Höglinger GU
Different MAPT haplotypes influence expression of total MAPT in postmortem brain tissue.
Acta neuropathologica communications, 2023 Mar 11, 11 (1) 40

Ballweg A, Klaus C, Vogler L, Katzdobler S, Wind K, Zatcepin A, Ziegler SI, Secgin B, Eckenweber F, Bohr B, Bernhardt A, Fietzek U, Rauchmann BS, Stoecklein S, Quach S, Beyer L, Scheifele M, Simmet M, Joseph E, Lindner S, Berg I, Koglin N, Mueller A, Stephens AW, Bartenstein P, Tonn JC, Albert NL, Kümpfel T, Kerschensteiner M, Perneczky R, Levin J, Paeger L, Herms J & Brendel M
[18F]F-DED PET imaging of reactive astrogliosis in neurodegenerative diseases: preclinical proof of concept and first-in-human data.
Journal of neuroinflammation, 2023 Mar 11, 20 (1) 68

Quach S, Schwartz C, Aumiller M, Foglar M, Schmutzer M, Katzendobler S, El Fahim M, Forbrig R, Bochmann K, Egensperger R, Sroka R, Stepp H, Rühm A & Thon N
Interstitial photodynamic therapy for newly diagnosed glioblastoma.
Journal of neuro-oncology, 2023 Mar, 162 (1) 217-223

Gnörich J, Reifschneider A, Wind K, Zatcepin A, Kunte ST, Beumers P, Bartos LM, Wiedemann T, Grosch M, Xiang X, Fard MK, Ruch F, Werner G, Koehler M, Slemann L, Hummel S, Briel N, Blume T, Shi Y, Biechele G, Beyer L, Eckenweber F, Scheifele M, Bartenstein P, Albert NL, Herms J, Tahirovic S, Haass C, Capell A, Ziegler S & Brendel M
Depletion and activation of microglia impact metabolic connectivity of the mouse brain.
Journal of neuroinflammation, 2023 Feb 24, 20 (1) 47

Drexler R, Schüller U, Eckhardt A, Filipski K, Hartung TI, Harter PN, Divé I, Forster MT, Czabanka M, Jelgersma C, Onken J, Vajkoczy P, Capper D, Siewert C, Sauvigny T, Lamszus K, Westphal M, Dührsen L & Ricklefs FL
DNA methylation subclasses predict the benefit from gross total tumor resection in IDH-wildtype glioblastoma patients.
Neuro-oncology, 2023 Feb 14, 25 (2) 315-325

Schweizer L, Seegerer P, Kim HY, Saitenmacher R, Muench A, Barnick L, Osterloh A, Dittmayer C, Jödicke R, Pehl D, Reinhardt A, Ruprecht K, Stenzel W, Wefers AK, Harter PN, Schüller U, Heppner FL, Alber M, Müller KR & Klauschen F
Analysing cerebrospinal fluid with explainable deep learning: From diagnostics to insights.
Neuropathology and applied neurobiology, 2023 Feb, 49 (1) e12866

Kiyose M, Herrmann E, Roesler J, Zeiner PS, Steinbach JP, Forster MT, Plate KH, Czabanka M, Vogl TJ, Hattingen E, Mittelbronn M, Breuer S, Harter PN & Bernatz S
MR imaging profile and histopathological characteristics of tumour vasculature, cell density and proliferation rate define two distinct growth patterns of human brain metastases from lung cancer.
Neuroradiology, 2023 Feb, 65 (2) 275-285

Quach S, Holzgreve A, Kaiser L, Unterrainer M, Dekorsy FJ, Nelwan DV, Bartos LM, Kirchleitner SV, Weller J, Weidner L, Niyazi M, Ruf VC, Herms J, Stöcklein S, Wetzel C, Riemenschneider MJ, V Baumgarten L, Thon N, Brendel M, Rupprecht R, Bartenstein P, Tonn JC & Albert NL
TSPO PET signal using [18F]GE180 is associated with survival in recurrent gliomas.
European journal of nuclear medicine and molecular imaging, 2023 Feb, 50 (3) 859-869

Pohl S, Dimitrova L, Grassow-Narlik M, Jöhrens K, Acker T, Dohmen H, Herms J, Dorostkar M, Hartmann C, Hasselblatt M, Neumann M, Reifenberger G, Felsberg J, Schüller U, Zoubaa S, Lorenz J, Rothhammer-Hampl T, Mauch-Mücke K & Riemenschneider MJ
Update on quality assurance in neuropathology: Summary of the round robin trials on TERT promoter mutation, H3-3A mutation, 1p/19q codeletion, and KIAA1549::BRAF fusion testing in Germany in 2020 and 2021.
Clinical neuropathology, 2023, 42 (3) 112-121

Vogler L, Ballweg A, Bohr B, Briel N, Wind K, Antons M, Kunze LH, Gnörich J, Lindner S, Gildehaus FJ, Baumann K, Bartenstein P, Boening G, Ziegler SI, Levin J, Zwergal A, Höglinger GU, Herms J & Brendel M
Assessment of synaptic loss in mouse models of β-amyloid and tau pathology using [18F]UCB-H PET imaging.
NeuroImage. Clinical, 2023, 39 103484

Gretser S, Weber KJ, Braun Y, Harter PN, Rolle U, McNally J & Gradhand E
Tissue Shrinkage of Resected Specimens in Hirschsprung's Disease: Why Pediatric Surgeons Think the Bowel Specimen was Longer Than Indicated in the Pathology Report.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society, 2023, 26 (3) 287-291

Li Z, Holzgreve A, Unterrainer LM, Ruf VC, Quach S, Bartos LM, Suchorska B, Niyazi M, Wenter V, Herms J, Bartenstein P, Tonn JC, Unterrainer M, Albert NL & Kaiser L
Combination of pre-treatment dynamic [18F]FET PET radiomics and conventional clinical parameters for the survival stratification in patients with IDH-wildtype glioblastoma.
European journal of nuclear medicine and molecular imaging, 2023 Jan, 50 (2) 535-545

Proestler E, Donzelli J, Nevermann S, Breitwieser K, Koch LF, Best T, Fauth M, Wickström M, Harter PN, Kogner P, Lavieu G, Larsson K & Saul MJ
The multiple functions of miR-574-5p in the neuroblastoma tumor microenvironment.
Frontiers in pharmacology, 2023, 14 1183720

Blobner J, Dengler L, Blobner S, Eberle C, Weller J, Teske N, Karschnia P, Rühlmann K, Heinrich K, Ziemann F, Greif PA, Jeremias I, Wuerstlein R, Hasselmann K, Dorostkar M, Harter PN, Quach S, Stoecklein V, Albert NL, Niyazi M, Tonn JC, Thon N, Christoph Westphalen B & von Baumgarten L
Significance of molecular diagnostics for therapeutic decision-making in recurrent glioma.
Neuro-oncology advances, 2023, 5 (1) vdad060

2022

Key J, Gispert S, Koornneef L, Sleddens-Linkels E, Kohli A, Torres-Odio S, Koepf G, Amr S, Reichlmeir M, Harter PN, West AP, Münch C, Baarends WM & Auburger G
CLPP Depletion Causes Diplotene Arrest; Underlying Testis Mitochondrial Dysfunction Occurs with Accumulation of Perrault Proteins ERAL1, PEO1, and HARS2.
Cells, 2022 Dec 22, 12 (1)

Dening Y, Straßl T, Ruf V, Dirscherl P, Chovsepian A, Stievenard A, Khairnar A, Schmidt F, Giesert F, Herms J, Levin J, Dieterich M, Falkai P, Weisenhorn DV, Wurst W, Giese A & Pan-Montojo F
Toxicity of extracellular alpha-synuclein is independent of intracellular alpha-synuclein.
Scientific reports, 2022 Dec 19, 12 (1) 21951

Liu I, Jiang L, Samuelsson ER, Marco Salas S, Beck A, Hack OA, Jeong D, Shaw ML, Englinger B, LaBelle J, Mire HM, Madlener S, Mayr L, Quezada MA, Trissal M, Panditharatna E, Ernst KJ, Vogelzang J, Gatesman TA, Halbert ME, Palova H, Pokorna P, Sterba J, Slaby O, Geyeregger R, Diaz A, Findlay IJ, Dun MD, Resnick A, Suvà ML, Jones DTW, Agnihotri S, Svedlund J, Koschmann C, Haberler C, Czech T, Slavc I, Cotter JA, Ligon KL, Alexandrescu S, Yung WKA, Arrillaga-Romany I, Gojo J, Monje M, Nilsson M & Filbin MG
The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location.
Nature genetics, 2022 Dec, 54 (12) 1881-1894

Spitzer D, Puetz T, Armbrust M, Dunst M, Macas J, Croll F, Plate KH, Reiss Y, Liebner S, Harter PN, Guérit S & Devraj K
Anti-osteopontin therapy leads to improved edema and infarct size in a murine model of ischemic stroke.
Scientific reports, 2022 Dec 03, 12 (1) 20925

Panditharatna E, Marques JG, Wang T, Trissal MC, Liu I, Jiang L, Beck A, Groves A, Dharia NV, Li D, Hoffman SE, Kugener G, Shaw ML, Mire HM, Hack OA, Dempster JM, Lareau C, Dai L, Sigua LH, Quezada MA, Stanton AJ, Wyatt M, Kalani Z, Goodale A, Vazquez F, Piccioni F, Doench JG, Root DE, Anastas JN, Jones KL, Conway AS, Stopka S, Regan MS, Liang Y, Seo HS, Song K, Bashyal P, Jerome WP, Mathewson ND, Dhe-Paganon S, Suvà ML, Carcaboso AM, Lavarino C, Mora J, Nguyen QD, Ligon KL, Shi Y, Agnihotri S, Agar NYR, Stegmaier K, Stiles CD, Monje M, Golub TR, Qi J & Filbin MG
BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma.
Cancer discovery, 2022 Dec 02, 12 (12) 2880-2905

Schöning JV, Flitsch J, Lüdecke DK, Fahlbusch R, Buchfelder M, Buslei R, Knappe UJ, Bergmann M, Schulz-Schaeffer WJ, Herms J, Glatzel M & Saeger W
Multiple tumorous lesions of the pituitary gland.
Hormones (Athens, Greece), 2022 Dec, 21 (4) 653-663

Felix M, Friedel D, Jayavelu AK, Filipski K, Reinhardt A, Warnken U, Stichel D, Schrimpf D, Korshunov A, Wang Y, Kessler T, Etminan N, Unterberg A, Herold-Mende C, Heikaus L, Sahm F, Wick W, Harter PN, von Deimling A & Reuss DE
HIP1R and vimentin immunohistochemistry predict 1p/19q status in IDH-mutant glioma.
Neuro-oncology, 2022 Dec 01, 24 (12) 2121-2132

Jurmeister P, Glöß S, Roller R, Leitheiser M, Schmid S, Mochmann LH, Payá Capilla E, Fritz R, Dittmayer C, Friedrich C, Thieme A, Keyl P, Jarosch A, Schallenberg S, Bläker H, Hoffmann I, Vollbrecht C, Lehmann A, Hummel M, Heim D, Haji M, Harter P, Englert B, Frank S, Hench J, Paulus W, Hasselblatt M, Hartmann W, Dohmen H, Keber U, Jank P, Denkert C, Stadelmann C, Bremmer F, Richter A, Wefers A, Ribbat-Idel J, Perner S, Idel C, Chiariotti L, Della Monica R, Marinelli A, Schüller U, Bockmayr M, Liu J, Lund VJ, Forster M, Lechner M, Lorenzo-Guerra SL, Hermsen M, Johann PD, Agaimy A, Seegerer P, Koch A, Heppner F, Pfister SM, Jones DTW, Sill M, von Deimling A, Snuderl M, Müller KR, Forgó E, Howitt BE, Mertins P, Klauschen F & Capper D
DNA methylation-based classification of sinonasal tumors.
Nature communications, 2022 Nov 28, 13 (1) 7148

Messerschmidt K, Barthel H, Brendel M, Scherlach C, Hoffmann KT, Rauchmann BS, Rullmann M, Marek K, Villemagne VL, Rumpf JJ, Saur D, Schroeter ML, Schildan A, Patt M, Beyer L, Song M, Palleis C, Katzdobler S, Fietzek UM, Respondek G, Scheifele M, Nitschmann A, Zach C, Barret O, Madonia J, Russell D, Stephens AW, Koglin N, Roeber S, Herms J, Bötzel K, Bartenstein P, Levin J, Seibyl JP, Höglinger G, Classen J, Sabri O & German Imaging Initiative for Tauopathies (GII4T)
18F-PI-2620 Tau PET Improves the Imaging Diagnosis of Progressive Supranuclear Palsy.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2022 Nov, 63 (11) 1754-1760

Weller J, Katzendobler S, Blobner J, Thiele F, Becker H, Quach S, Egensperger R, Niyazi M, Suchorska B, Thon N, Weller M & Tonn JC
Limited efficacy of temozolomide alone for astrocytoma, IDH-mutant, CNS WHO grades 2 or 3.
Journal of neuro-oncology, 2022 Oct, 160 (1) 149-158

Hopfner F, Tietz AK, Ruf VC, Ross OA, Koga S, Dickson D, Aguzzi A, Attems J, Beach T, Beller A, Cheshire WP, van Deerlin V, Desplats P, Deuschl G, Duyckaerts C, Ellinghaus D, Evsyukov V, Flanagan ME, Franke A, Frosch MP, Gearing M, Gelpi E, van Gerpen JA, Ghetti B, Glass JD, Grinberg LT, Halliday G, Helbig I, Höllerhage M, Huitinga I, Irwin DJ, Keene DC, Kovacs GG, Lee EB, Levin J, Martí MJ, Mackenzie I, McKeith I, Mclean C, Mollenhauer B, Neumann M, Newell KL, Pantelyat A, Pendziwiat M, Peters A, Molina Porcel L, Rabano A, Matěj R, Rajput A, Rajput A, Reimann R, Scott WK, Seeley W, Selvackadunco S, Simuni T, Stadelmann C, Svenningsson P, Thomas A, Trenkwalder C, Troakes C, Trojanowski JQ, Uitti RJ, White CL, Wszolek ZK, Xie T, Ximelis T, Yebenes J, Alzheimer's Disease Genetics Consortium, Müller U, Schellenberg GD, Herms J, Kuhlenbäumer G & Höglinger G
Common Variants Near ZIC1 and ZIC4 in Autopsy-Confirmed Multiple System Atrophy.
Movement disorders : official journal of the Movement Disorder Society, 2022 Oct, 37 (10) 2110-2121

Lukic MJ, Respondek G, Kurz C, Compta Y, Gelpi E, Ferguson LW, Rajput A, Troakes C, MDS-endorsed PSP study group, van Swieten JC, Giese A, Roeber S, Herms J, Arzberger T & Höglinger G
Long-Duration Progressive Supranuclear Palsy: Clinical Course and Pathological Underpinnings.
Annals of neurology, 2022 Oct, 92 (4) 637-649

Perez-Rivas LG, Simon J, Albani A, Tang S, Roeber S, Assié G, Deutschbein T, Fassnacht M, Gadelha MR, Hermus AR, Stalla GK, Tichomirowa MA, Rotermund R, Flitsch J, Buchfelder M, Nasi-Kordhishti I, Honegger J, Thorsteinsdottir J, Saeger W, Herms J, Reincke M & Theodoropoulou M
TP53 mutations in functional corticotroph tumors are linked to invasion and worse clinical outcome.
Acta neuropathologica communications, 2022 Sep 19, 10 (1) 139

Luger AL, König S, Samp PF, Urban H, Divé I, Burger MC, Voss M, Franz K, Fokas E, Filipski K, Demes MC, Stenzinger A, Sahm F, Reuss DE, Harter PN, Wagner S, Hattingen E, Wichert J, Lapa C, Fröhling S, Steinbach JP & Ronellenfitsch MW
Molecular matched targeted therapies for primary brain tumors-a single center retrospective analysis.
Journal of neuro-oncology, 2022 Sep, 159 (2) 243-259

Schmidt S, Luecken MD, Trümbach D, Hembach S, Niedermeier KM, Wenck N, Pflügler K, Stautner C, Böttcher A, Lickert H, Ramirez-Suastegui C, Ahmad R, Ziller MJ, Fitzgerald JC, Ruf V, van de Berg WDJ, Jonker AJ, Gasser T, Winner B, Winkler J, Vogt Weisenhorn DM, Giesert F, Theis FJ & Wurst W
Primary cilia and SHH signaling impairments in human and mouse models of Parkinson's disease.
Nature communications, 2022 Aug 16, 13 (1) 4819

Albani A, Perez-Rivas LG, Tang S, Simon J, Lucia KE, Colón-Bolea P, Schopohl J, Roeber S, Buchfelder M, Rotermund R, Flitsch J, Thorsteinsdottir J, Herms J, Stalla G, Reincke M & Theodoropoulou M
Improved pasireotide response in USP8 mutant corticotroph tumours in vitro.
Endocrine-related cancer, 2022 Aug 01, 29 (8) 503-511

Spitzer D, Guérit S, Puetz T, Khel MI, Armbrust M, Dunst M, Macas J, Zinke J, Devraj G, Jia X, Croll F, Sommer K, Filipski K, Freiman TM, Looso M, Günther S, Di Tacchio M, Plate KH, Reiss Y, Liebner S, Harter PN & Devraj K
Profiling the neurovascular unit unveils detrimental effects of osteopontin on the blood-brain barrier in acute ischemic stroke.
Acta neuropathologica, 2022 Aug, 144 (2) 305-337

Charidimou A, Boulouis G, Frosch MP, Baron JC, Pasi M, Albucher JF, Banerjee G, Barbato C, Bonneville F, Brandner S, Calviere L, Caparros F, Casolla B, Cordonnier C, Delisle MB, Deramecourt V, Dichgans M, Gokcal E, Herms J, Hernandez-Guillamon M, Jäger HR, Jaunmuktane Z, Linn J, Martinez-Ramirez S, Martínez-Sáez E, Mawrin C, Montaner J, Moulin S, Olivot JM, Piazza F, Puy L, Raposo N, Rodrigues MA, Roeber S, Romero JR, Samarasekera N, Schneider JA, Schreiber S, Schreiber F, Schwall C, Smith C, Szalardy L, Varlet P, Viguier A, Wardlaw JM, Warren A, Wollenweber FA, Zedde M, van Buchem MA, Gurol ME, Viswanathan A, Al-Shahi Salman R, Smith EE, Werring DJ & Greenberg SM
The Boston criteria version 2.0 for cerebral amyloid angiopathy: a multicentre, retrospective, MRI-neuropathology diagnostic accuracy study.
The Lancet. Neurology, 2022 Aug, 21 (8) 714-725

Rupprecht R, Wetzel CH, Dorostkar M, Herms J, Albert NL, Schwarzbach J, Schumacher M & Neumann ID
Translocator protein (18kDa) TSPO: a new diagnostic or therapeutic target for stress-related disorders?
Molecular psychiatry, 2022 Jul, 27 (7) 2918-2926

Unterrainer M, Mahler C, Schumacher AM, Ruf V, Blum B, Quach S, Brendel M, Rupprecht R, Bartenstein P, Kerschensteiner M, Kümpfel T & Albert NL
Amino Acid Uptake, Glucose Metabolism, and Neuroinflammation in John Cunningham Virus Associated Progressive Multifocal Leukoencephalopathy.
Clinical nuclear medicine, 2022 Jun 01, 47 (6) 543-544

Zeiner PS, Filipski K, Filmann N, Forster MT, Voss M, Fokas E, Herrlinger U, Harter PN, Steinbach JP & Ronellenfitsch MW
Sex-Dependent Analysis of Temozolomide-Induced Myelosuppression and Effects on Survival in a Large Real-life Cohort of Patients With Glioma.
Neurology, 2022 May 17, 98 (20) e2073-e2083

Bodensohn R, Forbrig R, Quach S, Reis J, Boulesteix AL, Mansmann U, Hadi I, Fleischmann DF, Mücke J, Holzgreve A, Albert NL, Ruf V, Dorostkar M, Corradini S, Herms J, Belka C, Thon N & Niyazi M
MRI-based contrast clearance analysis shows high differentiation accuracy between radiation-induced reactions and progressive disease after cranial radiotherapy.
ESMO open, 2022 Apr, 7 (2) 100424

Paul T, Ledderose S, Bartsch H, Sun N, Soliman S, Märkl B, Ruf V, Herms J, Stern M, Keppler OT, Delbridge C, Müller S, Piontek G, Kimoto YS, Schreiber F, Williams TA, Neumann J, Knösel T, Schulz H, Spallek R, Graw M, Kirchner T, Walch A & Rudelius M
Adrenal tropism of SARS-CoV-2 and adrenal findings in a post-mortem case series of patients with severe fatal COVID-19.
Nature communications, 2022 Mar 24, 13 (1) 1589

Franzmeier N, Brendel M, Beyer L, Slemann L, Kovacs GG, Arzberger T, Kurz C, Respondek G, Lukic MJ, Biel D, Rubinski A, Frontzkowski L, Hummel S, Müller A, Finze A, Palleis C, Joseph E, Weidinger E, Katzdobler S, Song M, Biechele G, Kern M, Scheifele M, Rauchmann BS, Perneczky R, Rullman M, Patt M, Schildan A, Barthel H, Sabri O, Rumpf JJ, Schroeter ML, Classen J, Villemagne V, Seibyl J, Stephens AW, Lee EB, Coughlin DG, Giese A, Grossman M, McMillan CT, Gelpi E, Molina-Porcel L, Compta Y, van Swieten JC, Laat LD, Troakes C, Al-Sarraj S, Robinson JL, Xie SX, Irwin DJ, Roeber S, Herms J, Simons M, Bartenstein P, Lee VM, Trojanowski JQ, Levin J, Höglinger G & Ewers M
Tau deposition patterns are associated with functional connectivity in primary tauopathies.
Nature communications, 2022 Mar 15, 13 (1) 1362

Sun F, Salinas AG, Filser S, Blumenstock S, Medina-Luque J, Herms J & Sgobio C
Impact of α-synuclein spreading on the nigrostriatal dopaminergic pathway depends on the onset of the pathology.
Brain pathology (Zurich, Switzerland), 2022 Mar, 32 (2) e13036

Shi Y, Cui M, Ochs K, Brendel M, Strübing FL, Briel N, Eckenweber F, Zou C, Banati RB, Liu GJ, Middleton RJ, Rupprecht R, Rudolph U, Zeilhofer HU, Rammes G, Herms J & Dorostkar MM
Long-term diazepam treatment enhances microglial spine engulfment and impairs cognitive performance via the mitochondrial 18 kDa translocator protein (TSPO).
Nature neuroscience, 2022 Mar, 25 (3) 317-329

Zeiner PS, Mann L, Filipski K, Starzetz T, Forster MT, Ronellenfitsch MW, Steinbach JP, Mittelbronn M, Wagner M & Harter PN
Immune profile and radiological characteristics of progressive multifocal leukoencephalopathy.
European journal of neurology, 2022 Feb, 29 (2) 543-554

Tehranian C, Fankhauser L, Harter PN, Ratcliffe CDH, Zeiner PS, Messmer JM, Hoffmann DC, Frey K, Westphal D, Ronellenfitsch MW, Sahai E, Wick W, Karreman MA & Winkler F
The PI3K/Akt/mTOR pathway as a preventive target in melanoma brain metastasis.
Neuro-oncology, 2022 Feb 01, 24 (2) 213-225

Liao C, Castonguay CE, Heilbron K, Vuokila V, Medeiros M, Houle G, Akçimen F, Ross JP, Catoire H, Diez-Fairen M, Kang J, Mueller SH, Girard SL, Hopfner F, Lorenz D, Clark LN, Soto-Beasley AI, Klebe S, Hallett M, Wszolek ZK, Pendziwiat M, Lorenzo-Betancor O, Seppi K, Berg D, Vilariño-Güell C, Postuma RB, Bernard G, Dupré N, Jankovic J, Testa CM, Ross OA, Arzberger T, Chouinard S, Louis ED, Mandich P, Vitale C, Barone P, García-Martín E, Alonso-Navarro H, Agúndez JAG, Jiménez-Jiménez FJ, Pastor P, Rajput A, Deuschl G, Kuhlenbaümer G, Meijer IA, Dion PA, Rouleau GA & 23andMe Research Team
Association of Essential Tremor With Novel Risk Loci: A Genome-Wide Association Study and Meta-analysis.
JAMA neurology, 2022 Feb 01, 79 (2) 185-193

Voss M, Wenger KJ, von Mettenheim N, Bojunga J, Vetter M, Diehl B, Franz K, Gerlach R, Ronellenfitsch MW, Harter PN, Hattingen E, Steinbach JP, Rödel C & Rieger J
Short-term fasting in glioma patients: analysis of diet diaries and metabolic parameters of the ERGO2 trial.
European journal of nutrition, 2022 Feb, 61 (1) 477-487

Zellner A, Müller SA, Lindner B, Beaufort N, Rozemuller AJM, Arzberger T, Gassen NC, Lichtenthaler SF, Kuster B, Haffner C & Dichgans M
Proteomic profiling in cerebral amyloid angiopathy reveals an overlap with CADASIL highlighting accumulation of HTRA1 and its substrates.
Acta neuropathologica communications, 2022 Jan 24, 10 (1) 6

Ebrahimi A, Korshunov A, Reifenberger G, Capper D, Felsberg J, Trisolini E, Pollo B, Calatozzolo C, Prinz M, Staszewski O, Schweizer L, Schittenhelm J, Harter PN, Paulus W, Thomas C, Kohlhof-Meinecke P, Seiz-Rosenhagen M, Milde T, Casalini BM, Suwala A, Wefers AK, Reinhardt A, Sievers P, Kramm CM, Etminam N, Unterberg A, Wick W, Herold-Mende C, Sturm D, Pfister SM, Sill M, Jones DTW, Schrimpf D, Reuss DE, Aldape K, Abdullaev Z, Sahm F, von Deimling A & Stichel D
Pleomorphic xanthoastrocytoma is a heterogeneous entity with pTERT mutations prognosticating shorter survival.
Acta neuropathologica communications, 2022 Jan 10, 10 (1) 5

Vöglein J, Kostova I, Arzberger T, Noachtar S, Dieterich M, Herms J, Schmitz P, Ruf V, Windl O, Roeber S, Simons M, Höglinger GU, Danek A, Giese A & Levin J
Seizure prevalence in neurodegenerative diseases-a study of autopsy proven cases.
European journal of neurology, 2022 Jan, 29 (1) 12-18

Teske N, Karschnia P, Weller J, Siller S, Dorostkar MM, Herms J, von Baumgarten L, Tonn JC & Thon N
Extent, pattern, and prognostic value of MGMT promotor methylation: does it differ between glioblastoma and IDH-wildtype/TERT-mutated astrocytoma?
Journal of neuro-oncology, 2022 Jan, 156 (2) 317-327

Biechele G, Monasor LS, Wind K, Blume T, Parhizkar S, Arzberger T, Sacher C, Beyer L, Eckenweber F, Gildehaus FJ, von Ungern-Sternberg B, Willem M, Bartenstein P, Cumming P, Rominger A, Herms J, Lichtenthaler SF, Haass C, Tahirovic S & Brendel M
Glitter in the Darkness? Nonfibrillar β-Amyloid Plaque Components Significantly Impact the β-Amyloid PET Signal in Mouse Models of Alzheimer Disease.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2022 Jan, 63 (1) 117-124

Katzendobler S, Do A, Weller J, Rejeski K, Dorostkar MM, Albert NL, Forbrig R, Niyazi M, Egensperger R, Tonn JC, von Baumgarten L, Quach S & Thon N
The value of stereotactic biopsy of primary and recurrent brain metastases in the era of precision medicine.
Frontiers in oncology, 2022, 12 1014711

Blume T, Filser S, Sgobio C, Peters F, Neumann U, Shimshek D, Saito T, Saido TC, Brendel M & Herms J
β-secretase inhibition prevents structural spine plasticity deficits in App NL-G-F mice.
Frontiers in aging neuroscience, 2022, 14 909586

Fanciulli A, Leys F, Lehner F, Sidoroff V, Ruf VC, Raccagni C, Mahlknecht P, Kuipers DJS, van IJcken WFJ, Stockner H, Musacchio T, Volkmann J, Monoranu CM, Stankovic I, Breedveld G, Ferraro F, Fevga C, Windl O, Herms J, Kiechl S, Poewe W, Seppi K, Stefanova N, Scholz SW, Bonifati V & Wenning GK
A multiplex pedigree with pathologically confirmed multiple system atrophy and Parkinson's disease with dementia.
Brain communications, 2022, 4 (4) fcac175

Blume T, Deussing M, Biechele G, Peters F, Zott B, Schmidt C, Franzmeier N, Wind K, Eckenweber F, Sacher C, Shi Y, Ochs K, Kleinberger G, Xiang X, Focke C, Lindner S, Gildehaus FJ, Beyer L, von Ungern-Sternberg B, Bartenstein P, Baumann K, Adelsberger H, Rominger A, Cumming P, Willem M, Dorostkar MM, Herms J & Brendel M
Chronic PPARγ Stimulation Shifts Amyloidosis to Higher Fibrillarity but Improves Cognition.
Frontiers in aging neuroscience, 2022, 14 854031

Katzendobler S, Do A, Weller J, Dorostkar MM, Albert NL, Forbrig R, Niyazi M, Egensperger R, Thon N, Tonn JC & Quach S
Diagnostic Yield and Complication Rate of Stereotactic Biopsies in Precision Medicine of Gliomas.
Frontiers in neurology, 2022, 13 822362

Dorostkar MM, Konnerth D, Niyazi M, Thon N, Schlaak M, Hayani K & Guertler A
Anaplastic pleomorphic xanthoastrocytoma with epithelioid morphology misdiagnosed and treated as melanoma.
Neuro-oncology advances, 2022, 4 (1) vdac009

2021

Kolorz J, Demir S, Gottschlich A, Beirith I, Ilmer M, Lüthy D, Walz C, Dorostkar MM, Magg T, Hauck F, von Schweinitz D, Kobold S, Kappler R & Berger M
The Neurokinin-1 Receptor Is a Target in Pediatric Rhabdoid Tumors.
Current oncology (Toronto, Ont.), 2021 Dec 26, 29 (1) 94-110

Kaiser L, Holzgreve A, Quach S, Ingrisch M, Unterrainer M, Dekorsy FJ, Lindner S, Ruf V, Brosch-Lenz J, Delker A, Böning G, Suchorska B, Niyazi M, Wetzel CH, Riemenschneider MJ, Stöcklein S, Brendel M, Rupprecht R, Thon N, von Baumgarten L, Tonn JC, Bartenstein P, Ziegler S & Albert NL
Differential Spatial Distribution of TSPO or Amino Acid PET Signal and MRI Contrast Enhancement in Gliomas.
Cancers, 2021 Dec 23, 14 (1)

Vettermann FJ, Diekmann C, Weidner L, Unterrainer M, Suchorska B, Ruf V, Dorostkar M, Wenter V, Herms J, Tonn JC, Bartenstein P, Riemenschneider MJ & Albert NL
L-type amino acid transporter (LAT) 1 expression in 18F-FET-negative gliomas.
EJNMMI research, 2021 Dec 14, 11 (1) 124

Schmid S, Solomon DA, Perez E, Thieme A, Kleinschmidt-DeMasters BK, Giannini C, Reinhardt A, Asa SL, Mete O, Stichel D, Siewert C, Dittmayer C, Hasselblatt M, Paulus W, Nagel C, Harter PN, Schittenhelm J, Honegger J, Rushing E, Coras R, Pfister SM, Buslei R, Koch A, Perry A, Jones DTW, von Deimling A, Capper D & Lopes MB
Genetic and epigenetic characterization of posterior pituitary tumors.
Acta neuropathologica, 2021 Dec, 142 (6) 1025-1043

Hagel C, Schüller U, Flitsch J, Knappe UJ, Kellner U, Bergmann M, Buslei R, Buchfelder M, Rüdiger T, Herms J & Saeger W
Double adenomas of the pituitary reveal distinct lineage markers, copy number alterations, and epigenetic profiles.
Pituitary, 2021 Dec, 24 (6) 904-913

Maas SLN, Stichel D, Hielscher T, Sievers P, Berghoff AS, Schrimpf D, Sill M, Euskirchen P, Blume C, Patel A, Dogan H, Reuss D, Dohmen H, Stein M, Reinhardt A, Suwala AK, Wefers AK, Baumgarten P, Ricklefs F, Rushing EJ, Bewerunge-Hudler M, Ketter R, Schittenhelm J, Jaunmuktane Z, Leu S, Greenway FEA, Bridges LR, Jones T, Grady C, Serrano J, Golfinos J, Sen C, Mawrin C, Jungk C, Hänggi D, Westphal M, Lamszus K, Etminan N, Jungwirth G, Herold-Mende C, Unterberg A, Harter PN, Wirsching HG, Neidert MC, Ratliff M, Platten M, Snuderl M, Aldape KD, Brandner S, Hench J, Frank S, Pfister SM, Jones DTW, Reifenberger G, Acker T, Wick W, Weller M, Preusser M, von Deimling A, Sahm F & German Consortium on Aggressive Meningiomas (KAM)
Integrated Molecular-Morphologic Meningioma Classification: A Multicenter Retrospective Analysis, Retrospectively and Prospectively Validated.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2021 Dec 01, 39 (34) 3839-3852

Korzhova V, Marinković P, Njavro JR, Goltstein PM, Sun F, Tahirovic S, Herms J & Liebscher S
Long-term dynamics of aberrant neuronal activity in awake Alzheimer's disease transgenic mice.
Communications biology, 2021 Dec 07, 4 (1) 1368

Levin J, Nübling G, Giese A, Janzen A & Oertel W
[Neuroprotective treatment of idiopathic, genetic and atypical Parkinson's disease with alpha-synuclein-Pathology].
Der Nervenarzt, 2021 Dec, 92 (12) 1249-1259

Li Z, Kaiser L, Holzgreve A, Ruf VC, Suchorska B, Wenter V, Quach S, Herms J, Bartenstein P, Tonn JC, Unterrainer M & Albert NL
Prediction of TERTp-mutation status in IDH-wildtype high-grade gliomas using pre-treatment dynamic [18F]FET PET radiomics.
European journal of nuclear medicine and molecular imaging, 2021 Dec, 48 (13) 4415-4425

Tirado-Gonzalez I, Descot A, Soetopo D, Nevmerzhitskaya A, Schäffer A, Kur IM, Czlonka E, Wachtel C, Tsoukala I, Müller L, Schäfer AL, Weitmann M, Dinse P, Alberto E, Buck MC, Landry JJ, Baying B, Slotta-Huspenina J, Roesler J, Harter PN, Kubasch AS, Meinel J, Elwakeel E, Strack E, Quang CT, Abdel-Wahab O, Schmitz M, Weigert A, Schmid T, Platzbecker U, Benes V, Ghysdael J, Bonig H, Götze KS, Rothlin CV, Ghosh S & Medyouf H
AXL Inhibition in Macrophages Stimulates Host-versus-Leukemia Immunity and Eradicates Naïve and Treatment-Resistant Leukemia.
Cancer discovery, 2021 Nov, 11 (11) 2924-2943

Song M, Beyer L, Kaiser L, Barthel H, van Eimeren T, Marek K, Nitschmann A, Scheifele M, Palleis C, Respondek G, Kern M, Biechele G, Hammes J, Bischof G, Barbe M, Onur Ö, Jessen F, Saur D, Schroeter ML, Rumpf JJ, Rullmann M, Schildan A, Patt M, Neumaier B, Barret O, Madonia J, Russell DS, Stephens AW, Mueller A, Roeber S, Herms J, Bötzel K, Danek A, Levin J, Classen J, Höglinger GU, Bartenstein P, Villemagne V, Drzezga A, Seibyl J, Sabri O, Boening G, Ziegler S & Brendel M
Binding characteristics of [18F]PI-2620 distinguish the clinically predicted tau isoform in different tauopathies by PET.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2021 Nov, 41 (11) 2957-2972

Sievers P, Henneken SC, Blume C, Sill M, Schrimpf D, Stichel D, Okonechnikov K, Reuss DE, Benzel J, Maaß KK, Kool M, Sturm D, Zheng T, Ghasemi DR, Kohlhof-Meinecke P, Cruz O, Suñol M, Lavarino C, Ruf V, Boldt HB, Pagès M, Pouget C, Schweizer L, Kranendonk MEG, Akhtar N, Bunkowski S, Stadelmann C, Schüller U, Mueller WC, Dohmen H, Acker T, Harter PN, Mawrin C, Beschorner R, Brandner S, Snuderl M, Abdullaev Z, Aldape K, Gilbert MR, Armstrong TS, Ellison DW, Capper D, Ichimura K, Reifenberger G, Grundy RG, Jabado N, Krskova L, Zapotocky M, Vicha A, Varlet P, Wesseling P, Rutkowski S, Korshunov A, Wick W, Pfister SM, Jones DTW, von Deimling A, Pajtler KW & Sahm F
Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors.
Acta neuropathologica, 2021 Nov, 142 (5) 827-839

Joshi P, Riffel F, Kumar S, Villacampa N, Theil S, Parhizkar S, Haass C, Colonna M, Heneka MT, Arzberger T, Herms J & Walter J
TREM2 modulates differential deposition of modified and non-modified Aβ species in extracellular plaques and intraneuronal deposits.
Acta neuropathologica communications, 2021 Oct 18, 9 (1) 168

Xiang X, Wind K, Wiedemann T, Blume T, Shi Y, Briel N, Beyer L, Biechele G, Eckenweber F, Zatcepin A, Lammich S, Ribicic S, Tahirovic S, Willem M, Deussing M, Palleis C, Rauchmann BS, Gildehaus FJ, Lindner S, Spitz C, Franzmeier N, Baumann K, Rominger A, Bartenstein P, Ziegler S, Drzezga A, Respondek G, Buerger K, Perneczky R, Levin J, Höglinger GU, Herms J, Haass C & Brendel M
Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases.
Science translational medicine, 2021 Oct 13, 13 (615) eabe5640

Klemm F, Möckl A, Salamero-Boix A, Alekseeva T, Schäffer A, Schulz M, Niesel K, Maas RR, Groth M, Elie BT, Bowman RL, Hegi ME, Daniel RT, Zeiner PS, Zinke J, Harter PN, Plate KH, Joyce JA & Sevenich L
Compensatory CSF2-driven macrophage activation promotes adaptive resistance to CSF1R inhibition in breast-to-brain metastasis.
Nature cancer, 2021 Oct, 2 (10) 1086-1101

Baiardi S, Rossi M, Mammana A, Appleby BS, Barria MA, Calì I, Gambetti P, Gelpi E, Giese A, Ghetti B, Herms J, Ladogana A, Mikol J, Pal S, Ritchie DL, Ruf V, Windl O, Capellari S & Parchi P
Phenotypic diversity of genetic Creutzfeldt-Jakob disease: a histo-molecular-based classification.
Acta neuropathologica, 2021 Oct, 142 (4) 707-728

Wirsik NM, Ehlers J, Mäder L, Ilina EI, Blank AE, Grote A, Feuerhake F, Baumgarten P, Devraj K, Harter PN, Mittelbronn M & Naumann U
TGF-β activates pericytes via induction of the epithelial-to-mesenchymal transition protein SLUG in glioblastoma.
Neuropathology and applied neurobiology, 2021 Oct, 47 (6) 768-780

Karschnia P, Weller J, Blobner J, Stoecklein VM, Dorostkar MM, Rejeski K, Forbrig R, Niyazi M, von Baumgarten L, Dietrich J, Tonn JC & Thon N
Subventricular zone involvement is associated with worse outcome in glioma WHO grade 2 depending on molecular markers.
Scientific reports, 2021 Oct 08, 11 (1) 20045

Biczok A, Karschnia P, Vitalini R, Lenski M, Greve T, Thorsteinsdottir J, Egensperger R, Dorn F, Tonn JC & Schichor C
Past medical history of tumors other than meningioma is a negative prognostic factor for tumor recurrence in meningiomas WHO grade I.
Acta neurochirurgica, 2021 Oct, 163 (10) 2853-2859

Romano M, Bravin A, Mittone A, Eckhardt A, Barbone GE, Sancey L, Dinkel J, Bartzsch S, Ricke J, Alunni-Fabbroni M, Hirner-Eppeneder H, Karpov D, Giannini C, Bunk O, Bouchet A, Ruf V, Giese A & Coan P
A Multi-Scale and Multi-Technique Approach for the Characterization of the Effects of Spatially Fractionated X-ray Radiation Therapies in a Preclinical Model.
Cancers, 2021 Oct 01, 13 (19)

Tang Q, Gao P, Arzberger T, Höllerhage M, Herms J, Höglinger G & Koeglsperger T
Alpha-Synuclein defects autophagy by impairing SNAP29-mediated autophagosome-lysosome fusion.
Cell death & disease, 2021 Sep 17, 12 (10) 854

Fleischmann DF, Schön R, Corradini S, Bodensohn R, Hadi I, Hofmaier J, Forbrig R, Thon N, Dorostkar M, Belka C & Niyazi M
Multifocal high-grade glioma radiotherapy safety and efficacy.
Radiation oncology (London, England), 2021 Aug 28, 16 (1) 165

Verkuijl SJ, Friedmacher F, Harter PN, Rolle U & Broens PM
Persistent bowel dysfunction after surgery for Hirschsprung's disease: A neuropathological perspective.
World journal of gastrointestinal surgery, 2021 Aug 27, 13 (8) 822-833

Maurer GD, Tichy J, Harter PN, Nöth U, Weise L, Quick-Weller J, Deichmann R, Steinbach JP, Bähr O & Hattingen E
Matching Quantitative MRI Parameters with Histological Features of Treatment-Naïve IDH Wild-Type Glioma.
Cancers, 2021 Aug 12, 13 (16)

Heindl S, Ricci A, Carofiglio O, Zhou Q, Arzberger T, Lenart N, Franzmeier N, Hortobagyi T, Nelson PT, Stowe AM, Denes A, Edbauer D & Liesz A
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
The Journal of experimental medicine, 2021 Aug 02, 218 (8)

Steidl E, Filipski K, Zeiner PS, Wagner M, Fokas E, Forster MT, Ronellenfitsch MW, Divé I, Steinbach JP, Harter PN & Bähr O
A 25-year retrospective, single center analysis of 343 WHO grade II/III glioma patients: implications for grading and temozolomide therapy.
Journal of cancer research and clinical oncology, 2021 Aug, 147 (8) 2373-2383

Neef V, König S, Monden D, Dubinski D, Benesch A, Raimann FJ, Piekarski F, Ronellenfitsch MW, Harter PN, Senft C, Meybohm P, Hattingen E, Zacharowski K, Seifert V & Baumgarten P
Clinical Outcome and Risk Factors of Red Blood Cell Transfusion in Patients Undergoing Elective Primary Meningioma Resection.
Cancers, 2021 Jul 18, 13 (14)

Filipski K, Scherer M, Zeiner KN, Bucher A, Kleemann J, Jurmeister P, Hartung TI, Meissner M, Plate KH, Fenton TR, Walter J, Tierling S, Schilling B, Zeiner PS & Harter PN
DNA methylation-based prediction of response to immune checkpoint inhibition in metastatic melanoma.
Journal for immunotherapy of cancer, 2021 Jul, 9 (7)

Suwala AK, Stichel D, Schrimpf D, Maas SLN, Sill M, Dohmen H, Banan R, Reinhardt A, Sievers P, Hinz F, Blattner-Johnson M, Hartmann C, Schweizer L, Boldt HB, Kristensen BW, Schittenhelm J, Wood MD, Chotard G, Bjergvig R, Das A, Tabori U, Hasselblatt M, Korshunov A, Abdullaev Z, Quezado M, Aldape K, Harter PN, Snuderl M, Hench J, Frank S, Acker T, Brandner S, Winkler F, Wesseling P, Pfister SM, Reuss DE, Wick W, von Deimling A, Jones DTW & Sahm F
Glioblastomas with primitive neuronal component harbor a distinct methylation and copy-number profile with inactivation of TP53, PTEN, and RB1.
Acta neuropathologica, 2021 Jul, 142 (1) 179-189

Biczok A, Strübing FL, Eder JM, Egensperger R, Schnell O, Zausinger S, Neumann JE, Herms J, Tonn JC & Dorostkar MM
Molecular diagnostics helps to identify distinct subgroups of spinal astrocytomas.
Acta neuropathologica communications, 2021 Jun 30, 9 (1) 119

Loreth D, Schuette M, Zinke J, Mohme M, Piffko A, Schneegans S, Stadler J, Janning M, Loges S, Joosse SA, Lamszus K, Westphal M, Müller V, Glatzel M, Matschke J, Gebhardt C, Schneider SW, Belczacka I, Volkmer B, Greinert R, Yaspo ML, Harter PN, Pantel K & Wikman H
CD74 and CD44 Expression on CTCs in Cancer Patients with Brain Metastasis.
International journal of molecular sciences, 2021 Jun 29, 22 (13)

Mittlmeier LM, Suchorska B, Ruf V, Holzgreve A, Brendel M, Herms J, Bartenstein P, Tonn JC, Unterrainer M & Albert NL
18F-FET PET Uptake Characteristics of Long-Term IDH-Wildtype Diffuse Glioma Survivors.
Cancers, 2021 Jun 24, 13 (13)

Smith RG, Pishva E, Shireby G, Smith AR, Roubroeks JAY, Hannon E, Wheildon G, Mastroeni D, Gasparoni G, Riemenschneider M, Giese A, Sharp AJ, Schalkwyk L, Haroutunian V, Viechtbauer W, van den Hove DLA, Weedon M, Brokaw D, Francis PT, Thomas AJ, Love S, Morgan K, Walter J, Coleman PD, Bennett DA, De Jager PL, Mill J & Lunnon K
A meta-analysis of epigenome-wide association studies in Alzheimer's disease highlights novel differentially methylated loci across cortex.
Nature communications, 2021 Jun 10, 12 (1) 3517

Kresbach C, Dorostkar MM, Suwala AK, Wefers AK, Schweizer L, Engertsberger L, Bison B, Mynarek M, Kloth-Stachnau K, Spohn M, von Deimling A, Benesch M, Hagel C, Mautner VF, Rutkowski S & Schüller U
Neurofibromatosis type 2 predisposes to ependymomas of various localization, histology, and molecular subtype.
Acta neuropathologica, 2021 Jun, 141 (6) 971-974

Thomas C, Thierfelder F, Träger M, Soschinski P, Müther M, Edelmann D, Förster A, Geiler C, Kim HY, Filipski K, Harter PN, Schittenhelm J, Eckert F, Ntoulias G, May SA, Stummer W, Onken J, Vajkoczy P, Schüller U, Heppner FL, Capper D, Koch A, Kaul D, Paulus W, Hasselblatt M & Schweizer L
TERT promoter mutation and chromosome 6 loss define a high-risk subtype of ependymoma evolving from posterior fossa subependymoma.
Acta neuropathologica, 2021 Jun, 141 (6) 959-970

Weller J, Katzendobler S, Karschnia P, Lietke S, Egensperger R, Thon N, Weller M, Suchorska B & Tonn JC
PCV chemotherapy alone for WHO grade 2 oligodendroglioma: prolonged disease control with low risk of malignant progression.
Journal of neuro-oncology, 2021 Jun, 153 (2) 283-291

Vöglein J, Kostova I, Arzberger T, Roeber S, Schmitz P, Simons M, Ruf V, Windl O, Herms J, Dieterich M, Danek A, Höglinger GU, Giese A & Levin J
First symptom guides diagnosis and prognosis in neurodegenerative diseases-a retrospective study of autopsy proven cases.
European journal of neurology, 2021 Jun, 28 (6) 1801-1811

Kuebler L, Buss S, Leonov A, Ryazanov S, Schmidt F, Maurer A, Weckbecker D, Landau AM, Lillethorup TP, Bleher D, Saw RS, Pichler BJ, Griesinger C, Giese A & Herfert K
[11C]MODAG-001-towards a PET tracer targeting α-synuclein aggregates.
European journal of nuclear medicine and molecular imaging, 2021 Jun, 48 (6) 1759-1772

Monden D, Raimann FJ, Neef V, Dubinski D, Gessler F, Keil F, Forster MT, Ronellenfitsch MW, Harter PN, Freiman TM, Hattingen E, Seifert V, Senft C & Baumgarten P
Meningioma Surgery in Patients ≥70 Years of Age: Clinical Outcome and Validation of the SKALE Score.
Journal of clinical medicine, 2021 Apr 22, 10 (9)

Biechele G, Wind K, Blume T, Sacher C, Beyer L, Eckenweber F, Franzmeier N, Ewers M, Zott B, Lindner S, Gildehaus FJ, von Ungern-Sternberg B, Tahirovic S, Willem M, Bartenstein P, Cumming P, Rominger A, Herms J & Brendel M
Microglial activation in the right amygdala-entorhinal-hippocampal complex is associated with preserved spatial learning in AppNL-G-F mice.
NeuroImage, 2021 Apr 15, 230 117707

Trinkaus VA, Riera-Tur I, Martínez-Sánchez A, Bäuerlein FJB, Guo Q, Arzberger T, Baumeister W, Dudanova I, Hipp MS, Hartl FU & Fernández-Busnadiego R
In situ architecture of neuronal α-Synuclein inclusions.
Nature communications, 2021 Apr 14, 12 (1) 2110

Colombo AV, Sadler RK, Llovera G, Singh V, Roth S, Heindl S, Sebastian Monasor L, Verhoeven A, Peters F, Parhizkar S, Kamp F, Gomez de Aguero M, MacPherson AJ, Winkler E, Herms J, Benakis C, Dichgans M, Steiner H, Giera M, Haass C, Tahirovic S & Liesz A
Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition.
eLife, 2021 Apr 13, 10

Bernatz S, Monden D, Gessler F, Radic T, Hattingen E, Senft C, Seifert V, Ronellenfitsch MW, Plate KH, Harter PN & Baumgarten P
Influence of VEGF-A, VEGFR-1-3, and neuropilin 1-2 on progression-free: and overall survival in WHO grade II and III meningioma patients.
Journal of molecular histology, 2021 Apr, 52 (2) 233-243

Braun Y, Filipski K, Bernatz S, Baumgarten P, Roller B, Zinke J, Zeiner PS, Ilina E, Senft C, Ronellenfitsch MW, Plate KH, Bähr O, Hattingen E, Steinbach JP, Mittelbronn M & Harter PN
Linking epigenetic signature and metabolic phenotype in IDH mutant and IDH wildtype diffuse glioma.
Neuropathology and applied neurobiology, 2021 Apr, 47 (3) 379-393

Palleis C, Sauerbeck J, Beyer L, Harris S, Schmitt J, Morenas-Rodriguez E, Finze A, Nitschmann A, Ruch-Rubinstein F, Eckenweber F, Biechele G, Blume T, Shi Y, Weidinger E, Prix C, Bötzel K, Danek A, Rauchmann BS, Stöcklein S, Lindner S, Unterrainer M, Albert NL, Wetzel C, Rupprecht R, Rominger A, Bartenstein P, Herms J, Perneczky R, Haass C, Levin J, Höglinger GU & Brendel M
In Vivo Assessment of Neuroinflammation in 4-Repeat Tauopathies.
Movement disorders : official journal of the Movement Disorder Society, 2021 Apr, 36 (4) 883-894

Lietke S, Schmutzer M, Schwartz C, Weller J, Siller S, Aumiller M, Heckl C, Forbrig R, Niyazi M, Egensperger R, Stepp H, Sroka R, Tonn JC, Rühm A & Thon N
Interstitial Photodynamic Therapy Using 5-ALA for Malignant Glioma Recurrences.
Cancers, 2021 Apr 07, 13 (8)

Siller S, Lauseker M, Karschnia P, Niyazi M, Eigenbrod S, Giese A & Tonn JC
The number of methylated CpG sites within the MGMT promoter region linearly correlates with outcome in glioblastoma receiving alkylating agents.
Acta neuropathologica communications, 2021 Mar 04, 9 (1) 35

Reis J, Stahl R, Zimmermann H, Ruf V, Thon N, Kunz M, Liebig T & Forbrig R
Advanced MRI Findings in Medulloblastomas: Relationship to Genetic Subtypes, Histopathology, and Immunohistochemistry.
Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2021 Mar, 31 (2) 306-316

Mann C, Conradi N, Freiman TM, Spyrantis A, Konczalla J, Hattingen E, Wagner M, Harter PN, Mueller M, Leyer AC, Reif PS, Bauer S, Schubert-Bast S, Strzelczyk A & Rosenow F
Postoperative outcomes and surgical ratio at a newly established epilepsy center: The first 100 procedures.
Epilepsy & behavior : E&B, 2021 Mar, 116 107715

Karschnia P, Strübing F, Teske N, Blumenberg V, Bücklein VL, Schmidt C, Schöberl F, Dimitriadis K, Forbrig R, Stemmler HJ, Tonn JC, von Bergwelt-Baildon M, Subklewe M & von Baumgarten L
Clinicopathologic Findings in Fatal Neurotoxicity After Adoptive Immunotherapy With CD19-Directed CAR T-Cells.
HemaSphere, 2021 Mar, 5 (3) e533

Schüller U, Iglauer P, Dorostkar MM, Mawrin C, Herms J, Giese A, Glatzel M & Neumann JE
Mutations within FGFR1 are associated with superior outcome in a series of 83 diffuse midline gliomas with H3F3A K27M mutations.
Acta neuropathologica, 2021 Feb, 141 (2) 323-325

Sievers P, Sill M, Schrimpf D, Stichel D, Reuss DE, Sturm D, Hench J, Frank S, Krskova L, Vicha A, Zapotocky M, Bison B, Castel D, Grill J, Debily MA, Harter PN, Snuderl M, Kramm CM, Reifenberger G, Korshunov A, Jabado N, Wesseling P, Wick W, Solomon DA, Perry A, Jacques TS, Jones C, Witt O, Pfister SM, von Deimling A, Jones DTW & Sahm F
A subset of pediatric-type thalamic gliomas share a distinct DNA methylation profile, H3K27me3 loss and frequent alteration of EGFR.
Neuro-oncology, 2021 Jan 30, 23 (1) 34-43

Baumgarten P, Sarlak M, Monden D, Spyrantis A, Bernatz S, Gessler F, Dubinski D, Hattingen E, Marquardt G, Strzelczyk A, Rosenow F, Harter PN, Seifert V & Freiman TM
Early and Late Postoperative Seizures in Meningioma Patients and Prediction by a Recent Scoring System.
Cancers, 2021 Jan 25, 13 (3)

Biechele G, Blume T, Deussing M, Zott B, Shi Y, Xiang X, Franzmeier N, Kleinberger G, Peters F, Ochs K, Focke C, Sacher C, Wind K, Schmidt C, Lindner S, Gildehaus FJ, Eckenweber F, Beyer L, von Ungern-Sternberg B, Bartenstein P, Baumann K, Dorostkar MM, Rominger A, Cumming P, Willem M, Adelsberger H, Herms J & Brendel M
Pre-therapeutic microglia activation and sex determine therapy effects of chronic immunomodulation.
Theranostics, 2021, 11 (18) 8964-8976

Puladi B, Dinekov M, Arzberger T, Taubert M & Köhler C
The relation between tau pathology and granulovacuolar degeneration of neurons.
Neurobiology of disease, 2021 Jan, 147 105138

Lauer M, Lauer A, You SJ, Kluge S, Hattingen E, Harter PN, Senft C, Wagner M & Voss M
Neurotoxicity of subarachnoid Gd-based contrast agent accumulation: a potential complication of intraoperative MRI?
Neurosurgical focus, 2021 Jan, 50 (1) E12

Dubinski D, Won SY, Rauch M, Behmanesh B, Ngassam LDC, Baumgarten P, Senft C, Harter PN, Bernstock JD, Freiman TM, Seifert V & Gessler F
Association of Isocitrate Dehydrogenase (IDH) Status With Edema to Tumor Ratio and Its Correlation With Immune Infiltration in Glioblastoma.
Frontiers in immunology, 2021, 12 627650

Yamamoto Y, Hase Y, Ihara M, Khundakar A, Roeber S, Duering M & Kalaria RN
Neuronal densities and vascular pathology in the hippocampal formation in CADASIL.
Neurobiology of aging, 2021 Jan, 97 33-40

Stoecklein VM, Kellert L, Patzig M, Küpper C, Giese A, Ruf V, Weller J, Kreth FW & Schöberl F
Extended stereotactic brain biopsy in suspected primary central nervous system angiitis: good diagnostic accuracy and high safety.
Journal of neurology, 2021 Jan, 268 (1) 367-376

Divé I, Steidl E, Wagner M, Filipski K, Burger MC, Franz K, Harter PN, Bähr O, Fokas E, Herrlinger U & Steinbach JP
Gliomatosis Cerebri Growth Pattern: Association of Differential First-Line Treatment with Overall Survival in WHO Grade II and III Gliomas.
Oncology, 2021, 99 (4) 215-224

Duchatel RJ, Mannan A, Woldu AS, Hawtrey T, Hindley PA, Douglas AM, Jackson ER, Findlay IJ, Germon ZP, Staudt D, Kearney PS, Smith ND, Hindley KE, Cain JE, André N, La Madrid AM, Nixon B, De Iuliis GN, Nazarian J, Irish K, Alvaro F, Eisenstat DD, Beck A, Vitanza NA, Mueller S, Morris JC & Dun MD
Preclinical and clinical evaluation of German-sourced ONC201 for the treatment of H3K27M-mutant diffuse intrinsic pontine glioma.
Neuro-oncology advances, 2021, 3 (1) vdab169

Kirchner MA, Holzgreve A, Brendel M, Orth M, Ruf VC, Steiger K, Pötter D, Gold L, Unterrainer M, Mittlmeier LM, Barci E, Kälin RE, Glass R, Lindner S, Kaiser L, Maas J, von Baumgarten L, Ilhan H, Belka C, Notni J, Bartenstein P, Lauber K & Albert NL
PSMA PET Imaging in Glioblastoma: A Preclinical Evaluation and Theranostic Outlook.
Frontiers in oncology, 2021, 11 774017

Blumenstock S, Sun F, Klaus C, Marinković P, Sgobio C, Paeger L, Liebscher S & Herms J
Cortical circuit dysfunction in a mouse model of alpha-synucleinopathy in vivo.
Brain communications, 2021, 3 (4) fcab273

Willroider M, Roeber S, Horn AKE, Arzberger T, Scheifele M, Respondek G, Sabri O, Barthel H, Patt M, Mishchenko O, Schildan A, Mueller A, Koglin N, Stephens A, Levin J, Höglinger GU, Bartenstein P, Herms J, Brendel M & Beyer L
Superiority of Formalin-Fixed Paraffin-Embedded Brain Tissue for in vitro Assessment of Progressive Supranuclear Palsy Tau Pathology With [ 18 F]PI-2620.
Frontiers in neurology, 2021, 12 684523

Unterrainer M, Ruf V, von Rohr K, Suchorska B, Mittlmeier LM, Beyer L, Brendel M, Wenter V, Kunz WG, Bartenstein P, Herms J, Niyazi M, Tonn JC & Albert NL
TERT-Promoter Mutational Status in Glioblastoma - Is There an Association With Amino Acid Uptake on Dynamic 18F-FET PET?
Frontiers in oncology, 2021, 11 645316

Holzgreve A, Biczok A, Ruf VC, Liesche-Starnecker F, Steiger K, Kirchner MA, Unterrainer M, Mittlmeier L, Herms J, Schlegel J, Bartenstein P, Tonn JC, Albert NL & Suchorska B
PSMA Expression in Glioblastoma as a Basis for Theranostic Approaches: A Retrospective, Correlational Panel Study Including Immunohistochemistry, Clinical Parameters and PET Imaging.
Frontiers in oncology, 2021, 11 646387

2020

Grimm MJ, Respondek G, Stamelou M, Arzberger T, Ferguson L, Gelpi E, Giese A, Grossman M, Irwin DJ, Pantelyat A, Rajput A, Roeber S, van Swieten JC, Troakes C, Meissner WG, Nilsson C, Piot I, Compta Y, Rowe JB, Höglinger GU & Movement Disorder Society-Endorsed PSP Study Group
Clinical Conditions "Suggestive of Progressive Supranuclear Palsy"-Diagnostic Performance.
Movement disorders : official journal of the Movement Disorder Society, 2020 Dec, 35 (12) 2301-2313

Bernatz S, Ackermann J, Mandel P, Kaltenbach B, Zhdanovich Y, Harter PN, Döring C, Hammerstingl R, Bodelle B, Smith K, Bucher A, Albrecht M, Rosbach N, Basten L, Yel I, Wenzel M, Bankov K, Koch I, Chun FK, Köllermann J, Wild PJ & Vogl TJ
Comparison of machine learning algorithms to predict clinically significant prostate cancer of the peripheral zone with multiparametric MRI using clinical assessment categories and radiomic features.
European radiology, 2020 Dec, 30 (12) 6757-6769

Sacher C, Blume T, Beyer L, Biechele G, Sauerbeck J, Eckenweber F, Deussing M, Focke C, Parhizkar S, Lindner S, Gildehaus FJ, von Ungern-Sternberg B, Baumann K, Tahirovic S, Kleinberger G, Willem M, Haass C, Bartenstein P, Cumming P, Rominger A, Herms J & Brendel M
Asymmetry of Fibrillar Plaque Burden in Amyloid Mouse Models.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2020 Dec, 61 (12) 1825-1831

Bojkova D, Wagner JUG, Shumliakivska M, Aslan GS, Saleem U, Hansen A, Luxán G, Günther S, Pham MD, Krishnan J, Harter PN, Ermel UH, Frangakis AS, Milting H, Zeiher AM, Klingel K, Cinatl J, Dendorfer A, Eschenhagen T, Tschöpe C, Ciesek S & Dimmeler S
SARS-CoV-2 infects and induces cytotoxic effects in human cardiomyocytes.
Cardiovascular research, 2020 Dec 01, 116 (14) 2207-2215

Vettermann FJ, Unterrainer M, Ruf V, Fleischmann DF, Rupprecht R, Forbrig R, Herms J, Tonn JC, Belka C, Bartenstein P, Niyazi M & Albert NL
Dual PET Imaging of an H3K27M-Mutant Glioma With 18F-GE-180 and 18F-FET PET.
Clinical nuclear medicine, 2020 Dec, 45 (12) 992-993

Wenger KJ, Wagner M, Harter PN, Franz K, Bojunga J, Fokas E, Imhoff D, Rödel C, Rieger J, Hattingen E, Steinbach JP, Pilatus U & Voss M
Maintenance of Energy Homeostasis during Calorically Restricted Ketogenic Diet and Fasting-MR-Spectroscopic Insights from the ERGO2 Trial.
Cancers, 2020 Nov 27, 12 (12)

Voss M, Wagner M, von Mettenheim N, Harter PN, Wenger KJ, Franz K, Bojunga J, Vetter M, Gerlach R, Glatzel M, Paulsen F, Hattingen E, Baehr O, Ronellenfitsch MW, Fokas E, Imhoff D, Steinbach JP, Rödel C & Rieger J
ERGO2: A Prospective, Randomized Trial of Calorie-Restricted Ketogenic Diet and Fasting in Addition to Reirradiation for Malignant Glioma.
International journal of radiation oncology, biology, physics, 2020 Nov 15, 108 (4) 987-995

Karschnia P, Teske N, Dorostkar MM, Siller S, Weller J, Baehring JM, Dietrich J, von Baumgarten L, Herms J, Tonn JC & Thon N
Extent and prognostic value of MGMT promotor methylation in glioma WHO grade II.
Scientific reports, 2020 Nov 12, 10 (1) 19758

Beyer L, Nitschmann A, Barthel H, van Eimeren T, Unterrainer M, Sauerbeck J, Marek K, Song M, Palleis C, Respondek G, Hammes J, Barbe MT, Onur Ö, Jessen F, Saur D, Schroeter ML, Rumpf JJ, Rullmann M, Schildan A, Patt M, Neumaier B, Barret O, Madonia J, Russell DS, Stephens AW, Roeber S, Herms J, Bötzel K, Levin J, Classen J, Höglinger GU, Bartenstein P, Villemagne V, Drzezga A, Seibyl J, Sabri O & Brendel M
Early-phase [18F]PI-2620 tau-PET imaging as a surrogate marker of neuronal injury.
European journal of nuclear medicine and molecular imaging, 2020 Nov, 47 (12) 2911-2922

Brendel M, Barthel H, van Eimeren T, Marek K, Beyer L, Song M, Palleis C, Gehmeyr M, Fietzek U, Respondek G, Sauerbeck J, Nitschmann A, Zach C, Hammes J, Barbe MT, Onur O, Jessen F, Saur D, Schroeter ML, Rumpf JJ, Rullmann M, Schildan A, Patt M, Neumaier B, Barret O, Madonia J, Russell DS, Stephens A, Roeber S, Herms J, Bötzel K, Classen J, Bartenstein P, Villemagne V, Levin J, Höglinger GU, Drzezga A, Seibyl J & Sabri O
Assessment of 18F-PI-2620 as a Biomarker in Progressive Supranuclear Palsy.
JAMA neurology, 2020 Nov 01, 77 (11) 1408-1419

Siller S, Egensperger R, Szelenyi A, Tonn JC, Zausinger S & Schichor C
Intraspinal epidermoid and dermoid cysts-tumor resection with multimodal intraoperative neurophysiological monitoring and long-term outcome.
Acta neurochirurgica, 2020 Nov, 162 (11) 2895-2903

Wenger KJ, Richter C, Burger MC, Urban H, Kaulfuss S, Harter PN, Sreeramulu S, Schwalbe H, Steinbach JP, Hattingen E, Bähr O & Pilatus U
Non-Invasive Measurement of Drug and 2-HG Signals Using 19F and 1H MR Spectroscopy in Brain Tumors Treated with the Mutant IDH1 Inhibitor BAY1436032.
Cancers, 2020 Oct 29, 12 (11)

Urban H, Maurer GD, Luger AL, Lorenz NI, Sauer B, Stroh C, Trojan J, Mittelbronn M, Steinbach JP, Harter PN & Ronellenfitsch MW
Cetuximab-Mediated Protection from Hypoxia- Induced Cell Death: Implications for Therapy Sequence in Colorectal Cancer.
Cancers, 2020 Oct 20, 12 (10)

Ammer LM, Vollmann-Zwerenz A, Ruf V, Wetzel CH, Riemenschneider MJ, Albert NL, Beckhove P & Hau P
The Role of Translocator Protein TSPO in Hallmarks of Glioblastoma.
Cancers, 2020 Oct 14, 12 (10)

Dinkelbach L, Südmeyer M, Hartmann CJ, Roeber S, Arzberger T, Felsberg J, Ferrea S, Moldovan AS, Amunts K, Schnitzler A & Caspers S
Somatosensory area 3b is selectively unaffected in corticobasal syndrome: combining MRI and histology.
Neurobiology of aging, 2020 Oct, 94 89-100

Banan R, Stichel D, Bleck A, Hong B, Lehmann U, Suwala A, Reinhardt A, Schrimpf D, Buslei R, Stadelmann C, Ehlert K, Prinz M, Acker T, Schittenhelm J, Kaul D, Schweizer L, Capper D, Harter PN, Etminan N, Jones DTW, Pfister SM, Herold-Mende C, Wick W, Sahm F, von Deimling A, Hartmann C & Reuss DE
Infratentorial IDH-mutant astrocytoma is a distinct subtype.
Acta neuropathologica, 2020 Oct, 140 (4) 569-581

Finck T, Liesche-Starnecker F, Probst M, Bette S, Ruf V, Wendl C, Dorn F, Angstwurm K, Schlegel J, Zimmer C, Wiestler B, Wiesinger I & Bornavirus-Encephalitis Study Group
Bornavirus Encephalitis Shows a Characteristic Magnetic Resonance Phenotype in Humans.
Annals of neurology, 2020 Oct, 88 (4) 723-735

Nibbe L, Jungehülsing M, Röber S, Ripberger G & Oppert M
["Hybrid tracheostomy": a low risk procedure for tracheostomy in COVID-19 patients].
Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2020 Oct, 115 (7) 585-590

Lemos M, Venezia S, Refolo V, Heras-Garvin A, Schmidhuber S, Giese A, Leonov A, Ryazanov S, Griesinger C, Galabova G, Staffler G, Wenning GK & Stefanova N
Targeting α-synuclein by PD03 AFFITOPE® and Anle138b rescues neurodegenerative pathology in a model of multiple system atrophy: clinical relevance.
Translational neurodegeneration, 2020 Sep 24, 9 (1) 38

Ewers M, Biechele G, Suárez-Calvet M, Sacher C, Blume T, Morenas-Rodriguez E, Deming Y, Piccio L, Cruchaga C, Kleinberger G, Shaw L, Trojanowski JQ, Herms J, Dichgans M, Alzheimer's Disease Neuroimaging Initiative (ADNI), Brendel M, Haass C & Franzmeier N
Higher CSF sTREM2 and microglia activation are associated with slower rates of beta-amyloid accumulation.
EMBO molecular medicine, 2020 Sep 07, 12 (9) e12308

Sievers P, Hielscher T, Schrimpf D, Stichel D, Reuss DE, Berghoff AS, Neidert MC, Wirsching HG, Mawrin C, Ketter R, Paulus W, Reifenberger G, Lamszus K, Westphal M, Etminan N, Ratliff M, Herold-Mende C, Pfister SM, Jones DTW, Weller M, Harter PN, Wick W, Preusser M, von Deimling A & Sahm F
CDKN2A/B homozygous deletion is associated with early recurrence in meningiomas.
Acta neuropathologica, 2020 Sep, 140 (3) 409-413

Bohmann FO, Seiler A, Gelhard S, Stolz L, Brill B, Brunkhorst R, Steinmetz H, Harter PN, Mittelbronn M & Foerch C
Blood Pressure Lowering Decreases Intracerebral Hemorrhage Volume and Improves Behavioral Outcomes in Experimental Animals.
Journal of stroke, 2020 Sep, 22 (3) 416-418

Braczynski AK, Gfroerer S, Beschorner R, Harter PN, Baumgarten P, Rolle U & Mittelbronn M
Cholinergic innervation and ganglion cell distribution in Hirschsprung's disease.
BMC pediatrics, 2020 Aug 24, 20 (1) 399

LaClair KD, Zhou Q, Michaelsen M, Wefers B, Brill MS, Janjic A, Rathkolb B, Farny D, Cygan M, de Angelis MH, Wurst W, Neumann M, Enard W, Misgeld T, Arzberger T & Edbauer D
Congenic expression of poly-GA but not poly-PR in mice triggers selective neuron loss and interferon responses found in C9orf72 ALS.
Acta neuropathologica, 2020 Aug, 140 (2) 121-142

Kovacs GG, Lukic MJ, Irwin DJ, Arzberger T, Respondek G, Lee EB, Coughlin D, Giese A, Grossman M, Kurz C, McMillan CT, Gelpi E, Compta Y, van Swieten JC, Laat LD, Troakes C, Al-Sarraj S, Robinson JL, Roeber S, Xie SX, Lee VM, Trojanowski JQ & Höglinger GU
Distribution patterns of tau pathology in progressive supranuclear palsy.
Acta neuropathologica, 2020 Aug, 140 (2) 99-119

Palleis C, Morenas-Rodriguez E, Murcia FJM, Giese A, Nuscher B, Haass C, Höglinger G, Bötzel K & Levin J
Longitudinal correlation between neurofilament light chain and UMSARS in Multiple System Atrophy.
Clinical neurology and neurosurgery, 2020 Aug, 195 105924

Luger AL, Lorenz NI, Urban H, Divé I, Engel AL, Strassheimer F, Dettmer K, Zeiner PS, Shaid S, Struve N, Kriegs M, Hofmann U, Oefner PJ, Harter PN, Steinbach JP & Ronellenfitsch MW
Activation of Epidermal Growth Factor Receptor Sensitizes Glioblastoma Cells to Hypoxia-Induced Cell Death.
Cancers, 2020 Aug 03, 12 (8)

Key J, Harter PN, Sen NE, Gradhand E, Auburger G & Gispert S
Mid-Gestation lethality of Atxn2l-Ablated Mice.
International journal of molecular sciences, 2020 Jul 20, 21 (14)

Eckenweber F, Medina-Luque J, Blume T, Sacher C, Biechele G, Wind K, Deussing M, Briel N, Lindner S, Boening G, von Ungern-Sternberg B, Unterrainer M, Albert NL, Zwergal A, Levin J, Bartenstein P, Cumming P, Rominger A, Höglinger GU, Herms J & Brendel M
Longitudinal TSPO expression in tau transgenic P301S mice predicts increased tau accumulation and deteriorated spatial learning.
Journal of neuroinflammation, 2020 Jul 13, 17 (1) 208

Unterrainer M, Fleischmann DF, Vettermann F, Ruf V, Kaiser L, Nelwan D, Lindner S, Brendel M, Wenter V, Stöcklein S, Herms J, Milenkovic VM, Rupprecht R, Tonn JC, Belka C, Bartenstein P, Niyazi M & Albert NL
TSPO PET, tumour grading and molecular genetics in histologically verified glioma: a correlative 18F-GE-180 PET study.
European journal of nuclear medicine and molecular imaging, 2020 Jun, 47 (6) 1368-1380

Jecmenica Lukic M, Kurz C, Respondek G, Grau-Rivera O, Compta Y, Gelpi E, Troakes C, Barcelona Brain Bank collaborative group, the MDS-endorsed PSP study group, van Swieten JC, Giese A, Roeber S, Arzberger T & Höglinger G
Copathology in Progressive Supranuclear Palsy: Does It Matter?
Movement disorders : official journal of the Movement Disorder Society, 2020 Jun, 35 (6) 984-993

Sebastian Monasor L, Müller SA, Colombo AV, Tanrioever G, König J, Roth S, Liesz A, Berghofer A, Piechotta A, Prestel M, Saito T, Saido TC, Herms J, Willem M, Haass C, Lichtenthaler SF & Tahirovic S
Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models.
eLife, 2020 Jun 08, 9

Ruf VC, Shi S, Schmidt F, Weckbecker D, Nübling GS, Ködel U, Mollenhauer B & Giese A
Potential sources of interference with the highly sensitive detection and quantification of alpha-synuclein seeds by qRT-QuIC.
FEBS open bio, 2020 May, 10 (5) 883-893

Ruf VC, Schöler A, Capper D, Arzberger T, Herms J & Schüller U
An 8-Year-Old Girl with Posterior Fossa Mass.
Brain pathology (Zurich, Switzerland), 2020 May, 30 (3) 713-714

Ronellenfitsch MW, Harter PN, Kirchner M, Heining C, Hutter B, Gieldon L, Schittenhelm J, Schuhmann MU, Tatagiba M, Marquardt G, Wagner M, Endris V, Brandts CH, Mautner VF, Schröck E, Weichert W, Brors B, von Deimling A, Mittelbronn M, Steinbach JP, Reuss DE, Glimm H, Stenzinger A & Fröhling S
Targetable ERBB2 mutations identified in neurofibroma/schwannoma hybrid nerve sheath tumors.
The Journal of clinical investigation, 2020 May 01, 130 (5) 2488-2495

Khosravi B, LaClair KD, Riemenschneider H, Zhou Q, Frottin F, Mareljic N, Czuppa M, Farny D, Hartmann H, Michaelsen M, Arzberger T, Hartl FU, Hipp MS & Edbauer D
Cell-to-cell transmission of C9orf72 poly-(Gly-Ala) triggers key features of ALS/FTD.
The EMBO journal, 2020 Apr 15, 39 (8) e102811

Niller HH, Angstwurm K, Rubbenstroth D, Schlottau K, Ebinger A, Giese S, Wunderlich S, Banas B, Forth LF, Hoffmann D, Höper D, Schwemmle M, Tappe D, Schmidt-Chanasit J, Nobach D, Herden C, Brochhausen C, Velez-Char N, Mamilos A, Utpatel K, Evert M, Zoubaa S, Riemenschneider MJ, Ruf V, Herms J, Rieder G, Errath M, Matiasek K, Schlegel J, Liesche-Starnecker F, Neumann B, Fuchs K, Linker RA, Salzberger B, Freilinger T, Gartner L, Wenzel JJ, Reischl U, Jilg W, Gessner A, Jantsch J, Beer M & Schmidt B
Zoonotic spillover infections with Borna disease virus 1 leading to fatal human encephalitis, 1999-2019: an epidemiological investigation.
The Lancet. Infectious diseases, 2020 Apr, 20 (4) 467-477

Nuebling GS, Plesch E, Ruf VC, Högen T, Lorenzl S, Kamp F, Giese A & Levin J
Binding of Metal-Ion-Induced Tau Oligomers to Lipid Surfaces Is Enhanced by GSK-3β-Mediated Phosphorylation.
ACS chemical neuroscience, 2020 Mar 18, 11 (6) 880-887

Maurer A, Leonov A, Ryazanov S, Herfert K, Kuebler L, Buss S, Schmidt F, Weckbecker D, Linder R, Bender D, Giese A, Pichler BJ & Griesinger C
11 C Radiolabeling of anle253b: a Putative PET Tracer for Parkinson's Disease That Binds to α-Synuclein Fibrils in vitro and Crosses the Blood-Brain Barrier.
ChemMedChem, 2020 Mar 05, 15 (5) 411-415

Osterman A, Ruf VC, Domingo C, Nitsche A, Eichhorn P, Zimmermann H, Seelos K, Zange S, Dimitriadis K, Pfister HW, Thye T, Giese A, Tappe D & Böhm S
Travel-associated neurological disease terminated in a postmortem diagnosed atypical HSV-1 encephalitis after high-dose steroid therapy - a case report.
BMC infectious diseases, 2020 Feb 18, 20 (1) 150

Zhou Q, Mareljic N, Michaelsen M, Parhizkar S, Heindl S, Nuscher B, Farny D, Czuppa M, Schludi C, Graf A, Krebs S, Blum H, Feederle R, Roth S, Haass C, Arzberger T, Liesz A & Edbauer D
Active poly-GA vaccination prevents microglia activation and motor deficits in a C9orf72 mouse model.
EMBO molecular medicine, 2020 Feb 07, 12 (2) e10919

Chakroun T, Evsyukov V, Nykänen NP, Höllerhage M, Schmidt A, Kamp F, Ruf VC, Wurst W, Rösler TW & Höglinger GU
Alpha-synuclein fragments trigger distinct aggregation pathways.
Cell death & disease, 2020 Feb 03, 11 (2) 84

Tan Y, Sgobio C, Arzberger T, Machleid F, Tang Q, Findeis E, Tost J, Chakroun T, Gao P, Höllerhage M, Bötzel K, Herms J, Höglinger G & Koeglsperger T
Loss of fragile X mental retardation protein precedes Lewy pathology in Parkinson's disease.
Acta neuropathologica, 2020 Feb, 139 (2) 319-345

Neumann JE, Spohn M, Obrecht D, Mynarek M, Thomas C, Hasselblatt M, Dorostkar MM, Wefers AK, Frank S, Monoranu CM, Koch A, Witt H, Kool M, Pajtler KW, Rutkowski S, Glatzel M & Schüller U
Molecular characterization of histopathological ependymoma variants.
Acta neuropathologica, 2020 Feb, 139 (2) 305-318

Camilleri A, Ghio S, Caruana M, Weckbecker D, Schmidt F, Kamp F, Leonov A, Ryazanov S, Griesinger C, Giese A, Cauchi RJ & Vassallo N
Tau-induced mitochondrial membrane perturbation is dependent upon cardiolipin.
Biochimica et biophysica acta. Biomembranes, 2020 Feb 01, 1862 (2) 183064

Nihei Y, Mori K, Werner G, Arzberger T, Zhou Q, Khosravi B, Japtok J, Hermann A, Sommacal A, Weber M, German Consortium for Frontotemporal Lobar Degeneration, Bavarian Brain Banking Alliance, Kamp F, Nuscher B, Edbauer D & Haass C
Poly-glycine-alanine exacerbates C9orf72 repeat expansion-mediated DNA damage via sequestration of phosphorylated ATM and loss of nuclear hnRNPA3.
Acta neuropathologica, 2020 Jan, 139 (1) 99-118

Respondek G, Grimm MJ, Piot I, Arzberger T, Compta Y, Englund E, Ferguson LW, Gelpi E, Roeber S, Giese A, Grossman M, Irwin DJ, Meissner WG, Nilsson C, Pantelyat A, Rajput A, van Swieten JC, Troakes C, Höglinger GU & Movement Disorder Society-Endorsed Progressive Supranuclear Palsy Study Group
Validation of the movement disorder society criteria for the diagnosis of 4-repeat tauopathies.
Movement disorders : official journal of the Movement Disorder Society, 2020 Jan, 35 (1) 171-176

Braczynski AK, Capper D, Jones DTW, Schittenhelm J, Stichel D, von Deimling A, Harter PN & Mittelbronn M
High density DNA methylation array is a reliable alternative for PCR-based analysis of the MGMT promoter methylation status in glioblastoma.
Pathology, research and practice, 2020 Jan, 216 (1) 152728

Nörenberg D, Schmidt F, Schinke K, Frenzel T, Pietsch H, Giese A, Ertl-Wagner B & Levin J
Investigation of potential adverse central nervous system effects after long term oral administration of gadolinium in mice.
PloS one, 2020, 15 (4) e0231495

Unger K, Fleischmann DF, Ruf V, Felsberg J, Piehlmaier D, Samaga D, Hess J, Suresh MP, Mittelbronn M, Lauber K, Budach W, Sabel M, Rödel C, Reifenberger G, Herms J, Tonn JC, Zitzelsberger H, Belka C & Niyazi M
Improved risk stratification in younger IDH wild-type glioblastoma patients by combining a 4-miRNA signature with MGMT promoter methylation status.
Neuro-oncology advances, 2020, 2 (1) vdaa137

2019

Saravanan MS, Ryazanov S, Leonov A, Nicolai J, Praest P, Giese A, Winter R, Khemtemourian L, Griesinger C & Killian JA
The small molecule inhibitor anle145c thermodynamically traps human islet amyloid peptide in the form of non-cytotoxic oligomers.
Scientific reports, 2019 Dec 13, 9 (1) 19023

Ghasemi DR, Sill M, Okonechnikov K, Korshunov A, Yip S, Schutz PW, Scheie D, Kruse A, Harter PN, Kastelan M, Wagner M, Hartmann C, Benzel J, Maass KK, Khasraw M, Sträter R, Thomas C, Paulus W, Kratz CP, Witt H, Kawauchi D, Herold-Mende C, Sahm F, Brandner S, Kool M, Jones DTW, von Deimling A, Pfister SM, Reuss DE & Pajtler KW
MYCN amplification drives an aggressive form of spinal ependymoma.
Acta neuropathologica, 2019 Dec, 138 (6) 1075-1089

Di Tacchio M, Macas J, Weissenberger J, Sommer K, Bähr O, Steinbach JP, Senft C, Seifert V, Glas M, Herrlinger U, Krex D, Meinhardt M, Weyerbrock A, Timmer M, Goldbrunner R, Deckert M, Scheel AH, Büttner R, Grauer OM, Schittenhelm J, Tabatabai G, Harter PN, Günther S, Devraj K, Plate KH & Reiss Y
Tumor Vessel Normalization, Immunostimulatory Reprogramming, and Improved Survival in Glioblastoma with Combined Inhibition of PD-1, Angiopoietin-2, and VEGF.
Cancer immunology research, 2019 Dec, 7 (12) 1910-1927

Blumenstock S, Angelo MF, Peters F, Dorostkar MM, Ruf VC, Luckner M, Crux S, Slapakova L, Arzberger T, Claverol S, Herzog E & Herms J
Early defects in translation elongation factor 1α levels at excitatory synapses in α-synucleinopathy.
Acta neuropathologica, 2019 Dec, 138 (6) 971-986

Sacher C, Blume T, Beyer L, Peters F, Eckenweber F, Sgobio C, Deussing M, Albert NL, Unterrainer M, Lindner S, Gildehaus FJ, von Ungern-Sternberg B, Brzak I, Neumann U, Saito T, Saido TC, Bartenstein P, Rominger A, Herms J & Brendel M
Longitudinal PET Monitoring of Amyloidosis and Microglial Activation in a Second-Generation Amyloid-β Mouse Model.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2019 Dec, 60 (12) 1787-1793

Biczok A, Jungk C, Egensperger R, von Deimling A, Suchorska B, Tonn JC, Herold-Mende C & Schichor C
Microscopic brain invasion in meningiomas previously classified as WHO grade I is not associated with patient outcome.
Journal of neuro-oncology, 2019 Dec, 145 (3) 469-477

Peters F, Salihoglu H, Pratsch K, Herzog E, Pigoni M, Sgobio C, Lichtenthaler SF, Neumann U & Herms J
Tau deletion reduces plaque-associated BACE1 accumulation and decelerates plaque formation in a mouse model of Alzheimer's disease.
The EMBO journal, 2019 Dec 02, 38 (23) e102345

Zeiner PS, Kinzig M, Divé I, Maurer GD, Filipski K, Harter PN, Senft C, Bähr O, Hattingen E, Steinbach JP, Sörgel F, Voss M, Steidl E & Ronellenfitsch MW
Regorafenib CSF Penetration, Efficacy, and MRI Patterns in Recurrent Malignant Glioma Patients.
Journal of clinical medicine, 2019 Nov 21, 8 (12)

Cali CP, Patino M, Tai YK, Ho WY, McLean CA, Morris CM, Seeley WW, Miller BL, Gaig C, Vonsattel JPG, White CL, Roeber S, Kretzschmar H, Troncoso JC, Troakes C, Gearing M, Ghetti B, Van Deerlin VM, Lee VM, Trojanowski JQ, Mok KY, Ling H, Dickson DW, Schellenberg GD, Ling SC & Lee EB
C9orf72 intermediate repeats are associated with corticobasal degeneration, increased C9orf72 expression and disruption of autophagy.
Acta neuropathologica, 2019 Nov, 138 (5) 795-811

Vettermann F, Suchorska B, Unterrainer M, Nelwan D, Forbrig R, Ruf V, Wenter V, Kreth FW, Herms J, Bartenstein P, Tonn JC & Albert NL
Non-invasive prediction of IDH-wildtype genotype in gliomas using dynamic 18F-FET PET.
European journal of nuclear medicine and molecular imaging, 2019 Nov, 46 (12) 2581-2589

Unterrainer M, Ruf V, Cyran CC, Brendel M, Thon N, Herms J, Schüller U, Tonn JC, Bartenstein P & Albert NL
Identification of Distant Metastases From Recurrent Gliosarcoma Using Whole-Body 18F-FDG PET/CT.
Clinical nuclear medicine, 2019 Nov, 44 (11) 923-924

Bernatz S, Ilina EI, Devraj K, Harter PN, Mueller K, Kleber S, Braun Y, Penski C, Renner C, Halder R, Jennewein L, Solbach C, Thorsen F, Pestalozzi BC, Mischo A & Mittelbronn M
Impact of Docetaxel on blood-brain barrier function and formation of breast cancer brain metastases.
Journal of experimental & clinical cancer research : CR, 2019 Oct 29, 38 (1) 434

Liesche F, Ruf V, Zoubaa S, Kaletka G, Rosati M, Rubbenstroth D, Herden C, Goehring L, Wunderlich S, Wachter MF, Rieder G, Lichtmannegger I, Permanetter W, Heckmann JG, Angstwurm K, Neumann B, Märkl B, Haschka S, Niller HH, Schmidt B, Jantsch J, Brochhausen C, Schlottau K, Ebinger A, Hemmer B, Riemenschneider MJ, Herms J, Beer M, Matiasek K & Schlegel J
The neuropathology of fatal encephalomyelitis in human Borna virus infection.
Acta neuropathologica, 2019 Oct, 138 (4) 653-665

Wegrzynowicz M, Bar-On D, Calo' L, Anichtchik O, Iovino M, Xia J, Ryazanov S, Leonov A, Giese A, Dalley JW, Griesinger C, Ashery U & Spillantini MG
Depopulation of dense α-synuclein aggregates is associated with rescue of dopamine neuron dysfunction and death in a new Parkinson's disease model.
Acta neuropathologica, 2019 Oct, 138 (4) 575-595

Russo A, Paret C, Alt F, Burhenne J, Fresnais M, Wagner W, Glaser M, Bender H, Huprich S, Harter PN, Filipski K, Lehmann N, Backes N, Roth L, Seidmann L, Sommer C, Brockmann MA, Pietsch T, Neu MA, Wingerter A & Faber J
Ceritinib-Induced Regression of an Insulin-Like Growth Factor-Driven Neuroepithelial Brain Tumor.
International journal of molecular sciences, 2019 Aug 30, 20 (17)

Ghio S, Camilleri A, Caruana M, Ruf VC, Schmidt F, Leonov A, Ryazanov S, Griesinger C, Cauchi RJ, Kamp F, Giese A & Vassallo N
Cardiolipin Promotes Pore-Forming Activity of Alpha-Synuclein Oligomers in Mitochondrial Membranes.
ACS chemical neuroscience, 2019 Aug 21, 10 (8) 3815-3829

Brendel M, Deussing M, Blume T, Kaiser L, Probst F, Overhoff F, Peters F, von Ungern-Sternberg B, Ryazanov S, Leonov A, Griesinger C, Zwergal A, Levin J, Bartenstein P, Yakushev I, Cumming P, Boening G, Ziegler S, Herms J, Giese A & Rominger A
Late-stage Anle138b treatment ameliorates tau pathology and metabolic decline in a mouse model of human Alzheimer's disease tau.
Alzheimer's research & therapy, 2019 Aug 01, 11 (1) 67

Filipski K, Braun Y, Zinke J, Roller B, Baumgarten P, Wagner M, Senft C, Zeiner PS, Ronellenfitsch MW, Steinbach JP, Plate KH, Gasparoni G, Mittelbronn M, Capper D & Harter PN
Lack of H3K27 trimethylation is associated with 1p/19q codeletion in diffuse gliomas.
Acta neuropathologica, 2019 Aug, 138 (2) 331-334

Grimm MJ, Respondek G, Stamelou M, Arzberger T, Ferguson L, Gelpi E, Giese A, Grossman M, Irwin DJ, Pantelyat A, Rajput A, Roeber S, van Swieten JC, Troakes C, Antonini A, Bhatia KP, Colosimo C, van Eimeren T, Kassubek J, Levin J, Meissner WG, Nilsson C, Oertel WH, Piot I, Poewe W, Wenning GK, Boxer A, Golbe LI, Josephs KA, Litvan I, Morris HR, Whitwell JL, Compta Y, Corvol JC, Lang AE, Rowe JB, Höglinger GU & Movement Disorder Society-endorsed PSP Study Group
How to apply the movement disorder society criteria for diagnosis of progressive supranuclear palsy.
Movement disorders : official journal of the Movement Disorder Society, 2019 Aug, 34 (8) 1228-1232

Levin J, Maaß S, Schuberth M, Giese A, Oertel WH, Poewe W, Trenkwalder C, Wenning GK, Mansmann U, Südmeyer M, Eggert K, Mollenhauer B, Lipp A, Löhle M, Classen J, Münchau A, Kassubek J, Gandor F, Berg D, Egert-Schwender S, Eberhardt C, Paul F, Bötzel K, Ertl-Wagner B, Huppertz HJ, Ricard I, Höglinger GU & PROMESA Study Group
Safety and efficacy of epigallocatechin gallate in multiple system atrophy (PROMESA): a randomised, double-blind, placebo-controlled trial.
The Lancet. Neurology, 2019 Aug, 18 (8) 724-735

Zeiner PS, Preusse C, Golebiewska A, Zinke J, Iriondo A, Muller A, Kaoma T, Filipski K, Müller-Eschner M, Bernatz S, Blank AE, Baumgarten P, Ilina E, Grote A, Hansmann ML, Verhoff MA, Franz K, Feuerhake F, Steinbach JP, Wischhusen J, Stenzel W, Niclou SP, Harter PN & Mittelbronn M
Distribution and prognostic impact of microglia/macrophage subpopulations in gliomas.
Brain pathology (Zurich, Switzerland), 2019 Jul, 29 (4) 513-529

Bartoletti-Stella A, Corrado P, Mometto N, Baiardi S, Durrenberger PF, Arzberger T, Reynolds R, Kretzschmar H, Capellari S & Parchi P
Analysis of RNA Expression Profiles Identifies Dysregulated Vesicle Trafficking Pathways in Creutzfeldt-Jakob Disease.
Molecular neurobiology, 2019 Jul, 56 (7) 5009-5024

Bartels M, Weckbecker D, Kuhn PH, Ryazanov S, Leonov A, Griesinger C, Lichtenthaler SF, Bötzel K & Giese A
Iron-mediated aggregation and toxicity in a novel neuronal cell culture model with inducible alpha-synuclein expression.
Scientific reports, 2019 Jun 24, 9 (1) 9100

Vewinger N, Huprich S, Seidmann L, Russo A, Alt F, Bender H, Sommer C, Samuel D, Lehmann N, Backes N, Roth L, Harter PN, Filipski K, Faber J & Paret C
IGF1R Is a Potential New Therapeutic Target for HGNET-BCOR Brain Tumor Patients.
International journal of molecular sciences, 2019 Jun 21, 20 (12)

Pottier C, Ren Y, Perkerson RB, Baker M, Jenkins GD, van Blitterswijk M, DeJesus-Hernandez M, van Rooij JGJ, Murray ME, Christopher E, McDonnell SK, Fogarty Z, Batzler A, Tian S, Vicente CT, Matchett B, Karydas AM, Hsiung GR, Seelaar H, Mol MO, Finger EC, Graff C, Öijerstedt L, Neumann M, Heutink P, Synofzik M, Wilke C, Prudlo J, Rizzu P, Simon-Sanchez J, Edbauer D, Roeber S, Diehl-Schmid J, Evers BM, King A, Mesulam MM, Weintraub S, Geula C, Bieniek KF, Petrucelli L, Ahern GL, Reiman EM, Woodruff BK, Caselli RJ, Huey ED, Farlow MR, Grafman J, Mead S, Grinberg LT, Spina S, Grossman M, Irwin DJ, Lee EB, Suh E, Snowden J, Mann D, Ertekin-Taner N, Uitti RJ, Wszolek ZK, Josephs KA, Parisi JE, Knopman DS, Petersen RC, Hodges JR, Piguet O, Geier EG, Yokoyama JS, Rissman RA, Rogaeva E, Keith J, Zinman L, Tartaglia MC, Cairns NJ, Cruchaga C, Ghetti B, Kofler J, Lopez OL, Beach TG, Arzberger T, Herms J, Honig LS, Vonsattel JP, Halliday GM, Kwok JB, White CL, Gearing M, Glass J, Rollinson S, Pickering-Brown S, Rohrer JD, Trojanowski JQ, Van Deerlin V, Bigio EH, Troakes C, Al-Sarraj S, Asmann Y, Miller BL, Graff-Radford NR, Boeve BF, Seeley WW, Mackenzie IRA, van Swieten JC, Dickson DW, Biernacka JM & Rademakers R
Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD.
Acta neuropathologica, 2019 Jun, 137 (6) 879-899

van Well EM, Bader V, Patra M, Sánchez-Vicente A, Meschede J, Furthmann N, Schnack C, Blusch A, Longworth J, Petrasch-Parwez E, Mori K, Arzberger T, Trümbach D, Angersbach L, Showkat C, Sehr DA, Berlemann LA, Goldmann P, Clement AM, Behl C, Woerner AC, Saft C, Wurst W, Haass C, Ellrichmann G, Gold R, Dittmar G, Hipp MS, Hartl FU, Tatzelt J & Winklhofer KF
A protein quality control pathway regulated by linear ubiquitination.
The EMBO journal, 2019 May 02, 38 (9)

Eberherr C, Beck A, Vokuhl C, Becker K, Häberle B, Von Schweinitz D & Kappler R
Targeting excessive MYCN expression using MLN8237 and JQ1 impairs the growth of hepatoblastoma cells.
International journal of oncology, 2019 May, 54 (5) 1853-1863

Montagna E, Crux S, Luckner M, Herber J, Colombo AV, Marinković P, Tahirovic S, Lichtenthaler SF, Wanner G, Müller UC, Sgobio C & Herms J
In vivo Ca2+ imaging of astrocytic microdomains reveals a critical role of the amyloid precursor protein for mitochondria.
Glia, 2019 May, 67 (5) 985-998

Mastrella G, Hou M, Li M, Stoecklein VM, Zdouc N, Volmar MNM, Miletic H, Reinhard S, Herold-Mende CC, Kleber S, Eisenhut K, Gargiulo G, Synowitz M, Vescovi AL, Harter PN, Penninger JM, Wagner E, Mittelbronn M, Bjerkvig R, Hambardzumyan D, Schüller U, Tonn JC, Radke J, Glass R & Kälin RE
Targeting APLN/APLNR Improves Antiangiogenic Efficiency and Blunts Proinvasive Side Effects of VEGFA/VEGFR2 Blockade in Glioblastoma.
Cancer research, 2019 May 01, 79 (9) 2298-2313

Unterrainer M, Ruf V, Ilhan H, Vettermann FJ, Cyran CC, Niyazi M, Bartenstein P, Tonn JC & Albert NL
68Ga-DOTATOC PET/CT Differentiates Meningioma From Dural Metastases.
Clinical nuclear medicine, 2019 May, 44 (5) 412-413

Burgold J, Schulz-Trieglaff EK, Voelkl K, Gutiérrez-Ángel S, Bader JM, Hosp F, Mann M, Arzberger T, Klein R, Liebscher S & Dudanova I
Cortical circuit alterations precede motor impairments in Huntington's disease mice.
Scientific reports, 2019 Apr 29, 9 (1) 6634

Sundstrøm T, Prestegarden L, Azuaje F, Aasen SN, Røsland GV, Varughese JK, Bahador M, Bernatz S, Braun Y, Harter PN, Skaftnesmo KO, Ingham ES, Mahakian LM, Tam S, Tepper CG, Petersen K, Ferrara KW, Tronstad KJ, Lund-Johansen M, Beschorner R, Bjerkvig R & Thorsen F
Inhibition of mitochondrial respiration prevents BRAF-mutant melanoma brain metastasis.
Acta neuropathologica communications, 2019 Apr 10, 7 (1) 55

Liu J, Heinsen H, Grinberg LT, Alho E, Amaro E, Pasqualucci CA, Rüb U, Seidel K, den Dunnen W, Arzberger T, Schmitz C, Kiessling MC, Bader B & Danek A
Pathoarchitectonics of the cerebral cortex in chorea-acanthocytosis and Huntington's disease.
Neuropathology and applied neurobiology, 2019 Apr, 45 (3) 230-243

Delaidelli A, Jan A, Herms J & Sorensen PH
Translational control in brain pathologies: biological significance and therapeutic opportunities.
Acta neuropathologica, 2019 Apr, 137 (4) 535-555

Focke C, Blume T, Zott B, Shi Y, Deussing M, Peters F, Schmidt C, Kleinberger G, Lindner S, Gildehaus FJ, Beyer L, von Ungern-Sternberg B, Bartenstein P, Ozmen L, Baumann K, Dorostkar MM, Haass C, Adelsberger H, Herms J, Rominger A & Brendel M
Early and Longitudinal Microglial Activation but Not Amyloid Accumulation Predicts Cognitive Outcome in PS2APP Mice.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2019 Apr, 60 (4) 548-554

Baiardi S, Redaelli V, Ripellino P, Rossi M, Franceschini A, Moggio M, Sola P, Ladogana A, Fociani P, Magherini A, Capellari S, Giese A, Caughey B, Caroppo P & Parchi P
Prion-related peripheral neuropathy in sporadic Creutzfeldt-Jakob disease.
Journal of neurology, neurosurgery, and psychiatry, 2019 Apr, 90 (4) 424-427

Marinković P, Blumenstock S, Goltstein PM, Korzhova V, Peters F, Knebl A & Herms J
In vivo imaging reveals reduced activity of neuronal circuits in a mouse tauopathy model.
Brain : a journal of neurology, 2019 Apr 01, 142 (4) 1051-1062

Midani-Kurçak JS, Dinekov M, Puladi B, Arzberger T & Köhler C
Effect of tau-pathology on charged multivesicular body protein 2b (CHMP2B).
Brain research, 2019 Mar 01, 1706 224-236

Forster MT, Baumgarten P, Gessler F, Maurer G, Senft C, Hattingen E, Seifert V, Harter PN & Franz K
Influence of pregnancy on glioma patients.
Acta neurochirurgica, 2019 Mar, 161 (3) 535-543

Foltyn M, Luger AL, Lorenz NI, Sauer B, Mittelbronn M, Harter PN, Steinbach JP & Ronellenfitsch MW
The physiological mTOR complex 1 inhibitor DDIT4 mediates therapy resistance in glioblastoma.
British journal of cancer, 2019 Mar, 120 (5) 481-487

Unterrainer M, Fleischmann DF, Diekmann C, Vomacka L, Lindner S, Vettermann F, Brendel M, Wenter V, Ertl-Wagner B, Herms J, Wetzel C, Rupprecht R, Tonn JC, Belka C, Bartenstein P, Niyazi M & Albert NL
Comparison of 18F-GE-180 and dynamic 18F-FET PET in high grade glioma: a double-tracer pilot study.
European journal of nuclear medicine and molecular imaging, 2019 Mar, 46 (3) 580-590

Yin C, Ackermann S, Ma Z, Mohanta SK, Zhang C, Li Y, Nietzsche S, Westermann M, Peng L, Hu D, Bontha SV, Srikakulapu P, Beer M, Megens RTA, Steffens S, Hildner M, Halder LD, Eckstein HH, Pelisek J, Herms J, Roeber S, Arzberger T, Borodovsky A, Habenicht L, Binder CJ, Weber C, Zipfel PF, Skerka C & Habenicht AJR
ApoE attenuates unresolvable inflammation by complex formation with activated C1q.
Nature medicine, 2019 Mar, 25 (3) 496-506

Bruns I, Sauer B, Burger MC, Eriksson J, Hofmann U, Braun Y, Harter PN, Luger AL, Ronellenfitsch MW, Steinbach JP & Rieger J
Disruption of peroxisome proliferator-activated receptor γ coactivator (PGC)-1α reverts key features of the neoplastic phenotype of glioma cells.
The Journal of biological chemistry, 2019 Mar 01, 294 (9) 3037-3050

Linder B, Weirauch U, Ewe A, Uhmann A, Seifert V, Mittelbronn M, Harter PN, Aigner A & Kögel D
Therapeutic Targeting of Stat3 Using Lipopolyplex Nanoparticle-Formulated siRNA in a Syngeneic Orthotopic Mouse Glioma Model.
Cancers, 2019 Mar 08, 11 (3)

Yin C, Ackermann S, Ma Z, Mohanta SK, Zhang C, Li Y, Nietzsche S, Westermann M, Peng L, Hu D, Bontha SV, Srikakulapu P, Beer M, Megens RTA, Steffens S, Hildner M, Halder LD, Eckstein HH, Pelisek J, Herms J, Roeber S, Arzberger T, Borodovsky A, Habenicht L, Binder CJ, Weber C, Zipfel PF, Skerka C & Habenicht AJR
Publisher Correction: ApoE attenuates unresolvable inflammation by complex formation with activated C1q.
Nature medicine, 2019 Mar, 25 (3) 529

Eisemann T, Costa B, Harter PN, Wick W, Mittelbronn M, Angel P & Peterziel H
Podoplanin expression is a prognostic biomarker but may be dispensable for the malignancy of glioblastoma.
Neuro-oncology, 2019 Feb 19, 21 (3) 326-336

Kunz M, Albert NL, Unterrainer M, la Fougere C, Egensperger R, Schüller U, Lutz J, Kreth S, Tonn JC, Kreth FW & Thon N
Dynamic 18F-FET PET is a powerful imaging biomarker in gadolinium-negative gliomas.
Neuro-oncology, 2019 Feb 14, 21 (2) 274-284

Heras-Garvin A, Weckbecker D, Ryazanov S, Leonov A, Griesinger C, Giese A, Wenning GK & Stefanova N
Anle138b modulates α-synuclein oligomerization and prevents motor decline and neurodegeneration in a mouse model of multiple system atrophy.
Movement disorders : official journal of the Movement Disorder Society, 2019 Feb, 34 (2) 255-263

Borggraefe I, Tacke M, Gerstl L, Leiz S, Coras R, Blümcke I, Giese A, Ertl-Wagner B, Thiel CT, Noachtar S & Peraud A
Epilepsy surgery in the first months of life: a large type IIb focal cortical dysplasia causing neonatal drug-resistant epilepsy.
Epileptic disorders : international epilepsy journal with videotape, 2019 Feb 01, 21 (1) 122-127

Parhizkar S, Arzberger T, Brendel M, Kleinberger G, Deussing M, Focke C, Nuscher B, Xiong M, Ghasemigharagoz A, Katzmarski N, Krasemann S, Lichtenthaler SF, Müller SA, Colombo A, Monasor LS, Tahirovic S, Herms J, Willem M, Pettkus N, Butovsky O, Bartenstein P, Edbauer D, Rominger A, Ertürk A, Grathwohl SA, Neher JJ, Holtzman DM, Meyer-Luehmann M & Haass C
Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE.
Nature neuroscience, 2019 Feb, 22 (2) 191-204

Burger MC, Zhang C, Harter PN, Romanski A, Strassheimer F, Senft C, Tonn T, Steinbach JP & Wels WS
CAR-Engineered NK Cells for the Treatment of Glioblastoma: Turning Innate Effectors Into Precision Tools for Cancer Immunotherapy.
Frontiers in immunology, 2019, 10 2683

Suchorska B, Schüller U, Biczok A, Lenski M, Albert NL, Giese A, Kreth FW, Ertl-Wagner B, Tonn JC & Ingrisch M
Contrast enhancement is a prognostic factor in IDH1/2 mutant, but not in wild-type WHO grade II/III glioma as confirmed by machine learning.
European journal of cancer (Oxford, England : 1990), 2019 Jan, 107 15-27

Gessler F, Bernstock JD, Braczynski A, Lescher S, Baumgarten P, Harter PN, Mittelbronn M, Wu T, Seifert V & Senft C
Surgery for Glioblastoma in Light of Molecular Markers: Impact of Resection and MGMT Promoter Methylation in Newly Diagnosed IDH-1 Wild-Type Glioblastomas.
Neurosurgery, 2019 Jan 01, 84 (1) 190-197

Wenger KJ, Hattingen E, Harter PN, Richter C, Franz K, Steinbach JP, Bähr O & Pilatus U
Fitting algorithms and baseline correction influence the results of non-invasive in vivo quantitation of 2-hydroxyglutarate with 1 H-MRS.
NMR in biomedicine, 2019 Jan, 32 (1) e4027

Prokopenko I, Miyakawa G, Zheng B, Heikkinen J, Petrova Quayle D, Udeh-Momoh C, Claringbould A, Neumann J, Haytural H, Kaakinen MA, Loizidou E, Meissner E, Bertram L, BIOS consortium, Gveric DO, Gentleman SM, Attems J, Perneczky R, Arzberger T, Muglia P, Lill CM, Parkkinen L & Middleton LT
Alzheimer's disease pathology explains association between dementia with Lewy bodies and APOE-ε4/TOMM40 long poly-T repeat allele variants.
Alzheimer's & dementia (New York, N. Y.), 2019, 5 814-824

Mukherjee S, Klaus C, Pricop-Jeckstadt M, Miller JA & Struebing FL
A Microglial Signature Directing Human Aging and Neurodegeneration-Related Gene Networks.
Frontiers in neuroscience, 2019, 13 2

2018

Sievers P, Stichel D, Hielscher T, Schrimpf D, Reinhardt A, Wefers AK, Reuss D, Jones DTW, Bewerunge-Hudler M, Hartmann C, Baumgarten P, Wirsching HG, Winther-Kristensen B, Brokinkel B, Ketter R, Idoate Gastearena MA, Lamszus K, Seiz-Rosenhagen M, Mawrin C, Harter PN, Felsberg J, Hänggi D, Herold-Mende C, Berghoff AS, Weller M, Pfister SM, Wick W, Reifenberger G, Preusser M, von Deimling A & Sahm F
Chordoid meningiomas can be sub-stratified into prognostically distinct DNA methylation classes and are enriched for heterozygous deletions of chromosomal arm 2p.
Acta neuropathologica, 2018 Dec, 136 (6) 975-978

Arzberger T, Pihlstrøm L, Schottlaender L, Chelban V, Houlden H & MSA Exome Consortium
LRP10 in α-synucleinopathies.
The Lancet. Neurology, 2018 Dec, 17 (12) 1033-1034

Mahler C, Unterrainer M, Muth C, Egensperger R, Vomacka L, Lindner S, Ertl-Wagner B, Patzig M, Bartenstein P, Albert N, Kerschensteiner M & Kümpfel T
Imaging microglial activation in tacrolimus-associated CNS vasculitis with translocator protein PET.
Neurology, 2018 Nov 13, 91 (20) 936-937

Blume T, Focke C, Peters F, Deussing M, Albert NL, Lindner S, Gildehaus FJ, von Ungern-Sternberg B, Ozmen L, Baumann K, Bartenstein P, Rominger A, Herms J & Brendel M
Microglial response to increasing amyloid load saturates with aging: a longitudinal dual tracer in vivo μPET-study.
Journal of neuroinflammation, 2018 Nov 06, 15 (1) 307

Unterrainer M, Diekmann C, Dorostkar M, Vettermann FJ, Kümpfel T, Tonn JC, Bartenstein P & Albert NL
Neurosarcoidosis Mimics High-Grade Glioma in Dynamic 18F-FET PET Due to LAT Expression.
Clinical nuclear medicine, 2018 Nov, 43 (11) 840-841

Böck J, Remmele CW, Dittrich M, Müller T, Kondova I, Persengiev S, Bontrop RE, Ade CP, Kraus TFJ, Giese A, El Hajj N, Schneider E & Haaf T
Cell Type and Species-specific Patterns in Neuronal and Non-neuronal Methylomes of Human and Chimpanzee Cortices.
Cerebral cortex (New York, N.Y. : 1991), 2018 Oct 01, 28 (10) 3724-3739

Zhu K, Peters F, Filser S & Herms J
Consequences of Pharmacological BACE Inhibition on Synaptic Structure and Function.
Biological psychiatry, 2018 Oct 01, 84 (7) 478-487

Franceschini A, Strammiello R, Capellari S, Giese A & Parchi P
Regional pattern of microgliosis in sporadic Creutzfeldt-Jakob disease in relation to phenotypic variants and disease progression.
Neuropathology and applied neurobiology, 2018 Oct, 44 (6) 574-589

Rammes G, Seeser F, Mattusch K, Zhu K, Haas L, Kummer M, Heneka M, Herms J & Parsons CG
The NMDA receptor antagonist Radiprodil reverses the synaptotoxic effects of different amyloid-beta (Aβ) species on long-term potentiation (LTP).
Neuropharmacology, 2018 Sep 15, 140 184-192

Abu-Rumeileh S, Redaelli V, Baiardi S, Mackenzie G, Windl O, Ritchie DL, Didato G, Hernandez-Vara J, Rossi M, Capellari S, Imperiale D, Rizzone MG, Belotti A, Sorbi S, Rozemuller AJM, Cortelli P, Gelpi E, Will RG, Zerr I, Giaccone G & Parchi P
Sporadic Fatal Insomnia in Europe: Phenotypic Features and Diagnostic Challenges.
Annals of neurology, 2018 Sep, 84 (3) 347-360

Dudvarski Stanković N, Bicker F, Keller S, Jones DT, Harter PN, Kienzle A, Gillmann C, Arnold P, Golebiewska A, Keunen O, Giese A, von Deimling A, Bäuerle T, Niclou SP, Mittelbronn M, Ye W, Pfister SM & Schmidt MHH
EGFL7 enhances surface expression of integrin α5β1 to promote angiogenesis in malignant brain tumors.
EMBO molecular medicine, 2018 Sep, 10 (9)

Xiang X, Piers TM, Wefers B, Zhu K, Mallach A, Brunner B, Kleinberger G, Song W, Colonna M, Herms J, Wurst W, Pocock JM & Haass C
The Trem2 R47H Alzheimer's risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans.
Molecular neurodegeneration, 2018 Sep 06, 13 (1) 49

Biczok A, Kraus T, Suchorska B, Terpolilli NA, Thorsteinsdottir J, Giese A, Tonn JC & Schichor C
TERT promoter mutation is associated with worse prognosis in WHO grade II and III meningiomas.
Journal of neuro-oncology, 2018 Sep, 139 (3) 671-678

Luckner M, Burgold S, Filser S, Scheungrab M, Niyaz Y, Hummel E, Wanner G & Herms J
Label-free 3D-CLEM Using Endogenous Tissue Landmarks.
iScience, 2018 Aug 31, 6 92-101

Ronellenfitsch MW, Zeiner PS, Mittelbronn M, Urban H, Pietsch T, Reuter D, Senft C, Steinbach JP, Westphal M & Harter PN
Akt and mTORC1 signaling as predictive biomarkers for the EGFR antibody nimotuzumab in glioblastoma.
Acta neuropathologica communications, 2018 Aug 21, 6 (1) 81

Bunse L, Pusch S, Bunse T, Sahm F, Sanghvi K, Friedrich M, Alansary D, Sonner JK, Green E, Deumelandt K, Kilian M, Neftel C, Uhlig S, Kessler T, von Landenberg A, Berghoff AS, Marsh K, Steadman M, Zhu D, Nicolay B, Wiestler B, Breckwoldt MO, Al-Ali R, Karcher-Bausch S, Bozza M, Oezen I, Kramer M, Meyer J, Habel A, Eisel J, Poschet G, Weller M, Preusser M, Nadji-Ohl M, Thon N, Burger MC, Harter PN, Ratliff M, Harbottle R, Benner A, Schrimpf D, Okun J, Herold-Mende C, Turcan S, Kaulfuss S, Hess-Stumpp H, Bieback K, Cahill DP, Plate KH, Hänggi D, Dorsch M, Suvà ML, Niemeyer BA, von Deimling A, Wick W & Platten M
Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate.
Nature medicine, 2018 Aug, 24 (8) 1192-1203

Deussing M, Blume T, Vomacka L, Mahler C, Focke C, Todica A, Unterrainer M, Albert NL, Lindner S, von Ungern-Sternberg B, Baumann K, Zwergal A, Bartenstein P, Herms J, Rominger A & Brendel M
Data on specificity of [18F]GE180 uptake for TSPO expression in rodent brain and myocardium.
Data in brief, 2018 Aug, 19 331-336

Weber A, Schwarz SC, Tost J, Trümbach D, Winter P, Busato F, Tacik P, Windhorst AC, Fagny M, Arzberger T, McLean C, van Swieten JC, Schwarz J, Vogt Weisenhorn D, Wurst W, Adhikary T, Dickson DW, Höglinger GU & Müller U
Epigenome-wide DNA methylation profiling in Progressive Supranuclear Palsy reveals major changes at DLX1.
Nature communications, 2018 Jul 26, 9 (1) 2929

Gasparoni G, Bultmann S, Lutsik P, Kraus TFJ, Sordon S, Vlcek J, Dietinger V, Steinmaurer M, Haider M, Mulholland CB, Arzberger T, Roeber S, Riemenschneider M, Kretzschmar HA, Giese A, Leonhardt H & Walter J
DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
Epigenetics & chromatin, 2018 Jul 25, 11 (1) 41

Zellner A, Scharrer E, Arzberger T, Oka C, Domenga-Denier V, Joutel A, Lichtenthaler SF, Müller SA, Dichgans M & Haffner C
CADASIL brain vessels show a HTRA1 loss-of-function profile.
Acta neuropathologica, 2018 Jul, 136 (1) 111-125

Unterrainer M, Winkelmann I, Suchorska B, Giese A, Wenter V, Kreth FW, Herms J, Bartenstein P, Tonn JC & Albert NL
Biological tumour volumes of gliomas in early and standard 20-40 min 18F-FET PET images differ according to IDH mutation status.
European journal of nuclear medicine and molecular imaging, 2018 Jul, 45 (7) 1242-1249

Albani A, Pérez-Rivas LG, Dimopoulou C, Zopp S, Colón-Bolea P, Roeber S, Honegger J, Flitsch J, Rachinger W, Buchfelder M, Stalla GK, Herms J, Reincke M & Theodoropoulou M
The USP8 mutational status may predict long-term remission in patients with Cushing's disease.
Clinical endocrinology, 2018 Jun 29

Katz LM, Hielscher T, Liechty B, Silverman J, Zagzag D, Sen R, Wu P, Golfinos JG, Reuss D, Neidert MC, Wirsching HG, Baumgarten P, Herold-Mende C, Wick W, Harter PN, Weller M, von Deimling A, Snuderl M, Sen C & Sahm F
Loss of histone H3K27me3 identifies a subset of meningiomas with increased risk of recurrence.
Acta neuropathologica, 2018 Jun, 135 (6) 955-963

Schnell O, Albrecht V, Pfirrmann D, Eigenbrod S, Krebs B, Romagna A, Siller S, Giese A, Tonn JC & Schichor C
MGMT promoter methylation is not correlated with integrin expression in malignant gliomas: clarifying recent clinical trial results.
Medical oncology (Northwood, London, England), 2018 Jun 07, 35 (7) 103

Jennewein L, Bartsch G, Gust K, Kvasnicka HM, Haferkamp A, Blaheta R, Mittelbronn M, Harter PN & Mani J
Increased tumor vascularization is associated with the amount of immune competent PD-1 positive cells in testicular germ cell tumors.
Oncology letters, 2018 Jun, 15 (6) 9852-9860

Unterrainer M, Winkelmann I, Suchorska B, Giese A, Wenter V, Kreth FW, Herms J, Bartenstein P, Tonn JC & Albert NL
Correction to: Biological tumour volumes of gliomas in early and standard 20-40 min 18F-FET PET images differ according to IDH mutation status.
European journal of nuclear medicine and molecular imaging, 2018 Jun, 45 (6) 1078

Eskilsson E, Røsland GV, Solecki G, Wang Q, Harter PN, Graziani G, Verhaak RGW, Winkler F, Bjerkvig R & Miletic H
EGFR heterogeneity and implications for therapeutic intervention in glioblastoma.
Neuro-oncology, 2018 May 18, 20 (6) 743-752

Luger AL, Sauer B, Lorenz NI, Engel AL, Braun Y, Voss M, Harter PN, Steinbach JP & Ronellenfitsch MW
Doxycycline Impairs Mitochondrial Function and Protects Human Glioma Cells from Hypoxia-Induced Cell Death: Implications of Using Tet-Inducible Systems.
International journal of molecular sciences, 2018 May 17, 19 (5)

Peters F, Salihoglu H, Rodrigues E, Herzog E, Blume T, Filser S, Dorostkar M, Shimshek DR, Brose N, Neumann U & Herms J
BACE1 inhibition more effectively suppresses initiation than progression of β-amyloid pathology.
Acta neuropathologica, 2018 May, 135 (5) 695-710

Dubinski D, Won SY, Gessler F, Quick-Weller J, Behmanesh B, Bernatz S, Forster MT, Franz K, Plate KH, Seifert V, Harter PN & Senft C
Dexamethasone-induced leukocytosis is associated with poor survival in newly diagnosed glioblastoma.
Journal of neuro-oncology, 2018 May, 137 (3) 503-510

King R, Li Y, Wang J, Struebing FL & Geisert EE
Genomic Locus Modulating IOP in the BXD RI Mouse Strains.
G3 (Bethesda, Md.), 2018 May 04, 8 (5) 1571-1578

Hartmann H, Hornburg D, Czuppa M, Bader J, Michaelsen M, Farny D, Arzberger T, Mann M, Meissner F & Edbauer D
Proteomics and C9orf72 neuropathology identify ribosomes as poly-GR/PR interactors driving toxicity.
Life science alliance, 2018 May, 1 (2) e201800070

Mäder L, Blank AE, Capper D, Jansong J, Baumgarten P, Wirsik NM, Zachskorn C, Ehlers J, Seifert M, Klink B, Liebner S, Niclou S, Naumann U, Harter PN & Mittelbronn M
Pericytes/vessel-associated mural cells (VAMCs) are the major source of key epithelial-mesenchymal transition (EMT) factors SLUG and TWIST in human glioma.
Oncotarget, 2018 May 08, 9 (35) 24041-24053

Filbin MG, Tirosh I, Hovestadt V, Shaw ML, Escalante LE, Mathewson ND, Neftel C, Frank N, Pelton K, Hebert CM, Haberler C, Yizhak K, Gojo J, Egervari K, Mount C, van Galen P, Bonal DM, Nguyen QD, Beck A, Sinai C, Czech T, Dorfer C, Goumnerova L, Lavarino C, Carcaboso AM, Mora J, Mylvaganam R, Luo CC, Peyrl A, Popović M, Azizi A, Batchelor TT, Frosch MP, Martinez-Lage M, Kieran MW, Bandopadhayay P, Beroukhim R, Fritsch G, Getz G, Rozenblatt-Rosen O, Wucherpfennig KW, Louis DN, Monje M, Slavc I, Ligon KL, Golub TR, Regev A, Bernstein BE & Suvà ML
Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq.
Science (New York, N.Y.), 2018 Apr 20, 360 (6386) 331-335

Groß A, Schulz C, Kolb J, Koster J, Wehner S, Czaplinski S, Khilan A, Rohrer H, Harter PN, Klingebiel T, Langer JD, Geerts D & Schulte D
Tumorigenic and Antiproliferative Properties of the TALE-Transcription Factors MEIS2D and MEIS2A in Neuroblastoma.
Cancer research, 2018 Apr 15, 78 (8) 1935-1947

Liu J, Heinsen H, Grinberg LT, Alho E, Amaro E, Pasqualucci CA, Rüb U, den Dunnen W, Arzberger T, Schmitz C, Kiessling M, Bader B & Danek A
Subcortical neurodegeneration in chorea: Similarities and differences between chorea-acanthocytosis and Huntington's disease.
Parkinsonism & related disorders, 2018 Apr, 49 54-59

Struebing FL, King R, Li Y, Cooke Bailey JN, NEIGHBORHOOD consortium, Wiggs JL & Geisert EE
Genomic loci modulating retinal ganglion cell death following elevated IOP in the mouse.
Experimental eye research, 2018 Apr, 169 61-67

Reiner AM, Schmidt F, Ryazanov S, Leonov A, Weckbecker D, Deeg AA, Griesinger C, Giese A & Zinth W
Photophysics of diphenyl-pyrazole compounds in solutions and α-synuclein aggregates.
Biochimica et biophysica acta. General subjects, 2018 Apr, 1862 (4) 800-807

Schrötter A, Oberhaus A, Kolbe K, Seger S, Mastalski T, El Magraoui F, Hoffmann-Posorske E, Bohnert M, Deckert J, Braun C, Graw M, Schmitz C, Arzberger T, Loosse C, Heinsen H, Meyer HE & Müller T
Corrigendum to "LMD proteomics provides evidence for hippocampus field-specific motor protein abundance changes with relevance to Alzheimer's disease" [BBAPAP 1865 (6) (2017) 703-714].
Biochimica et biophysica acta. Proteins and proteomics, 2018 Apr, 1866 (4) 580

Capper D, Jones DTW, Sill M, Hovestadt V, Schrimpf D, Sturm D, Koelsche C, Sahm F, Chavez L, Reuss DE, Kratz A, Wefers AK, Huang K, Pajtler KW, Schweizer L, Stichel D, Olar A, Engel NW, Lindenberg K, Harter PN, Braczynski AK, Plate KH, Dohmen H, Garvalov BK, Coras R, Hölsken A, Hewer E, Bewerunge-Hudler M, Schick M, Fischer R, Beschorner R, Schittenhelm J, Staszewski O, Wani K, Varlet P, Pages M, Temming P, Lohmann D, Selt F, Witt H, Milde T, Witt O, Aronica E, Giangaspero F, Rushing E, Scheurlen W, Geisenberger C, Rodriguez FJ, Becker A, Preusser M, Haberler C, Bjerkvig R, Cryan J, Farrell M, Deckert M, Hench J, Frank S, Serrano J, Kannan K, Tsirigos A, Brück W, Hofer S, Brehmer S, Seiz-Rosenhagen M, Hänggi D, Hans V, Rozsnoki S, Hansford JR, Kohlhof P, Kristensen BW, Lechner M, Lopes B, Mawrin C, Ketter R, Kulozik A, Khatib Z, Heppner F, Koch A, Jouvet A, Keohane C, Mühleisen H, Mueller W, Pohl U, Prinz M, Benner A, Zapatka M, Gottardo NG, Driever PH, Kramm CM, Müller HL, Rutkowski S, von Hoff K, Frühwald MC, Gnekow A, Fleischhack G, Tippelt S, Calaminus G, Monoranu CM, Perry A, Jones C, Jacques TS, Radlwimmer B, Gessi M, Pietsch T, Schramm J, Schackert G, Westphal M, Reifenberger G, Wesseling P, Weller M, Collins VP, Blümcke I, Bendszus M, Debus J, Huang A, Jabado N, Northcott PA, Paulus W, Gajjar A, Robinson GW, Taylor MD, Jaunmuktane Z, Ryzhova M, Platten M, Unterberg A, Wick W, Karajannis MA, Mittelbronn M, Acker T, Hartmann C, Aldape K, Schüller U, Buslei R, Lichter P, Kool M, Herold-Mende C, Ellison DW, Hasselblatt M, Snuderl M, Brandner S, Korshunov A, von Deimling A & Pfister SM
DNA methylation-based classification of central nervous system tumours.
Nature, 2018 Mar 22, 555 (7697) 469-474

Arzberger T, Schludi MH, Lehmer C, Schmid B & Edbauer D
RNA versus protein toxicity in C9orf72 ALS/FTLD.
Acta neuropathologica, 2018 Mar, 135 (3) 475-479

Steinacker P, Verde F, Fang L, Feneberg E, Oeckl P, Roeber S, Anderl-Straub S, Danek A, Diehl-Schmid J, Fassbender K, Fliessbach K, Foerstl H, Giese A, Jahn H, Kassubek J, Kornhuber J, Landwehrmeyer GB, Lauer M, Pinkhardt EH, Prudlo J, Rosenbohm A, Schneider A, Schroeter ML, Tumani H, von Arnim CAF, Weishaupt J, Weydt P, Ludolph AC, Yilmazer Hanke D, Otto M & FTLDc study group
Chitotriosidase (CHIT1) is increased in microglia and macrophages in spinal cord of amyotrophic lateral sclerosis and cerebrospinal fluid levels correlate with disease severity and progression.
Journal of neurology, neurosurgery, and psychiatry, 2018 Mar, 89 (3) 239-247

Zhu K, Xiang X, Filser S, Marinković P, Dorostkar MM, Crux S, Neumann U, Shimshek DR, Rammes G, Haass C, Lichtenthaler SF, Gunnersen JM & Herms J
Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibition Impairs Synaptic Plasticity via Seizure Protein 6.
Biological psychiatry, 2018 Mar 01, 83 (5) 428-437

Zeiner PS, Zinke J, Kowalewski DJ, Bernatz S, Tichy J, Ronellenfitsch MW, Thorsen F, Berger A, Forster MT, Muller A, Steinbach JP, Beschorner R, Wischhusen J, Kvasnicka HM, Plate KH, Stefanović S, Weide B, Mittelbronn M & Harter PN
CD74 regulates complexity of tumor cell HLA class II peptidome in brain metastasis and is a positive prognostic marker for patient survival.
Acta neuropathologica communications, 2018 Mar 01, 6 (1) 18

Blasel S, Vorwerk R, Kiyose M, Mittelbronn M, Brunnberg U, Ackermann H, Voss M, Harter PN & Hattingen E
New MR perfusion features in primary central nervous system lymphomas: pattern and prognostic impact.
Journal of neurology, 2018 Mar, 265 (3) 647-658

Walter D, Harter PN, Battke F, Winkelmann R, Schneider M, Holzer K, Koch C, Bojunga J, Zeuzem S, Hansmann ML, Peveling-Oberhag J & Waidmann O
Genetic heterogeneity of primary lesion and metastasis in small intestine neuroendocrine tumors.
Scientific reports, 2018 Feb 28, 8 (1) 3811

Eriksson JA, Wanka C, Burger MC, Urban H, Hartel I, von Renesse J, Harter PN, Mittelbronn M, Steinbach JP & Rieger J
Suppression of oxidative phosphorylation confers resistance against bevacizumab in experimental glioma.
Journal of neurochemistry, 2018 Feb, 144 (4) 421-430

Suchorska B, Giese A, Biczok A, Unterrainer M, Weller M, Drexler M, Bartenstein P, Schüller U, Tonn JC & Albert NL
Identification of time-to-peak on dynamic 18F-FET-PET as a prognostic marker specifically in IDH1/2 mutant diffuse astrocytoma.
Neuro-oncology, 2018 Jan 22, 20 (2) 279-288

Deussing M, Blume T, Vomacka L, Mahler C, Focke C, Todica A, Unterrainer M, Albert NL, Lindner S, von Ungern-Sternberg B, Baumann K, Zwergal A, Bartenstein P, Herms J, Rominger A & Brendel M
Coupling between physiological TSPO expression in brain and myocardium allows stabilization of late-phase cerebral [18F]GE180 PET quantification.
NeuroImage, 2018 Jan 15, 165 83-91

Brendel M, Jaworska A, Overhoff F, Blume T, Probst F, Gildehaus FJ, Bartenstein P, Haass C, Bohrmann B, Herms J, Willem M & Rominger A
Efficacy of chronic BACE1 inhibition in PS2APP mice depends on the regional Aβ deposition rate and plaque burden at treatment initiation.
Theranostics, 2018, 8 (18) 4957-4968

Struebing FL, King R, Li Y, Chrenek MA, Lyuboslavsky PN, Sidhu CS, Iuvone PM & Geisert EE
Transcriptional Changes in the Mouse Retina after Ocular Blast Injury: A Role for the Immune System.
Journal of neurotrauma, 2018 Jan 01, 35 (1) 118-129

Wang J, Struebing FL, Ferdous S, Donaldson K, Boatright JH, Geisert EE & Nickerson JM
Differential Exon Expression in a Large Family of Retinal Genes Is Regulated by a Single Trans Locus.
Advances in experimental medicine and biology, 2018, 1074 413-420

Beck A, Trippel F, Wagner A, Joppien S, Felle M, Vokuhl C, Schwarzmayr T, Strom TM, von Schweinitz D, Längst G & Kappler R
Overexpression of UHRF1 promotes silencing of tumor suppressor genes and predicts outcome in hepatoblastoma.
Clinical epigenetics, 2018, 10 27

Martinez Hernandez A, Urbanke H, Gillman AL, Lee J, Ryazanov S, Agbemenyah HY, Benito E, Jain G, Kaurani L, Grigorian G, Leonov A, Rezaei-Ghaleh N, Wilken P, Arce FT, Wagner J, Fuhrmann M, Caruana M, Camilleri A, Vassallo N, Zweckstetter M, Benz R, Giese A, Schneider A, Korte M, Lal R, Griesinger C, Eichele G & Fischer A
The diphenylpyrazole compound anle138b blocks Aβ channels and rescues disease phenotypes in a mouse model for amyloid pathology.
EMBO molecular medicine, 2018 Jan, 10 (1) 32-47

Wang J, Li Y, King R, Struebing FL & Geisert EE
Optic nerve regeneration in the mouse is a complex trait modulated by genetic background.
Molecular vision, 2018, 24 174-186

Ronellenfitsch MW, Oh JE, Satomi K, Sumi K, Harter PN, Steinbach JP, Felsberg J, Capper D, Voegele C, Durand G, McKay J, Le Calvez-Kelm F, Schittenhelm J, Klink B, Mittelbronn M & Ohgaki H
CASP9 germline mutation in a family with multiple brain tumors.
Brain pathology (Zurich, Switzerland), 2018 Jan, 28 (1) 94-102

Quick-Weller J, Tichy J, Harter PN, Tritt S, Baumgarten P, Bähr O, Dinc N, Behmanesh B, Weise L, Seifert V & Marquardt G
"Two is not enough" - Impact of the number of tissue samples obtained from stereotactic brain biopsies in suspected glioblastoma.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2018 Jan, 47 311-314

King R, Struebing FL, Li Y, Wang J, Koch AA, Cooke Bailey JN, Gharahkhani P, International Glaucoma Genetics Consortium, NEIGHBORHOOD Consortium, MacGregor S, Allingham RR, Hauser MA, Wiggs JL & Geisert EE
Genomic locus modulating corneal thickness in the mouse identifies POU6F2 as a potential risk of developing glaucoma.
PLoS genetics, 2018 Jan, 14 (1) e1007145

Li Y, Struebing FL, Wang J, King R & Geisert EE
Different Effect of Sox11 in Retinal Ganglion Cells Survival and Axon Regeneration.
Frontiers in genetics, 2018, 9 633

Blume T, Filser S, Jaworska A, Blain JF, Koenig G, Moschke K, Lichtenthaler SF & Herms J
BACE1 Inhibitor MK-8931 Alters Formation but Not Stability of Dendritic Spines.
Frontiers in aging neuroscience, 2018, 10 229

Brendel M, Yousefi BH, Blume T, Herz M, Focke C, Deussing M, Peters F, Lindner S, von Ungern-Sternberg B, Drzezga A, Bartenstein P, Haass C, Okamura N, Herms J, Yakushev I & Rominger A
Comparison of 18F-T807 and 18F-THK5117 PET in a Mouse Model of Tau Pathology.
Frontiers in aging neuroscience, 2018, 10 174

Schönecker S, Neuhofer C, Otto M, Ludolph A, Kassubek J, Landwehrmeyer B, Anderl-Straub S, Semler E, Diehl-Schmid J, Prix C, Vollmar C, Fortea J, Deutsches FTLD-Konsortium, Huppertz HJ, Arzberger T, Edbauer D, Feddersen B, Dieterich M, Schroeter ML, Volk AE, Fließbach K, Schneider A, Kornhuber J, Maler M, Prudlo J, Jahn H, Boeckh-Behrens T, Danek A, Klopstock T & Levin J
Atrophy in the Thalamus But Not Cerebellum Is Specific for C9orf72 FTD and ALS Patients - An Atlas-Based Volumetric MRI Study.
Frontiers in aging neuroscience, 2018, 10 45

2017

Burger MC, Ronellenfitsch MW, Lorenz NI, Wagner M, Voss M, Capper D, Tzaridis T, Herrlinger U, Steinbach JP, Stoffels G, Langen KJ, Brandts C, Senft C, Harter PN & Bähr O
Dabrafenib in patients with recurrent, BRAF V600E mutated malignant glioma and leptomeningeal disease.
Oncology reports, 2017 Dec, 38 (6) 3291-3296

Llovera G, Benakis C, Enzmann G, Cai R, Arzberger T, Ghasemigharagoz A, Mao X, Malik R, Lazarevic I, Liebscher S, Ertürk A, Meissner L, Vivien D, Haffner C, Plesnila N, Montaner J, Engelhardt B & Liesz A
The choroid plexus is a key cerebral invasion route for T cells after stroke.
Acta neuropathologica, 2017 Dec, 134 (6) 851-868

Brendel M, Focke C, Blume T, Peters F, Deussing M, Probst F, Jaworska A, Overhoff F, Albert N, Lindner S, von Ungern-Sternberg B, Bartenstein P, Haass C, Kleinberger G, Herms J & Rominger A
Time Courses of Cortical Glucose Metabolism and Microglial Activity Across the Life Span of Wild-Type Mice: A PET Study.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2017 Dec, 58 (12) 1984-1990

Burger MC, Breuer S, Cieplik HC, Harter PN, Franz K, Bähr O & Steinbach JP
Bevacizumab for Patients with Recurrent Multifocal Glioblastomas.
International journal of molecular sciences, 2017 Nov 20, 18 (11)

Papasavva-Stylianou P, Simmons MM, Ortiz-Pelaez A, Windl O, Spiropoulos J & Georgiadou S
Effect of Polymorphisms at Codon 146 of the Goat PRNP Gene on Susceptibility to Challenge with Classical Scrapie by Different Routes.
Journal of virology, 2017 Nov 15, 91 (22)

Bähr O, Gross S, Harter PN, Kirches E, Mawrin C, Steinbach JP & Mittelbronn M
ASA404, a vascular disrupting agent, as an experimental treatment approach for brain tumors.
Oncology letters, 2017 Nov, 14 (5) 5443-5451

Ovsepian SV, Blazquez-Llorca L, Freitag SV, Rodrigues EF & Herms J
Ambient Glutamate Promotes Paroxysmal Hyperactivity in Cortical Pyramidal Neurons at Amyloid Plaques via Presynaptic mGluR1 Receptors.
Cerebral cortex (New York, N.Y. : 1991), 2017 Oct 01, 27 (10) 4733-4749

Neumann JE, Wefers AK, Lambo S, Bianchi E, Bockstaller M, Dorostkar MM, Meister V, Schindler P, Korshunov A, von Hoff K, Nowak J, Warmuth-Metz M, Schneider MR, Renner-Müller I, Merk DJ, Shakarami M, Sharma T, Chavez L, Glass R, Chan JA, Taketo MM, Neumann P, Kool M & Schüller U
A mouse model for embryonal tumors with multilayered rosettes uncovers the therapeutic potential of Sonic-hedgehog inhibitors.
Nature medicine, 2017 Oct, 23 (10) 1191-1202

Thiepold AL, Lorenz NI, Foltyn M, Engel AL, Divé I, Urban H, Heller S, Bruns I, Hofmann U, Dröse S, Harter PN, Mittelbronn M, Steinbach JP & Ronellenfitsch MW
Mammalian target of rapamycin complex 1 activation sensitizes human glioma cells to hypoxia-induced cell death.
Brain : a journal of neurology, 2017 Oct 01, 140 (10) 2623-2638

Ilina EI, Armento A, Sanchez LG, Reichlmeir M, Braun Y, Penski C, Capper D, Sahm F, Jennewein L, Harter PN, Zukunft S, Fleming I, Schulte D, Le Guerroué F, Behrends C, Ronellenfitsch MW, Naumann U & Mittelbronn M
Effects of soluble CPE on glioma cell migration are associated with mTOR activation and enhanced glucose flux.
Oncotarget, 2017 Sep 15, 8 (40) 67567-67591

Vettermann FJ, Neumann JE, Suchorska B, Bartenstein P, Giese A, Dorostkar MM, Albert NL & Schüller U
K27M midline gliomas display malignant progression by imaging and histology.
Neuropathology and applied neurobiology, 2017 Aug, 43 (5) 458-462

Schludi MH, Becker L, Garrett L, Gendron TF, Zhou Q, Schreiber F, Popper B, Dimou L, Strom TM, Winkelmann J, von Thaden A, Rentzsch K, May S, Michaelsen M, Schwenk BM, Tan J, Schoser B, Dieterich M, Petrucelli L, Hölter SM, Wurst W, Fuchs H, Gailus-Durner V, de Angelis MH, Klopstock T, Arzberger T & Edbauer D
Spinal poly-GA inclusions in a C9orf72 mouse model trigger motor deficits and inflammation without neuron loss.
Acta neuropathologica, 2017 Aug, 134 (2) 241-254

Torres-Odio S, Key J, Hoepken HH, Canet-Pons J, Valek L, Roller B, Walter M, Morales-Gordo B, Meierhofer D, Harter PN, Mittelbronn M, Tegeder I, Gispert S & Auburger G
Progression of pathology in PINK1-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation.
Journal of neuroinflammation, 2017 Aug 02, 14 (1) 154

Ahlfeld J, Filser S, Schmidt F, Wefers AK, Merk DJ, Glaß R, Herms J & Schüller U
Neurogenesis from Sox2 expressing cells in the adult cerebellar cortex.
Scientific reports, 2017 Jul 21, 7 (1) 6137

Sgobio C, Wu J, Zheng W, Chen X, Pan J, Salinas AG, Davis MI, Lovinger DM & Cai H
Aldehyde dehydrogenase 1-positive nigrostriatal dopaminergic fibers exhibit distinct projection pattern and dopamine release dynamics at mouse dorsal striatum.
Scientific reports, 2017 Jul 13, 7 (1) 5283

Harter PN, Braun Y & Plate KH
Classification of meningiomas-advances and controversies.
Chinese clinical oncology, 2017 Jul, 6 (Suppl 1) S2

Respondek G, Kurz C, Arzberger T, Compta Y, Englund E, Ferguson LW, Gelpi E, Giese A, Irwin DJ, Meissner WG, Nilsson C, Pantelyat A, Rajput A, van Swieten JC, Troakes C, Josephs KA, Lang AE, Mollenhauer B, Müller U, Whitwell JL, Antonini A, Bhatia KP, Bordelon Y, Corvol JC, Colosimo C, Dodel R, Grossman M, Kassubek J, Krismer F, Levin J, Lorenzl S, Morris H, Nestor P, Oertel WH, Rabinovici GD, Rowe JB, van Eimeren T, Wenning GK, Boxer A, Golbe LI, Litvan I, Stamelou M, Höglinger GU & Movement Disorder Society-Endorsed PSP Study Group
Which ante mortem clinical features predict progressive supranuclear palsy pathology?
Movement disorders : official journal of the Movement Disorder Society, 2017 Jul, 32 (7) 995-1005

Lehmer C, Oeckl P, Weishaupt JH, Volk AE, Diehl-Schmid J, Schroeter ML, Lauer M, Kornhuber J, Levin J, Fassbender K, Landwehrmeyer B, German Consortium for Frontotemporal Lobar Degeneration, Schludi MH, Arzberger T, Kremmer E, Flatley A, Feederle R, Steinacker P, Weydt P, Ludolph AC, Edbauer D & Otto M
Poly-GP in cerebrospinal fluid links C9orf72-associated dipeptide repeat expression to the asymptomatic phase of ALS/FTD.
EMBO molecular medicine, 2017 Jul, 9 (7) 859-868

Gfroerer S, Theilen TM, Fiegel H, Harter PN, Mittelbronn M & Rolle U
Identification of intestinal ganglioneuromatosis leads to early diagnosis of MEN2B: role of rectal biopsy.
Journal of pediatric surgery, 2017 Jul, 52 (7) 1161-1165

Kleinberger G, Brendel M, Mracsko E, Wefers B, Groeneweg L, Xiang X, Focke C, Deußing M, Suárez-Calvet M, Mazaheri F, Parhizkar S, Pettkus N, Wurst W, Feederle R, Bartenstein P, Mueggler T, Arzberger T, Knuesel I, Rominger A & Haass C
The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism.
The EMBO journal, 2017 Jul 03, 36 (13) 1837-1853

Matz G, Messerschmidt B, Göbel W, Filser S, Betz CS, Kirsch M, Uckermann O, Kunze M, Flämig S, Ehrhardt A, Irion KM, Haack M, Dorostkar MM, Herms J & Gross H
Chip-on-the-tip compact flexible endoscopic epifluorescence video-microscope for in-vivo imaging in medicine and biomedical research.
Biomedical optics express, 2017 Jul 01, 8 (7) 3329-3342

Wenger KJ, Wagner M, You SJ, Franz K, Harter PN, Burger MC, Voss M, Ronellenfitsch MW, Fokas E, Steinbach JP & Bähr O
Bevacizumab as a last-line treatment for glioblastoma following failure of radiotherapy, temozolomide and lomustine.
Oncology letters, 2017 Jul, 14 (1) 1141-1146

Bicker F, Vasic V, Horta G, Ortega F, Nolte H, Kavyanifar A, Keller S, Stankovic ND, Harter PN, Benedito R, Lutz B, Bäuerle T, Hartwig J, Baumgart J, Krüger M, Radyushkin K, Alberi L, Berninger B & Schmidt MHH
Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception.
Nature communications, 2017 Jun 28, 8 15922

Turriani E, Lázaro DF, Ryazanov S, Leonov A, Giese A, Schön M, Schön MP, Griesinger C, Outeiro TF, Arndt-Jovin DJ & Becker D
Treatment with diphenyl-pyrazole compound anle138b/c reveals that α-synuclein protects melanoma cells from autophagic cell death.
Proceedings of the National Academy of Sciences of the United States of America, 2017 Jun 20, 114 (25) E4971-E4977

Herms J & Schön C
In vivo imaging of retinal neurodegeneration at the single cell level in humans.
Brain : a journal of neurology, 2017 Jun 01, 140 (6) 1542-1543

Gessler F, Baumgarten P, Bernstock JD, Harter P, Lescher S, Senft C, Seifert V, Marquardt G & Weise L
Assessment of molecular markers demonstrates concordance between samples acquired via stereotactic biopsy and open craniotomy in both anaplastic astrocytomas and glioblastomas.
Journal of neuro-oncology, 2017 Jun, 133 (2) 399-407

Höglinger GU, Respondek G, Stamelou M, Kurz C, Josephs KA, Lang AE, Mollenhauer B, Müller U, Nilsson C, Whitwell JL, Arzberger T, Englund E, Gelpi E, Giese A, Irwin DJ, Meissner WG, Pantelyat A, Rajput A, van Swieten JC, Troakes C, Antonini A, Bhatia KP, Bordelon Y, Compta Y, Corvol JC, Colosimo C, Dickson DW, Dodel R, Ferguson L, Grossman M, Kassubek J, Krismer F, Levin J, Lorenzl S, Morris HR, Nestor P, Oertel WH, Poewe W, Rabinovici G, Rowe JB, Schellenberg GD, Seppi K, van Eimeren T, Wenning GK, Boxer AL, Golbe LI, Litvan I & Movement Disorder Society-endorsed PSP Study Group
Clinical diagnosis of progressive supranuclear palsy: The movement disorder society criteria.
Movement disorders : official journal of the Movement Disorder Society, 2017 Jun, 32 (6) 853-864

Schrötter A, Oberhaus A, Kolbe K, Seger S, Mastalski T, El Magraoui F, Hoffmann-Posorske E, Bohnert M, Deckert J, Braun C, Graw M, Schmitz C, Arzberger T, Loosse C, Heinsen H, Meyer HE & Müller T
LMD proteomics provides evidence for hippocampus field-specific motor protein abundance changes with relevance to Alzheimer's disease.
Biochimica et biophysica acta. Proteins and proteomics, 2017 Jun, 1865 (6) 703-714

Blumenstock S, Rodrigues EF, Peters F, Blazquez-Llorca L, Schmidt F, Giese A & Herms J
Seeding and transgenic overexpression of alpha-synuclein triggers dendritic spine pathology in the neocortex.
EMBO molecular medicine, 2017 May, 9 (5) 716-731

Zhou Q, Lehmer C, Michaelsen M, Mori K, Alterauge D, Baumjohann D, Schludi MH, Greiling J, Farny D, Flatley A, Feederle R, May S, Schreiber F, Arzberger T, Kuhm C, Klopstock T, Hermann A, Haass C & Edbauer D
Antibodies inhibit transmission and aggregation of C9orf72 poly-GA dipeptide repeat proteins.
EMBO molecular medicine, 2017 May, 9 (5) 687-702

Dietrich O, Levin J, Ahmadi SA, Plate A, Reiser MF, Bötzel K, Giese A & Ertl-Wagner B
MR imaging differentiation of Fe2+ and Fe3+ based on relaxation and magnetic susceptibility properties.
Neuroradiology, 2017 Apr, 59 (4) 403-409

Hagel C, Buslei R, Buchfelder M, Fahlbusch R, Bergmann M, Giese A, Flitsch J, Lüdecke DK, Glatzel M & Saeger W
Immunoprofiling of glial tumours of the neurohypophysis suggests a common pituicytic origin of neoplastic cells.
Pituitary, 2017 Apr, 20 (2) 211-217

Dunn AR, Stout KA, Ozawa M, Lohr KM, Hoffman CA, Bernstein AI, Li Y, Wang M, Sgobio C, Sastry N, Cai H, Caudle WM & Miller GW
Synaptic vesicle glycoprotein 2C (SV2C) modulates dopamine release and is disrupted in Parkinson disease.
Proceedings of the National Academy of Sciences of the United States of America, 2017 Mar 14, 114 (11) E2253-E2262

Bruch J, Xu H, Rösler TW, De Andrade A, Kuhn PH, Lichtenthaler SF, Arzberger T, Winklhofer KF, Müller U & Höglinger GU
PERK activation mitigates tau pathology in vitro and in vivo.
EMBO molecular medicine, 2017 Mar, 9 (3) 371-384

Talasila KM, Røsland GV, Hagland HR, Eskilsson E, Flønes IH, Fritah S, Azuaje F, Atai N, Harter PN, Mittelbronn M, Andersen M, Joseph JV, Hossain JA, Vallar L, Noorden CJ, Niclou SP, Thorsen F, Tronstad KJ, Tzoulis C, Bjerkvig R & Miletic H
The angiogenic switch leads to a metabolic shift in human glioblastoma.
Neuro-oncology, 2017 Mar 01, 19 (3) 383-393

Blazquez-Llorca L, Valero-Freitag S, Rodrigues EF, Merchán-Pérez Á, Rodríguez JR, Dorostkar MM, DeFelipe J & Herms J
High plasticity of axonal pathology in Alzheimer's disease mouse models.
Acta neuropathologica communications, 2017 Feb 07, 5 (1) 14

Behmanesh B, Setzer M, Konczalla J, Harter P, Quick-Weller J, Imoehl L, Franz K, Gessler F, Seifert V & Marquardt G
Management of Patients with Primary Intramedullary Spinal Cord Glioblastoma.
World neurosurgery, 2017 Feb, 98 198-202

Bürger K, Arzberger T, Stephan J, Levin J & Edbauer D
[Pathomechanisms and clinical aspects of frontotemporal lobar degeneration].
Der Nervenarzt, 2017 Feb, 88 (2) 163-172

Saal KA, Galter D, Roeber S, Bähr M, Tönges L & Lingor P
Altered Expression of Growth Associated Protein-43 and Rho Kinase in Human Patients with Parkinson's Disease.
Brain pathology (Zurich, Switzerland), 2017 Jan, 27 (1) 13-25

Schön C & Herms J
In Vivo Imaging of Tau Aggregates in the Mouse Retina.
Methods in molecular biology (Clifton, N.J.), 2017, 1523 361-368

Eigenbrod S, Frick P, Bertsch U, Mitteregger-Kretzschmar G, Mielke J, Maringer M, Piening N, Hepp A, Daude N, Windl O, Levin J, Giese A, Sakthivelu V, Tatzelt J, Kretzschmar H & Westaway D
Substitutions of PrP N-terminal histidine residues modulate scrapie disease pathogenesis and incubation time in transgenic mice.
PloS one, 2017, 12 (12) e0188989

Sashourpour M, Zahri S, Radjabian T, Ruf V, Pan-Montojo F & Morshedi D
A study on the modulation of alpha-synuclein fibrillation by Scutellaria pinnatifida extracts and its neuroprotective properties.
PloS one, 2017, 12 (9) e0184483

Georgiadou S, Ortiz-Pelaez A, Simmons MM, Windl O, Dawson M, Neocleous P & Papasavva-Stylianou P
Goats with aspartic acid or serine at codon 146 of the PRNP gene remain scrapie-negative after lifetime exposure in affected herds in Cyprus.
Epidemiology and infection, 2017 Jan, 145 (2) 326-328

Struebing FL, Wang J, Li Y, King R, Mistretta OC, English AW & Geisert EE
Differential Expression of Sox11 and Bdnf mRNA Isoforms in the Injured and Regenerating Nervous Systems.
Frontiers in molecular neuroscience, 2017, 10 354

Kattah JC, Saber Tehrani AS, Roeber S, Gujrati M, Bach SE, Newman Toker DE, Blitz AM & Horn AKE
Transient Vestibulopathy in Wallenberg's Syndrome: Pathologic Analysis.
Frontiers in neurology, 2017, 8 191

Montagna E, Dorostkar MM & Herms J
The Role of APP in Structural Spine Plasticity.
Frontiers in molecular neuroscience, 2017, 10 136

Brendel M, Kleinberger G, Probst F, Jaworska A, Overhoff F, Blume T, Albert NL, Carlsen J, Lindner S, Gildehaus FJ, Ozmen L, Suárez-Calvet M, Bartenstein P, Baumann K, Ewers M, Herms J, Haass C & Rominger A
Increase of TREM2 during Aging of an Alzheimer's Disease Mouse Model Is Paralleled by Microglial Activation and Amyloidosis.
Frontiers in aging neuroscience, 2017, 9 8

2016

Steinacker P, Blennow K, Halbgebauer S, Shi S, Ruf V, Oeckl P, Giese A, Kuhle J, Slivarichova D, Zetterberg H & Otto M
Neurofilaments in blood and CSF for diagnosis and prediction of onset in Creutzfeldt-Jakob disease.
Scientific reports, 2016 Dec 08, 6 38737

Tatura R, Kraus T, Giese A, Arzberger T, Buchholz M, Höglinger G & Müller U
Parkinson's disease: SNCA-, PARK2-, and LRRK2- targeting microRNAs elevated in cingulate gyrus.
Parkinsonism & related disorders, 2016 Dec, 33 115-121

Schnell O, Thorsteinsdottir J, Fleischmann DF, Lenski M, Abenhardt W, Giese A, Tonn JC, Belka C, Kreth FW & Niyazi M
Re-irradiation strategies in combination with bevacizumab for recurrent malignant glioma.
Journal of neuro-oncology, 2016 Dec, 130 (3) 591-599

Herring A, Münster Y, Akkaya T, Moghaddam S, Deinsberger K, Meyer J, Zahel J, Sanchez-Mendoza E, Wang Y, Hermann DM, Arzberger T, Teuber-Hanselmann S & Keyvani K
Kallikrein-8 inhibition attenuates Alzheimer's disease pathology in mice.
Alzheimer's & dementia : the journal of the Alzheimer's Association, 2016 Dec, 12 (12) 1273-1287

Weide B, Schäfer T, Martens A, Kuzkina A, Uder L, Noor S, Garbe C, Harter PN, Mittelbronn M & Wischhusen J
High GDF-15 Serum Levels Independently Correlate with Poorer Overall Survival of Patients with Tumor-Free Stage III and Unresectable Stage IV Melanoma.
The Journal of investigative dermatology, 2016 Dec, 136 (12) 2444-2452

Eskilsson E, Rosland GV, Talasila KM, Knappskog S, Keunen O, Sottoriva A, Foerster S, Solecki G, Taxt T, Jirik R, Fritah S, Harter PN, Välk K, Al Hossain J, Joseph JV, Jahedi R, Saed HS, Piccirillo SG, Spiteri I, Leiss L, Euskirchen P, Graziani G, Daubon T, Lund-Johansen M, Enger PØ, Winkler F, Ritter CA, Niclou SP, Watts C, Bjerkvig R & Miletic H
EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation.
Neuro-oncology, 2016 Dec, 18 (12) 1644-1655

Müller SH, Girard SL, Hopfner F, Merner ND, Bourassa CV, Lorenz D, Clark LN, Tittmann L, Soto-Ortolaza AI, Klebe S, Hallett M, Schneider SA, Hodgkinson CA, Lieb W, Wszolek ZK, Pendziwiat M, Lorenzo-Betancor O, Poewe W, Ortega-Cubero S, Seppi K, Rajput A, Hussl A, Rajput AH, Berg D, Dion PA, Wurster I, Shulman JM, Srulijes K, Haubenberger D, Pastor P, Vilariño-Güell C, Postuma RB, Bernard G, Ladwig KH, Dupré N, Jankovic J, Strauch K, Panisset M, Winkelmann J, Testa CM, Reischl E, Zeuner KE, Ross OA, Arzberger T, Chouinard S, Deuschl G, Louis ED, Kuhlenbäumer G & Rouleau GA
Genome-wide association study in essential tremor identifies three new loci.
Brain : a journal of neurology, 2016 Dec, 139 (Pt 12) 3163-3169

Brucker DP, Maurer GD, Harter PN, Rieger J & Steinbach JP
FOXO3a orchestrates glioma cell responses to starvation conditions and promotes hypoxia-induced cell death.
International journal of oncology, 2016 Dec, 49 (6) 2399-2410

Kurz C, Ebersbach G, Respondek G, Giese A, Arzberger T & Höglinger GU
An autopsy-confirmed case of progressive supranuclear palsy with predominant postural instability.
Acta neuropathologica communications, 2016 Nov 14, 4 (1) 120

Beck A, Eberherr C, Hagemann M, Cairo S, Häberle B, Vokuhl C, von Schweinitz D & Kappler R
Connectivity map identifies HDAC inhibition as a treatment option of high-risk hepatoblastoma.
Cancer biology & therapy, 2016 Nov, 17 (11) 1168-1176

Schwenk BM, Hartmann H, Serdaroglu A, Schludi MH, Hornburg D, Meissner F, Orozco D, Colombo A, Tahirovic S, Michaelsen M, Schreiber F, Haupt S, Peitz M, Brüstle O, Küpper C, Klopstock T, Otto M, Ludolph AC, Arzberger T, Kuhn PH & Edbauer D
TDP-43 loss of function inhibits endosomal trafficking and alters trophic signaling in neurons.
The EMBO journal, 2016 Nov 02, 35 (21) 2350-2370

Romagna A, Schwartz C, Egensperger R, Watson J, Tonn JC, Belka C, Kreth FW & Nachbichler SB
Iodine-125 brachytherapy as upfront and salvage treatment for brain metastases : A comparative analysis.
Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2016 Nov, 192 (11) 780-788

Levin J, Maaß S, Schuberth M, Respondek G, Paul F, Mansmann U, Oertel WH, Lorenzl S, Krismer F, Seppi K, Poewe W, Wenning G, Berg D, Claßen J, Ebersbach G, Eggert K, Kassubek J, Lipp A, Löhle M, Mollenhauer B, Münchau A, Südmeyer M, Blankenstein C, Eberhardt C, Ertl-Wagner B, Heise H, Ricard I, PROMESA study group, Giese A, Bötzel K & Höglinger G
Erratum to: The PROMESA-protocol: progression rate of multiple system atrophy under EGCG supplementation as anti-aggregation-approach.
Journal of neural transmission (Vienna, Austria : 1996), 2016 Nov, 123 (11) 1357-1358

Zou C, Crux S, Marinesco S, Montagna E, Sgobio C, Shi Y, Shi S, Zhu K, Dorostkar MM, Müller UC & Herms J
Amyloid precursor protein maintains constitutive and adaptive plasticity of dendritic spines in adult brain by regulating D-serine homeostasis.
The EMBO journal, 2016 Oct 17, 35 (20) 2213-2222

Baumgarten P, Gessler F, Schittenhelm J, Skardelly M, Tews DS, Senft C, Dunst M, Imoehl L, Plate KH, Wagner M, Steinbach JP, Seifert V, Mittelbronn M & Harter PN
Brain invasion in otherwise benign meningiomas does not predict tumor recurrence.
Acta neuropathologica, 2016 Sep, 132 (3) 479-81

Mori K, Nihei Y, Arzberger T, Zhou Q, Mackenzie IR, Hermann A, Hanisch F, German Consortium for Frontotemporal Lobar Degeneration, Bavarian Brain Banking Alliance, Kamp F, Nuscher B, Orozco D, Edbauer D & Haass C
Reduced hnRNPA3 increases C9orf72 repeat RNA levels and dipeptide-repeat protein deposition.
EMBO reports, 2016 Sep, 17 (9) 1314-25

Levin J, Hillmer AS, Högen T, McLean PJ & Giese A
Intracellular formation of α-synuclein oligomers and the effect of heat shock protein 70 characterized by confocal single particle spectroscopy.
Biochemical and biophysical research communications, 2016 Aug 12, 477 (1) 76-82

Cescatti M, Saverioni D, Capellari S, Tagliavini F, Kitamoto T, Ironside J, Giese A & Parchi P
Analysis of Conformational Stability of Abnormal Prion Protein Aggregates across the Spectrum of Creutzfeldt-Jakob Disease Prions.
Journal of virology, 2016 Jul 15, 90 (14) 6244-6254

Devraj K, Poznanovic S, Spahn C, Schwall G, Harter PN, Mittelbronn M, Antoniello K, Paganetti P, Muhs A, Heilemann M, Hawkins RA, Schrattenholz A & Liebner S
BACE-1 is expressed in the blood-brain barrier endothelium and is upregulated in a murine model of Alzheimer's disease.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2016 Jul, 36 (7) 1281-94

Brendel M, Probst F, Jaworska A, Overhoff F, Korzhova V, Albert NL, Beck R, Lindner S, Gildehaus FJ, Baumann K, Bartenstein P, Kleinberger G, Haass C, Herms J & Rominger A
Glial Activation and Glucose Metabolism in a Transgenic Amyloid Mouse Model: A Triple-Tracer PET Study.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2016 Jun, 57 (6) 954-60

Bougnaud S, Golebiewska A, Oudin A, Keunen O, Harter PN, Mäder L, Azuaje F, Fritah S, Stieber D, Kaoma T, Vallar L, Brons NH, Daubon T, Miletic H, Sundstrøm T, Herold-Mende C, Mittelbronn M, Bjerkvig R & Niclou SP
Molecular crosstalk between tumour and brain parenchyma instructs histopathological features in glioblastoma.
Oncotarget, 2016 May 31, 7 (22) 31955-71

Herms J & Dorostkar MM
Dendritic Spine Pathology in Neurodegenerative Diseases.
Annual review of pathology, 2016 May 23, 11 221-50

Kretner B, Trambauer J, Fukumori A, Mielke J, Kuhn PH, Kremmer E, Giese A, Lichtenthaler SF, Haass C, Arzberger T & Steiner H
Generation and deposition of Aβ43 by the virtually inactive presenilin-1 L435F mutant contradicts the presenilin loss-of-function hypothesis of Alzheimer's disease.
EMBO molecular medicine, 2016 May, 8 (5) 458-65

Brendel M, Jaworska A, Probst F, Overhoff F, Korzhova V, Lindner S, Carlsen J, Bartenstein P, Harada R, Kudo Y, Haass C, Van Leuven F, Okamura N, Herms J & Rominger A
Small-Animal PET Imaging of Tau Pathology with 18F-THK5117 in 2 Transgenic Mouse Models.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2016 May, 57 (5) 792-8

Neumann JE, Dorostkar MM, Korshunov A, Mawrin C, Koch A, Giese A & Schüller U
Distinct Histomorphology in Molecular Subgroups of Glioblastomas in Young Patients.
Journal of neuropathology and experimental neurology, 2016 May, 75 (5) 408-14

Zhang C, Burger MC, Jennewein L, Genßler S, Schönfeld K, Zeiner P, Hattingen E, Harter PN, Mittelbronn M, Tonn T, Steinbach JP & Wels WS
ErbB2/HER2-Specific NK Cells for Targeted Therapy of Glioblastoma.
Journal of the National Cancer Institute, 2016 May, 108 (5)

Winter L, Türk M, Harter PN, Mittelbronn M, Kornblum C, Norwood F, Jungbluth H, Thiel CT, Schlötzer-Schrehardt U & Schröder R
Downstream effects of plectin mutations in epidermolysis bullosa simplex with muscular dystrophy.
Acta neuropathologica communications, 2016 Apr 27, 4 (1) 44

Xu J, Wu XS, Sheng J, Zhang Z, Yue HY, Sun L, Sgobio C, Lin X, Peng S, Jin Y, Gan L, Cai H & Wu LG
α-Synuclein Mutation Inhibits Endocytosis at Mammalian Central Nerve Terminals.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016 Apr 20, 36 (16) 4408-14

Jennewein L, Ronellenfitsch MW, Antonietti P, Ilina EI, Jung J, Stadel D, Flohr LM, Zinke J, von Renesse J, Drott U, Baumgarten P, Braczynski AK, Penski C, Burger MC, Theurillat JP, Steinbach JP, Plate KH, Dikic I, Fulda S, Brandts C, Kögel D, Behrends C, Harter PN & Mittelbronn M
Diagnostic and clinical relevance of the autophago-lysosomal network in human gliomas.
Oncotarget, 2016 Apr 12, 7 (15) 20016-32

Füllhase C, Schreiber A, Giese A, Schmidt M, Montorsi F, Gratzke C, La Croce G, Castiglione F, Stief C & Hedlund P
Spinal neuronal cannabinoid receptors mediate urodynamic effects of systemic fatty acid amide hydrolase (FAAH) inhibition in rats.
Neurourology and urodynamics, 2016 Apr, 35 (4) 464-70

Levin J, Maaß S, Schuberth M, Respondek G, Paul F, Mansmann U, Oertel WH, Lorenzl S, Krismer F, Seppi K, Poewe W, Wenning G, PROMESA study group, Giese A, Bötzel K & Höglinger G
The PROMESA-protocol: progression rate of multiple system atrophy under EGCG supplementation as anti-aggregation-approach.
Journal of neural transmission (Vienna, Austria : 1996), 2016 Apr, 123 (4) 439-45

Suárez-Calvet M, Neumann M, Arzberger T, Abou-Ajram C, Funk E, Hartmann H, Edbauer D, Kremmer E, Göbl C, Resch M, Bourgeois B, Madl T, Reber S, Jutzi D, Ruepp MD, Mackenzie IR, Ansorge O, Dormann D & Haass C
Monomethylated and unmethylated FUS exhibit increased binding to Transportin and distinguish FTLD-FUS from ALS-FUS.
Acta neuropathologica, 2016 Apr, 131 (4) 587-604

Schön C, Asteriti S, Koch S, Sothilingam V, Garcia Garrido M, Tanimoto N, Herms J, Seeliger MW, Cangiano L, Biel M & Michalakis S
Loss of HCN1 enhances disease progression in mouse models of CNG channel-linked retinitis pigmentosa and achromatopsia.
Human molecular genetics, 2016 Mar 15, 25 (6) 1165-75

Kunz M, Nachbichler SB, Ertl L, Fesl G, Egensperger R, Niyazi M, Schmid I, Tonn JC, Peraud A & Kreth FW
Early treatment of complex located pediatric low-grade gliomas using iodine-125 brachytherapy alone or in combination with microsurgery.
Cancer medicine, 2016 Mar, 5 (3) 442-53

Bartsch G, Jennewein L, Harter PN, Antonietti P, Blaheta RA, Kvasnicka HM, Kögel D, Haferkamp A, Mittelbronn M & Mani J
Autophagy-associated proteins BAG3 and p62 in testicular cancer.
Oncology reports, 2016 Mar, 35 (3) 1629-35

Goldmann W, Marier E, Stewart P, Konold T, Street S, Langeveld J, Windl O & Ortiz-Pelaez A
Prion protein genotype survey confirms low frequency of scrapie-resistant K222 allele in British goat herds.
The Veterinary record, 2016 Feb 13, 178 (7) 168

Levin J, Kurz A, Arzberger T, Giese A & Höglinger GU
The Differential Diagnosis and Treatment of Atypical Parkinsonism.
Deutsches Arzteblatt international, 2016 Feb 05, 113 (5) 61-9

Baumgarten P, Blank AE, Franz K, Hattingen E, Dunst M, Zeiner P, Hoffmann K, Bähr O, Mäder L, Goeppert B, Machein M, Seifert V, Steinbach JP, Plate KH, Harter PN & Mittelbronn M
Differential expression of vascular endothelial growth factor A, its receptors VEGFR-1, -2, and -3 and co-receptors neuropilin-1 and -2 does not predict bevacizumab response in human astrocytomas.
Neuro-oncology, 2016 Feb, 18 (2) 173-83

Liu J, Wang LN, Arzberger T & Zhu MW
Pathological Changes of von Economo Neuron and Fork Neuron in Neuropsychiatric Diseases.
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2016 Feb, 38 (1) 113-7

Minikel EV, Vallabh SM, Lek M, Estrada K, Samocha KE, Sathirapongsasuti JF, McLean CY, Tung JY, Yu LP, Gambetti P, Blevins J, Zhang S, Cohen Y, Chen W, Yamada M, Hamaguchi T, Sanjo N, Mizusawa H, Nakamura Y, Kitamoto T, Collins SJ, Boyd A, Will RG, Knight R, Ponto C, Zerr I, Kraus TF, Eigenbrod S, Giese A, Calero M, de Pedro-Cuesta J, Haïk S, Laplanche JL, Bouaziz-Amar E, Brandel JP, Capellari S, Parchi P, Poleggi A, Ladogana A, O'Donnell-Luria AH, Karczewski KJ, Marshall JL, Boehnke M, Laakso M, Mohlke KL, Kähler A, Chambert K, McCarroll S, Sullivan PF, Hultman CM, Purcell SM, Sklar P, van der Lee SJ, Rozemuller A, Jansen C, Hofman A, Kraaij R, van Rooij JG, Ikram MA, Uitterlinden AG, van Duijn CM, Exome Aggregation Consortium (ExAC), Daly MJ & MacArthur DG
Quantifying prion disease penetrance using large population control cohorts.
Science translational medicine, 2016 Jan 20, 8 (322) 322ra9

Niyazi M, Harter PN, Hattingen E, Rottler M, von Baumgarten L, Proescholdt M, Belka C, Lauber K & Mittelbronn M
Bevacizumab and radiotherapy for the treatment of glioblastoma: brothers in arms or unholy alliance?
Oncotarget, 2016 Jan 19, 7 (3) 2313-28

Blasel S, Zagorcic A, Jurcoane A, Bähr O, Wagner M, Harter PN & Hattingen E
Perfusion MRI in the Evaluation of Suspected Glioblastoma Recurrence.
Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2016, 26 (1) 116-23

Braczynski AK, Harter PN, Zeiner PS, Drott U, Tews DS, Preusse C, Penski C, Dunst M, Weis J, Stenzel W & Mittelbronn M
C5b-9 deposits on endomysial capillaries in non-dermatomyositis cases.
Neuromuscular disorders : NMD, 2016, 26 (4-5) 283-91

Ghio S, Kamp F, Cauchi R, Giese A & Vassallo N
Interaction of α-synuclein with biomembranes in Parkinson's disease--role of cardiolipin.
Progress in lipid research, 2016 Jan, 61 73-82

Kovacs GG, Ferrer I, Grinberg LT, Alafuzoff I, Attems J, Budka H, Cairns NJ, Crary JF, Duyckaerts C, Ghetti B, Halliday GM, Ironside JW, Love S, Mackenzie IR, Munoz DG, Murray ME, Nelson PT, Takahashi H, Trojanowski JQ, Ansorge O, Arzberger T, Baborie A, Beach TG, Bieniek KF, Bigio EH, Bodi I, Dugger BN, Feany M, Gelpi E, Gentleman SM, Giaccone G, Hatanpaa KJ, Heale R, Hof PR, Hofer M, Hortobágyi T, Jellinger K, Jicha GA, Ince P, Kofler J, Kövari E, Kril JJ, Mann DM, Matej R, McKee AC, McLean C, Milenkovic I, Montine TJ, Murayama S, Lee EB, Rahimi J, Rodriguez RD, Rozemüller A, Schneider JA, Schultz C, Seeley W, Seilhean D, Smith C, Tagliavini F, Takao M, Thal DR, Toledo JB, Tolnay M, Troncoso JC, Vinters HV, Weis S, Wharton SB, White CL, Wisniewski T, Woulfe JM, Yamada M & Dickson DW
Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy.
Acta neuropathologica, 2016 Jan, 131 (1) 87-102

Scholz A, Harter PN, Cremer S, Yalcin BH, Gurnik S, Yamaji M, Di Tacchio M, Sommer K, Baumgarten P, Bähr O, Steinbach JP, Trojan J, Glas M, Herrlinger U, Krex D, Meinhardt M, Weyerbrock A, Timmer M, Goldbrunner R, Deckert M, Braun C, Schittenhelm J, Frueh JT, Ullrich E, Mittelbronn M, Plate KH & Reiss Y
Endothelial cell-derived angiopoietin-2 is a therapeutic target in treatment-naive and bevacizumab-resistant glioblastoma.
EMBO molecular medicine, 2016 Jan 01, 8 (1) 39-57

Fellner L, Kuzdas-Wood D, Levin J, Ryazanov S, Leonov A, Griesinger C, Giese A, Wenning GK & Stefanova N
Anle138b Partly Ameliorates Motor Deficits Despite Failure of Neuroprotection in a Model of Advanced Multiple System Atrophy.
Frontiers in neuroscience, 2016, 10 99

Overhoff F, Brendel M, Jaworska A, Korzhova V, Delker A, Probst F, Focke C, Gildehaus FJ, Carlsen J, Baumann K, Haass C, Bartenstein P, Herms J & Rominger A
Automated Spatial Brain Normalization and Hindbrain White Matter Reference Tissue Give Improved [(18)F]-Florbetaben PET Quantitation in Alzheimer's Model Mice.
Frontiers in neuroscience, 2016, 10 45

Struebing FL, Lee RK, Williams RW & Geisert EE
Genetic Networks in Mouse Retinal Ganglion Cells.
Frontiers in genetics, 2016, 7 169

2015

Harter PN, Bernatz S, Scholz A, Zeiner PS, Zinke J, Kiyose M, Blasel S, Beschorner R, Senft C, Bender B, Ronellenfitsch MW, Wikman H, Glatzel M, Meinhardt M, Juratli TA, Steinbach JP, Plate KH, Wischhusen J, Weide B & Mittelbronn M
Distribution and prognostic relevance of tumor-infiltrating lymphocytes (TILs) and PD-1/PD-L1 immune checkpoints in human brain metastases.
Oncotarget, 2015 Dec 01, 6 (38) 40836-49

Roeber S, Müller-Sarnowski F, Kress J, Edbauer D, Kuhlmann T, Tüttelmann F, Schindler C, Winter P, Arzberger T, Müller U, Danek A & Kretzschmar HA
Three novel presenilin 1 mutations marking the wide spectrum of age at onset and clinical patterns in familial Alzheimer's disease.
Journal of neural transmission (Vienna, Austria : 1996), 2015 Dec, 122 (12) 1715-9

Wagner J, Krauss S, Shi S, Ryazanov S, Steffen J, Miklitz C, Leonov A, Kleinknecht A, Göricke B, Weishaupt JH, Weckbecker D, Reiner AM, Zinth W, Levin J, Ehninger D, Remy S, Kretzschmar HA, Griesinger C, Giese A & Fuhrmann M
Reducing tau aggregates with anle138b delays disease progression in a mouse model of tauopathies.
Acta neuropathologica, 2015 Nov, 130 (5) 619-31

Willem M, Tahirovic S, Busche MA, Ovsepian SV, Chafai M, Kootar S, Hornburg D, Evans LD, Moore S, Daria A, Hampel H, Müller V, Giudici C, Nuscher B, Wenninger-Weinzierl A, Kremmer E, Heneka MT, Thal DR, Giedraitis V, Lannfelt L, Müller U, Livesey FJ, Meissner F, Herms J, Konnerth A, Marie H & Haass C
η-Secretase processing of APP inhibits neuronal activity in the hippocampus.
Nature, 2015 Oct 15, 526 (7573) 443-7

Wagner M, Steinbacher J, Kraus TF, Michalakis S, Hackner B, Pfaffeneder T, Perera A, Müller M, Giese A, Kretzschmar HA & Carell T
Age-dependent levels of 5-methyl-, 5-hydroxymethyl-, and 5-formylcytosine in human and mouse brain tissues.
Angewandte Chemie (International ed. in English), 2015 Oct 12, 54 (42) 12511-4

Klinger F, Bajric M, Salzer I, Dorostkar MM, Khan D, Pollak DD, Kubista H, Boehm S & Koenig X
δ Subunit-containing GABAA receptors are preferred targets for the centrally acting analgesic flupirtine.
British journal of pharmacology, 2015 Oct, 172 (20) 4946-58

Levin J, Bak TH, Rominger A, Mille E, Arzberger T, Giese A, Ackl N, Lorenzl S, Bader B, Patzig M, Bötzel K & Danek A
The association of aphasia and right-sided motor impairment in corticobasal syndrome.
Journal of neurology, 2015 Oct, 262 (10) 2241-6

Brendel M, Jaworska A, Herms J, Trambauer J, Rötzer C, Gildehaus FJ, Carlsen J, Cumming P, Bylund J, Luebbers T, Bartenstein P, Steiner H, Haass C, Baumann K & Rominger A
Amyloid-PET predicts inhibition of de novo plaque formation upon chronic γ-secretase modulator treatment.
Molecular psychiatry, 2015 Oct, 20 (10) 1179-87

Brendel M, Jaworska A, Herms J, Trambauer J, Rötzer C, Gildehaus FJ, Carlsen J, Cumming P, Bylund J, Luebbers T, Bartenstein P, Steiner H, Haass C, Baumann K & Rominger A
Monitoring of chronic γ-secretase modulator treatment by serial amyloid-PET.
Molecular psychiatry, 2015 Oct, 20 (10) 1141

Roeber , Schludi MH, May S, Grässer FA, Rentzsch K, Kremmer E, Küpper C, Klopstock T, German Consortium for Frontotemporal Lobar Degeneration, Bavarian Brain Banking Alliance, Arzberger T & Edbauer D
Distribution of dipeptide repeat proteins in cellular models and C9orf72 mutation cases suggests link to transcriptional silencing.
Acta neuropathologica, 2015 Oct, 130 (4) 537-55

Sundstrøm T, Espedal H, Harter PN, Fasmer KE, Skaftnesmo KO, Horn S, Hodneland E, Mittelbronn M, Weide B, Beschorner R, Bender B, Rygh CB, Lund-Johansen M, Bjerkvig R & Thorsen F
Melanoma brain metastasis is independent of lactate dehydrogenase A expression.
Neuro-oncology, 2015 Oct, 17 (10) 1374-85

Schulte EC, Fukumori A, Mollenhauer B, Hor H, Arzberger T, Perneczky R, Kurz A, Diehl-Schmid J, Hüll M, Lichtner P, Eckstein G, Zimprich A, Haubenberger D, Pirker W, Brücke T, Bereznai B, Molnar MJ, Lorenzo-Betancor O, Pastor P, Peters A, Gieger C, Estivill X, Meitinger T, Kretzschmar HA, Trenkwalder C, Haass C & Winkelmann J
Rare variants in β-Amyloid precursor protein (APP) and Parkinson's disease.
European journal of human genetics : EJHG, 2015 Oct, 23 (10) 1328-33

Schludi MH, May S, Grässer FA, Rentzsch K, Kremmer E, Küpper C, Klopstock T, German Consortium for Frontotemporal Lobar Degeneration, Bavarian Brain Banking Alliance, Arzberger T & Edbauer D
Erratum to: Distribution of dipeptide repeat proteins in cellular models and C9orf72 mutation cases suggests link to transcriptional silencing.
Acta neuropathologica, 2015 Oct, 130 (4) 557-8

Liu G, Sgobio C, Gu X, Sun L, Lin X, Yu J, Parisiadou L, Xie C, Sastry N, Ding J, Lohr KM, Miller GW, Mateo Y, Lovinger DM & Cai H
Selective expression of Parkinson's disease-related Leucine-rich repeat kinase 2 G2019S missense mutation in midbrain dopaminergic neurons impairs dopamine release and dopaminergic gene expression.
Human molecular genetics, 2015 Sep 15, 24 (18) 5299-312

Shi S, Wagner J, Mitteregger-Kretzschmar G, Ryazanov S, Leonov A, Griesinger C & Giese A
Quantitative Real-Time Quaking-Induced Conversion Allows Monitoring of Disease-Modifying Therapy in the Urine of Prion-Infected Mice.
Journal of neuropathology and experimental neurology, 2015 Sep, 74 (9) 924-33

Deeg AA, Reiner AM, Schmidt F, Schueder F, Ryazanov S, Ruf VC, Giller K, Becker S, Leonov A, Griesinger C, Giese A & Zinth W
Anle138b and related compounds are aggregation specific fluorescence markers and reveal high affinity binding to α-synuclein aggregates.
Biochimica et biophysica acta, 2015 Sep, 1850 (9) 1884-90

Seo SW, Koeppen M, Bonney S, Gobel M, Thayer M, Harter PN, Ravid K, Eltzschig HK, Mittelbronn M, Walker L & Eckle T
Differential Tissue-Specific Function of Adora2b in Cardioprotection.
Journal of immunology (Baltimore, Md. : 1950), 2015 Aug 15, 195 (4) 1732-43

Blazquez-Llorca L, Hummel E, Zimmerman H, Zou C, Burgold S, Rietdorf J & Herms J
Correlation of two-photon in vivo imaging and FIB/SEM microscopy.
Journal of microscopy, 2015 Aug, 259 (2) 129-136

Kantelhardt SR, Hausen U, Kosterhon M, Amr AN, Gruber K & Giese A
Computer simulation and image guidance for individualised dynamic spinal stabilization.
International journal of computer assisted radiology and surgery, 2015 Aug, 10 (8) 1325-32

Bruch J, Kurz C, Vasiljevic A, Nicolino M, Arzberger T & Höglinger GU
Early Neurodegeneration in the Brain of a Child Without Functional PKR-like Endoplasmic Reticulum Kinase.
Journal of neuropathology and experimental neurology, 2015 Aug, 74 (8) 850-7

Reiter FP, Giessen-Jung C, Dorostkar MM, Ertl-Wagner B, Denk GU, Heck S, Rieger CT, Pfister HW & op den Winkel M
Miliary pattern of brain metastases - a case report of a hyperacute onset in a patient with malignant melanoma documented by magnetic resonance imaging.
Radiation oncology (London, England), 2015 Jul 19, 10 148

Meyronet D, Dorey A, Massoma P, Rey C, Alix E, Silva K, Perrin C, Quadrio I, Perret-Liaudet A, Streichenberger N, Thomasset N, Honnorat J, Arzberger T & Kretzschmar H
The workflow from post-mortem human brain sampling to cell microdissection: a Brain Net Europe study.
Journal of neural transmission (Vienna, Austria : 1996), 2015 Jul, 122 (7) 975-91

Strobel S, Grünblatt E, Riederer P, Heinsen H, Arzberger T, Al-Sarraj S, Troakes C, Ferrer I & Monoranu CM
Changes in the expression of genes related to neuroinflammation over the course of sporadic Alzheimer's disease progression: CX3CL1, TREM2, and PPARγ.
Journal of neural transmission (Vienna, Austria : 1996), 2015 Jul, 122 (7) 1069-76

Klioueva NM, Rademaker MC, Dexter DT, Al-Sarraj S, Seilhean D, Streichenberger N, Schmitz P, Bell JE, Ironside JW, Arzberger T & Huitinga I
BrainNet Europe's Code of Conduct for brain banking.
Journal of neural transmission (Vienna, Austria : 1996), 2015 Jul, 122 (7) 937-40

Thal DR, von Arnim CA, Griffin WS, Mrak RE, Walker L, Attems J & Arzberger T
Frontotemporal lobar degeneration FTLD-tau: preclinical lesions, vascular, and Alzheimer-related co-pathologies.
Journal of neural transmission (Vienna, Austria : 1996), 2015 Jul, 122 (7) 1007-18

Alafuzoff I, Pikkarainen M, Neumann M, Arzberger T, Al-Sarraj S, Bodi I, Bogdanovic N, Bugiani O, Ferrer I, Gelpi E, Gentleman S, Giaccone G, Graeber MB, Hortobagyi T, Ince PG, Ironside JW, Kavantzas N, King A, Korkolopoulou P, Kovács GG, Meyronet D, Monoranu C, Nilsson T, Parchi P, Patsouris E, Revesz T, Roggendorf W, Rozemuller A, Seilhean D, Streichenberger N, Thal DR, Wharton SB & Kretzschmar H
Neuropathological assessments of the pathology in frontotemporal lobar degeneration with TDP43-positive inclusions: an inter-laboratory study by the BrainNet Europe consortium.
Journal of neural transmission (Vienna, Austria : 1996), 2015 Jul, 122 (7) 957-72

Durrenberger PF, Fernando FS, Kashefi SN, Bonnert TP, Seilhean D, Nait-Oumesmar B, Schmitt A, Gebicke-Haerter PJ, Falkai P, Grünblatt E, Palkovits M, Arzberger T, Kretzschmar H, Dexter DT & Reynolds R
Common mechanisms in neurodegeneration and neuroinflammation: a BrainNet Europe gene expression microarray study.
Journal of neural transmission (Vienna, Austria : 1996), 2015 Jul, 122 (7) 1055-68

Edbauer D & Arzberger T
Brain banks still yield high interest rates.
Journal of neural transmission (Vienna, Austria : 1996), 2015 Jul, 122 (7) 935-6

Giese A & Arzberger T
In Memoriam: Hans A. Kretzschmar (1953–2014).
Journal of neural transmission (Vienna, Austria : 1996), 2015 Jul, 122 (7) 934-5

Henz S, Ackl N, Knels C, Rominger A, Flatz W, Teipel S, Huppertz HJ, Roeber S, Neumann M & Danek A
[A Pair of Siblings with a rare R5H-Mutation in Exon 1 of the MAPT-Gene].
Fortschritte der Neurologie-Psychiatrie, 2015 Jul, 83 (7) 397-401

Dorostkar MM, Zou C, Blazquez-Llorca L & Herms J
Analyzing dendritic spine pathology in Alzheimer's disease: problems and opportunities.
Acta neuropathologica, 2015 Jul, 130 (1) 1-19

Zeiner PS, Preusse C, Blank AE, Zachskorn C, Baumgarten P, Caspary L, Braczynski AK, Weissenberger J, Bratzke H, Reiß S, Pennartz S, Winkelmann R, Senft C, Plate KH, Wischhusen J, Stenzel W, Harter PN & Mittelbronn M
MIF Receptor CD74 is Restricted to Microglia/Macrophages, Associated with a M1-Polarized Immune Milieu and Prolonged Patient Survival in Gliomas.
Brain pathology (Zurich, Switzerland), 2015 Jul, 25 (4) 491-504

Alafuzoff I, Pikkarainen M, Neumann M, Arzberger T, Al-Sarraj S, Bodi I, Bogdanovic N, Bugiani O, Ferrer I, Gelpi E, Gentleman S, Giaccone G, Graeber MB, Hortobagyi T, Ince PG, Ironside JW, Kavantzas N, King A, Korkolopoulou P, Kovács GG, Meyronet D, Monoranu C, Nilsson T, Parchi P, Patsouris E, Revesz T, Roggendorf W, Rozemuller A, Seilhean D, Streichenberger N, Thal DR, Wharton SB & Kretzschmar H
Erratum to: Neuropathological assessments of the pathology in frontotemporal lobar degeneration with TDP43-positive inclusions: an inter-laboratory study by the BrainNet Europe consortium.
Journal of neural transmission (Vienna, Austria : 1996), 2015 Jul, 122 (7) 973-4

Kouri N, Ross OA, Dombroski B, Younkin CS, Serie DJ, Soto-Ortolaza A, Baker M, Finch NCA, Yoon H, Kim J, Fujioka S, McLean CA, Ghetti B, Spina S, Cantwell LB, Farlow MR, Grafman J, Huey ED, Ryung Han M, Beecher S, Geller ET, Kretzschmar HA, Roeber S, Gearing M, Juncos JL, Vonsattel JPG, Van Deerlin VM, Grossman M, Hurtig HI, Gross RG, Arnold SE, Trojanowski JQ, Lee VM, Wenning GK, White CL, Höglinger GU, Müller U, Devlin B, Golbe LI, Crook J, Parisi JE, Boeve BF, Josephs KA, Wszolek ZK, Uitti RJ, Graff-Radford NR, Litvan I, Younkin SG, Wang LS, Ertekin-Taner N, Rademakers R, Hakonarsen H, Schellenberg GD & Dickson DW
Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy.
Nature communications, 2015 Jun 16, 6 7247

Thiepold AL, Luger S, Wagner M, Filmann N, Ronellenfitsch MW, Harter PN, Braczynski AK, Dützmann S, Hattingen E, Steinbach JP, Senft C, Rieger J & Bähr O
Perioperative cerebral ischemia promote infiltrative recurrence in glioblastoma.
Oncotarget, 2015 Jun 10, 6 (16) 14537-44

Zou C, Montagna E, Shi Y, Peters F, Blazquez-Llorca L, Shi S, Filser S, Dorostkar MM & Herms J
Intraneuronal APP and extracellular Aβ independently cause dendritic spine pathology in transgenic mouse models of Alzheimer's disease.
Acta neuropathologica, 2015 Jun, 129 (6) 909-20

Kunadt M, Eckermann K, Stuendl A, Gong J, Russo B, Strauss K, Rai S, Kügler S, Falomir Lockhart L, Schwalbe M, Krumova P, Oliveira LM, Bähr M, Möbius W, Levin J, Giese A, Kruse N, Mollenhauer B, Geiss-Friedlander R, Ludolph AC, Freischmidt A, Feiler MS, Danzer KM, Zweckstetter M, Jovin TM, Simons M, Weishaupt JH & Schneider A
Extracellular vesicle sorting of α-Synuclein is regulated by sumoylation.
Acta neuropathologica, 2015 May, 129 (5) 695-713

Thon N, Kunz M, Lemke L, Jansen NL, Eigenbrod S, Kreth S, Lutz J, Egensperger R, Giese A, Herms J, Weller M, Kretzschmar H, Tonn JC, la Fougère C & Kreth FW
Dynamic 18F-FET PET in suspected WHO grade II gliomas defines distinct biological subgroups with different clinical courses.
International journal of cancer, 2015 May 01, 136 (9) 2132-45

Filser S, Ovsepian SV, Masana M, Blazquez-Llorca L, Brandt Elvang A, Volbracht C, Müller MB, Jung CK & Herms J
Pharmacological inhibition of BACE1 impairs synaptic plasticity and cognitive functions.
Biological psychiatry, 2015 Apr 15, 77 (8) 729-39

Ochs SM, Dorostkar MM, Aramuni G, Schön C, Filser S, Pöschl J, Kremer A, Van Leuven F, Ovsepian SV & Herms J
Loss of neuronal GSK3β reduces dendritic spine stability and attenuates excitatory synaptic transmission via β-catenin.
Molecular psychiatry, 2015 Apr, 20 (4) 482-9

Eggers SD, Horn AK, Roeber S, Härtig W, Nair G, Reich DS & Leigh RJ
Saccadic palsy following cardiac surgery: a review and new hypothesis.
Annals of the New York Academy of Sciences, 2015 Apr, 1343 (1) 113-9

Ortiz-Pelaez A, Georgiadou S, Simmons MM, Windl O, Dawson M, Arnold ME, Neocleous P & Papasavva-Stylianou P
Allelic variants at codon 146 in the PRNP gene show significant differences in the risk for natural scrapie in Cypriot goats.
Epidemiology and infection, 2015 Apr, 143 (6) 1304-10

Yousefi BH, Manook A, Grimmer T, Arzberger T, von Reutern B, Henriksen G, Drzezga A, Förster S, Schwaiger M & Wester HJ
Characterization and first human investigation of FIBT, a novel fluorinated Aβ plaque neuroimaging PET radioligand.
ACS chemical neuroscience, 2015 Mar 18, 6 (3) 428-37

Wollenweber FA, Hanecker P, Bayer-Karpinska A, Malik R, Bäzner H, Moreton F, Muir KW, Müller S, Giese A, Opherk C, Dichgans M, Haffner C & Duering M
Cysteine-sparing CADASIL mutations in NOTCH3 show proaggregatory properties in vitro.
Stroke, 2015 Mar, 46 (3) 786-92

Spadaro M, Gerdes LA, Mayer MC, Ertl-Wagner B, Laurent S, Krumbholz M, Breithaupt C, Högen T, Straube A, Giese A, Hohlfeld R, Lassmann H, Meinl E & Kümpfel T
Histopathology and clinical course of MOG-antibody-associated encephalomyelitis.
Annals of clinical and translational neurology, 2015 Mar, 2 (3) 295-301

Doberstein K, Harter PN, Haberkorn U, Bretz NP, Arnold B, Carretero R, Moldenhauer G, Mittelbronn M & Altevogt P
Antibody therapy to human L1CAM in a transgenic mouse model blocks local tumor growth but induces EMT.
International journal of cancer, 2015 Mar 01, 136 (5) E326-39

Zinke J, Schneider FT, Harter PN, Thom S, Ziegler N, Toftgård R, Plate KH & Liebner S
β-Catenin-Gli1 interaction regulates proliferation and tumor growth in medulloblastoma.
Molecular cancer, 2015 Feb 03, 14 (1) 17

Blank AE, Baumgarten P, Zeiner P, Zachskorn C, Löffler C, Schittenhelm J, Czupalla CJ, Capper D, Plate KH, Harter PN & Mittelbronn M
Tumour necrosis factor receptor superfamily member 9 (TNFRSF9) is up-regulated in reactive astrocytes in human gliomas.
Neuropathology and applied neurobiology, 2015 Feb, 41 (2) e56-67

Harter PN, Baumgarten P, Zinke J, Schilling K, Baader S, Hartmetz AK, Schittenhelm J, Beschorner R, Liebner S, Schulte D, Plate KH, Gutwein P, Korshunov A, Pfister SM, Jones DT, Doberstein K & Mittelbronn M
Paired box gene 8 (PAX8) expression is associated with sonic hedgehog (SHH)/wingless int (WNT) subtypes, desmoplastic histology and patient survival in human medulloblastomas.
Neuropathology and applied neurobiology, 2015 Feb, 41 (2) 165-79

Michaelis M, Agha B, Rothweiler F, Löschmann N, Voges Y, Mittelbronn M, Starzetz T, Harter PN, Abhari BA, Fulda S, Westermann F, Riecken K, Spek S, Langer K, Wiese M, Dirks WG, Zehner R, Cinatl J, Wass MN & Cinatl J
Identification of flubendazole as potential anti-neuroblastoma compound in a large cell line screen.
Scientific reports, 2015 Feb 03, 5 8202

Braczynski AK, Vlaho S, Müller K, Wittig I, Blank AE, Tews DS, Drott U, Kleinle S, Abicht A, Horvath R, Plate KH, Stenzel W, Goebel HH, Schulze A, Harter PN, Kieslich M & Mittelbronn M
ATP synthase deficiency due to TMEM70 mutation leads to ultrastructural mitochondrial degeneration and is amenable to treatment.
BioMed research international, 2015, 2015 462592

Tichy J, Zinke J, Bunz B, Meyermann R, Harter PN & Mittelbronn M
Expression Profile of Sonic Hedgehog Pathway Members in the Developing Human Fetal Brain.
BioMed research international, 2015, 2015 494269

Eggers SD, Horn AK, Roeber S, Härtig W, Nair G, Reich DS & Leigh RJ
Saccadic Palsy following Cardiac Surgery: Possible Role of Perineuronal Nets.
PloS one, 2015, 10 (7) e0132075

Harter PN, Jennewein L, Baumgarten P, Ilina E, Burger MC, Thiepold AL, Tichy J, Zörnig M, Senft C, Steinbach JP, Mittelbronn M & Ronellenfitsch MW
Immunohistochemical Assessment of Phosphorylated mTORC1-Pathway Proteins in Human Brain Tumors.
PloS one, 2015, 10 (5) e0127123

Jung CK, Keppler K, Steinbach S, Blazquez-Llorca L & Herms J
Fibrillar amyloid plaque formation precedes microglial activation.
PloS one, 2015, 10 (3) e0119768

Struebing FL & Geisert EE
What Animal Models Can Tell Us About Glaucoma.
Progress in molecular biology and translational science, 2015, 134 365-80

Tark D, Kim H, Neale MH, Kim M, Sohn H, Lee Y, Cho I, Joo Y & Windl O
Generation of a persistently infected MDBK cell line with natural bovine spongiform encephalopathy (BSE).
PloS one, 2015, 10 (2) e0115939

Sastry N, Zheng W, Liu G, Wang H, Chen X, Cai M, Contractor P, Sgobio C, Sun L, Xie C & Cai H
No apparent transmission of transgenic α-synuclein into nigrostriatal dopaminergic neurons in multiple mouse models.
Translational neurodegeneration, 2015, 4 23

Brendel M, Jaworska A, Grießinger E, Rötzer C, Burgold S, Gildehaus FJ, Carlsen J, Cumming P, Baumann K, Haass C, Steiner H, Bartenstein P, Herms J & Rominger A
Cross-sectional comparison of small animal [18F]-florbetaben amyloid-PET between transgenic AD mouse models.
PloS one, 2015, 10 (2) e0116678

Zhu MW, Liu J, Arzberger T, Wang LN & Wang ZF
Typical or atypical progressive supranuclear palsy: a comparative clinicopathologic study of three Chinese cases.
International journal of clinical and experimental pathology, 2015, 8 (1) 867-74

Fack F, Espedal H, Keunen O, Golebiewska A, Obad N, Harter PN, Mittelbronn M, Bähr O, Weyerbrock A, Stuhr L, Miletic H, Sakariassen PØ, Stieber D, Rygh CB, Lund-Johansen M, Zheng L, Gottlieb E, Niclou SP & Bjerkvig R
Bevacizumab treatment induces metabolic adaptation toward anaerobic metabolism in glioblastomas.
Acta neuropathologica, 2015 Jan, 129 (1) 115-31

2014

Honarnejad K, Daschner A, Gehring AP, Szybinska A, Giese A, Kuznicki J, Bracher F & Herms J
Identification of tetrahydrocarbazoles as novel multifactorial drug candidates for treatment of Alzheimer's disease.
Translational psychiatry, 2014 Dec 16, 4 (12) e489

Respondek G, Stamelou M, Kurz C, Ferguson LW, Rajput A, Chiu WZ, van Swieten JC, Troakes C, Al Sarraj S, Gelpi E, Gaig C, Tolosa E, Oertel WH, Giese A, Roeber S, Arzberger T, Wagenpfeil S, Höglinger GU & Movement Disorder Society-endorsed PSP Study Group
The phenotypic spectrum of progressive supranuclear palsy: a retrospective multicenter study of 100 definite cases.
Movement disorders : official journal of the Movement Disorder Society, 2014 Dec, 29 (14) 1758-66

Eichenmüller M, Trippel F, Kreuder M, Beck A, Schwarzmayr T, Häberle B, Cairo S, Leuschner I, von Schweinitz D, Strom TM & Kappler R
The genomic landscape of hepatoblastoma and their progenies with HCC-like features.
Journal of hepatology, 2014 Dec, 61 (6) 1312-20

Dorostkar MM, Burgold S, Filser S, Barghorn S, Schmidt B, Anumala UR, Hillen H, Klein C & Herms J
Immunotherapy alleviates amyloid-associated synaptic pathology in an Alzheimer's disease mouse model.
Brain : a journal of neurology, 2014 Dec, 137 (Pt 12) 3319-26

Templeton JP, Struebing FL, Lemmon A & Geisert EE
ImagePAD, a novel counting application for the Apple iPad, used to quantify axons in the mouse optic nerve.
Experimental eye research, 2014 Nov, 128 102-8

Pendolino V, Bagetta V, Ghiglieri V, Sgobio C, Morelli E, Poggini S, Branchi I, Latagliata EC, Pascucci T, Puglisi-Allegra S, Calabresi P & Picconi B
l-DOPA reverses the impairment of Dentate Gyrus LTD in experimental parkinsonism via β-adrenergic receptors.
Experimental neurology, 2014 Nov, 261 377-85

Balermpas P, Rödel F, Liberz R, Oppermann J, Wagenblast J, Ghanaati S, Harter PN, Mittelbronn M, Weiss C, Rödel C & Fokas E
Head and neck cancer relapse after chemoradiotherapy correlates with CD163+ macrophages in primary tumour and CD11b+ myeloid cells in recurrences.
British journal of cancer, 2014 Oct 14, 111 (8) 1509-18

May S, Hornburg D, Schludi MH, Arzberger T, Rentzsch K, Schwenk BM, Grässer FA, Mori K, Kremmer E, Banzhaf-Strathmann J, Mann M, Meissner F & Edbauer D
C9orf72 FTLD/ALS-associated Gly-Ala dipeptide repeat proteins cause neuronal toxicity and Unc119 sequestration.
Acta neuropathologica, 2014 Oct, 128 (4) 485-503

Kleele T, Marinković P, Williams PR, Stern S, Weigand EE, Engerer P, Naumann R, Hartmann J, Karl RM, Bradke F, Bishop D, Herms J, Konnerth A, Kerschensteiner M, Godinho L & Misgeld T
An assay to image neuronal microtubule dynamics in mice.
Nature communications, 2014 Sep 12, 5 4827

Ovsepian SV, Antyborzec I, O'Leary VB, Zaborszky L, Herms J & Oliver Dolly J
Neurotrophin receptor p75 mediates the uptake of the amyloid beta (Aβ) peptide, guiding it to lysosomes for degradation in basal forebrain cholinergic neurons.
Brain structure & function, 2014 Sep, 219 (5) 1527-41

Risolino M, Mandia N, Iavarone F, Dardaei L, Longobardi E, Fernandez S, Talotta F, Bianchi F, Pisati F, Spaggiari L, Harter PN, Mittelbronn M, Schulte D, Incoronato M, Di Fiore PP, Blasi F & Verde P
Transcription factor PREP1 induces EMT and metastasis by controlling the TGF-β-SMAD3 pathway in non-small cell lung adenocarcinoma.
Proceedings of the National Academy of Sciences of the United States of America, 2014 Sep 09, 111 (36) E3775-84

Kast J, Hanecker P, Beaufort N, Giese A, Joutel A, Dichgans M, Opherk C & Haffner C
Sequestration of latent TGF-β binding protein 1 into CADASIL-related Notch3-ECD deposits.
Acta neuropathologica communications, 2014 Aug 13, 2 96

Eigenbrod S, Trabold R, Brucker D, Erös C, Egensperger R, La Fougere C, Göbel W, Rühm A, Kretzschmar HA, Tonn JC, Herms J, Giese A & Kreth FW
Molecular stereotactic biopsy technique improves diagnostic accuracy and enables personalized treatment strategies in glioma patients.
Acta neurochirurgica, 2014 Aug, 156 (8) 1427-40

Craggs LJ, Yamamoto Y, Ihara M, Fenwick R, Burke M, Oakley AE, Roeber S, Duering M, Kretzschmar H & Kalaria RN
White matter pathology and disconnection in the frontal lobe in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).
Neuropathology and applied neurobiology, 2014 Aug, 40 (5) 591-602

Banzhaf-Strathmann J, Benito E, May S, Arzberger T, Tahirovic S, Kretzschmar H, Fischer A & Edbauer D
MicroRNA-125b induces tau hyperphosphorylation and cognitive deficits in Alzheimer's disease.
The EMBO journal, 2014 Aug 01, 33 (15) 1667-80

Bähr O, Harter PN, Weise LM, You SJ, Mittelbronn M, Ronellenfitsch MW, Rieger J, Steinbach JP & Hattingen E
Sustained focal antitumor activity of bevacizumab in recurrent glioblastoma.
Neurology, 2014 Jul 15, 83 (3) 227-34

Levin J, Tiedt S, Arzberger T, Biskup S, Schuberth M, Stenglein-Krapf G, Kreth FW, Högen T, la Fougère C, Linn J, van der Knaap MS, Giese A, Kretzschmar HA & Danek A
Diffuse leukoencephalopathy with spheroids: biopsy findings and a novel mutation.
Clinical neurology and neurosurgery, 2014 Jul, 122 113-5

Arzberger , Schottlaender LV, Houlden H & Multiple-System Atrophy (MSA) Brain Bank Collaboration
Mutant COQ2 in multiple-system atrophy.
The New England journal of medicine, 2014 Jul 03, 371 (1) 81

Sellmann C, Villarín Pildaín L, Schmitt A, Leonardi-Essmann F, Durrenberger PF, Spanagel R, Arzberger T, Kretzschmar H, Zink M, Gruber O, Herrera-Marschitz M, Reynolds R, Falkai P, Gebicke-Haerter PJ & Matthäus F
Gene expression in superior temporal cortex of schizophrenia patients.
European archives of psychiatry and clinical neuroscience, 2014 Jun, 264 (4) 297-309

Neuner J, Ovsepian SV, Dorostkar M, Filser S, Gupta A, Michalakis S, Biel M & Herms J
Pathological α-synuclein impairs adult-born granule cell development and functional integration in the olfactory bulb.
Nature communications, 2014 May 28, 5 3915

Levin J, Schmidt F, Boehm C, Prix C, Bötzel K, Ryazanov S, Leonov A, Griesinger C & Giese A
The oligomer modulator anle138b inhibits disease progression in a Parkinson mouse model even with treatment started after disease onset.
Acta neuropathologica, 2014 May, 127 (5) 779-80

Gutenberg A, Nischwitz MD, Gunawan B, Enders C, Jung K, Bergmann M, Feiden W, Egensperger R, Keyvani K, Stolke D, Sure U, Schroeder HW, Warzok R, Schober R, Meixensberger J, Paulus W, Wassmann H, Stummer W, Blumcke I, Buchfelder M, van Landeghem FK, Vajkoczy P, Günther M, Bedke J, Giese A, Rohde V, Brück W, Füzesi L & Sander B
Predictive chromosomal clusters of synchronous and metachronous brain metastases in clear cell renal cell carcinoma.
Cancer genetics, 2014 May, 207 (5) 206-13

Pantazis G, Harter PN, Capper D, Kohlhof P, Mittelbronn M & Schittenhelm J
The embryonic stem cell factor UTF1 serves as a reliable diagnostic marker for germinomas.
Pathology, 2014 Apr, 46 (3) 225-9

Quick J, Gessler F, Dützmann S, Hattingen E, Harter PN, Weise LM, Franz K, Seifert V & Senft C
Benefit of tumor resection for recurrent glioblastoma.
Journal of neuro-oncology, 2014 Apr, 117 (2) 365-72

Schuberth M, Levin J, Sawalhe D, Schwarzkopf R, von Baumgarten L, Ertl-Wagner B, Rominger A, Arzberger T, Kretzschmar HA, Froböse T, Diehl-Schmid J, Biskup S & Danek A
[Hereditary diffuse leukencephalopathy with spheroids: a microgliopathy due to CSF1 receptor impairment].
Der Nervenarzt, 2014 Apr, 85 (4) 465-70

Herms J
In memoriam: Hans A. Kretzschmar (1953-2014).
Brain pathology (Zurich, Switzerland), 2014 Apr, 24 (3) 311-2

Scheil-Bertram S, Kappler R, von Baer A, Hartwig E, Sarkar M, Serra M, Brüderlein S, Westhoff B, Melzner I, Bassaly B, Herms J, Hugo HH, Schulte M & Möller P
Molecular profiling of chordoma.
International journal of oncology, 2014 Apr, 44 (4) 1041-55

Brouwer MC, Meijers JC, Baas F, van der Ende A, Pfister HW, Giese A, van de Beek D & Koedel U
Plasminogen activator inhibitor-1 influences cerebrovascular complications and death in pneumococcal meningitis.
Acta neuropathologica, 2014 Apr, 127 (4) 553-64

Burgold S, Filser S, Dorostkar MM, Schmidt B & Herms J
In vivo imaging reveals sigmoidal growth kinetic of β-amyloid plaques.
Acta neuropathologica communications, 2014 Mar 28, 2 30

Parisiadou L, Yu J, Sgobio C, Xie C, Liu G, Sun L, Gu XL, Lin X, Crowley NA, Lovinger DM & Cai H
LRRK2 regulates synaptogenesis and dopamine receptor activation through modulation of PKA activity.
Nature neuroscience, 2014 Mar, 17 (3) 367-76

Leidel F, Eiden M, Geissen M, Hirschberger T, Tavan P, Giese A, Kretzschmar HA, Schätzl H & Groschup MH
Piperazine derivatives inhibit PrP/PrP(res) propagation in vitro and in vivo.
Biochemical and biophysical research communications, 2014 Feb 28, 445 (1) 23-9

Neuner J, Filser S, Michalakis S, Biel M & Herms J
A30P α-Synuclein interferes with the stable integration of adult-born neurons into the olfactory network.
Scientific reports, 2014 Feb 03, 4 3931

Baumgarten P, Harter PN, Tönjes M, Capper D, Blank AE, Sahm F, von Deimling A, Kolluru V, Schwamb B, Rabenhorst U, Starzetz T, Kögel D, Rieker RJ, Plate KH, Ohgaki H, Radlwimmer B, Zörnig M & Mittelbronn M
Loss of FUBP1 expression in gliomas predicts FUBP1 mutation and is associated with oligodendroglial differentiation, IDH1 mutation and 1p/19q loss of heterozygosity.
Neuropathology and applied neurobiology, 2014 Feb, 40 (2) 205-16

Götzl JK, Mori K, Damme M, Fellerer K, Tahirovic S, Kleinberger G, Janssens J, van der Zee J, Lang CM, Kremmer E, Martin JJ, Engelborghs S, Kretzschmar HA, Arzberger T, Van Broeckhoven C, Haass C & Capell A
Common pathobiochemical hallmarks of progranulin-associated frontotemporal lobar degeneration and neuronal ceroid lipofuscinosis.
Acta neuropathologica, 2014, 127 (6) 845-60

Nübling GS, Levin J, Bader B, Lorenzl S, Hillmer A, Högen T, Kamp F & Giese A
Modelling Ser129 phosphorylation inhibits membrane binding of pore-forming alpha-synuclein oligomers.
PloS one, 2014, 9 (6) e98906

Weise LM, Harter PN, Eibach S, Braczynski AK, Dunst M, Rieger J, Bähr O, Hattingen E, Steinbach JP, Plate KH, Seifert V & Mittelbronn M
Confounding factors in diagnostics of MGMT promoter methylation status in glioblastomas in stereotactic biopsies.
Stereotactic and functional neurosurgery, 2014, 92 (3) 129-39

Fischer S, Ronellenfitsch MW, Thiepold AL, Harter PN, Reichert S, Kögel D, Paschke R, Mittelbronn M, Weller M, Steinbach JP, Fulda S & Bähr O
Hypoxia enhances the antiglioma cytotoxicity of B10, a glycosylated derivative of betulinic acid.
PloS one, 2014, 9 (4) e94921

Harter PN, Zinke J, Scholz A, Tichy J, Zachskorn C, Kvasnicka HM, Goeppert B, Delloye-Bourgeois C, Hattingen E, Senft C, Steinbach JP, Plate KH, Mehlen P, Schulte D & Mittelbronn M
Netrin-1 expression is an independent prognostic factor for poor patient survival in brain metastases.
PloS one, 2014, 9 (3) e92311

Gerschütz A, Heinsen H, Grünblatt E, Wagner AK, Bartl J, Meissner C, Fallgatter AJ, Al-Sarraj S, Troakes C, Ferrer I, Arzberger T, Deckert J, Riederer P, Fischer M, Tatschner T & Monoranu CM
Neuron-specific alterations in signal transduction pathways associated with Alzheimer's disease.
Journal of Alzheimer's disease : JAD, 2014, 40 (1) 135-42

Mittelbronn M, Baumgarten P, Harter PN & Plate KH
Analysis of cerebral angiogenesis in human glioblastomas.
Methods in molecular biology (Clifton, N.J.), 2014, 1135 187-203

Brendel M, Delker A, Rötzer C, Böning G, Carlsen J, Cyran C, Mille E, Gildehaus FJ, Cumming P, Baumann K, Steiner H, Haass C, Herms J, Bartenstein P & Rominger A
Impact of partial volume effect correction on cerebral β-amyloid imaging in APP-Swe mice using [(18)F]-florbetaben PET.
NeuroImage, 2014 Jan 01, 84 843-53

2013

Thorsen F, Fite B, Mahakian LM, Seo JW, Qin S, Harrison V, Johnson S, Ingham E, Caskey C, Sundstrøm T, Meade TJ, Harter PN, Skaftnesmo KO & Ferrara KW
Multimodal imaging enables early detection and characterization of changes in tumor permeability of brain metastases.
Journal of controlled release : official journal of the Controlled Release Society, 2013 Dec 28, 172 (3) 812-22

Hoffmann NA, Dorostkar MM, Blumenstock S, Goedert M & Herms J
Impaired plasticity of cortical dendritic spines in P301S tau transgenic mice.
Acta neuropathologica communications, 2013 Dec 17, 1 82

Gerschütz A, Heinsen H, Grünblatt E, Wagner AK, Bartl J, Meissner C, Fallgatter AJ, Al-Sarraj S, Troakes C, Ferrer I, Arzberger T, Deckert J, Riederer P, Fischer M, Tatschner T & Monoranu CM
Neuron-specific mitochondrial DNA deletion levels in sporadic Alzheimer's disease.
Current Alzheimer research, 2013 Dec, 10 (10) 1041-6

Mori K, Arzberger T, Grässer FA, Gijselinck I, May S, Rentzsch K, Weng SM, Schludi MH, van der Zee J, Cruts M, Van Broeckhoven C, Kremmer E, Kretzschmar HA, Haass C & Edbauer D
Bidirectional transcripts of the expanded C9orf72 hexanucleotide repeat are translated into aggregating dipeptide repeat proteins.
Acta neuropathologica, 2013 Dec, 126 (6) 881-93

Mackenzie IR, Arzberger T, Kremmer E, Troost D, Lorenzl S, Mori K, Weng SM, Haass C, Kretzschmar HA, Edbauer D & Neumann M
Dipeptide repeat protein pathology in C9ORF72 mutation cases: clinico-pathological correlations.
Acta neuropathologica, 2013 Dec, 126 (6) 859-79

Honarnejad K, Kirsch AK, Daschner A, Szybinska A, Kuznicki J & Herms J
FRET-based calcium imaging: a tool for high-throughput/content phenotypic drug screening in Alzheimer disease.
Journal of biomolecular screening, 2013 Dec, 18 (10) 1309-20

Griffiths PC, Plater JM, Chave A, Jayasena D, Tout AC, Rice PB, Vickery CM, Spiropoulos J, Stack MJ & Windl O
Overexpression of chimaeric murine/ovine PrP (A136H154Q171) in transgenic mice facilitates transmission and differentiation of ruminant prions.
The Journal of general virology, 2013 Nov, 94 (Pt 11) 2577-2586

Camilleri A, Zarb C, Caruana M, Ostermeier U, Ghio S, Högen T, Schmidt F, Giese A & Vassallo N
Mitochondrial membrane permeabilisation by amyloid aggregates and protection by polyphenols.
Biochimica et biophysica acta, 2013 Nov, 1828 (11) 2532-43

Harter PN, Dützmann S, Drott U, Zachskorn C, Hattingen E, Capper D, Gessler F, Senft C, Seifert V, Plate KH, Kögel D & Mittelbronn M
Anti-tissue factor (TF9-10H10) treatment reduces tumor cell invasiveness in a novel migratory glioma model.
Neuropathology : official journal of the Japanese Society of Neuropathology, 2013 Oct, 33 (5) 515-25

Sundal C, Fujioka S, Van Gerpen JA, Wider C, Nicholson AM, Baker M, Shuster EA, Aasly J, Spina S, Ghetti B, Roeber S, Garbern J, Tselis A, Swerdlow RH, Miller BB, Borjesson-Hanson A, Uitti RJ, Ross OA, Stoessl AJ, Rademakers R, Josephs KA, Dickson DW, Broderick D & Wszolek ZK
Parkinsonian features in hereditary diffuse leukoencephalopathy with spheroids (HDLS) and CSF1R mutations.
Parkinsonism & related disorders, 2013 Oct, 19 (10) 869-77

Högen T, Demel C, Giese A, Angele B, Pfister HW, Koedel U & Klein M
Adjunctive N-acetyl-L-cysteine in treatment of murine pneumococcal meningitis.
Antimicrobial agents and chemotherapy, 2013 Oct, 57 (10) 4825-30

Füllhase C, Hennenberg M, Giese A, Schmidt M, Strittmatter F, Soler R, Gratzke C, Andersson KE & Stief C
Presence of phosphodiesterase type 5 in the spinal cord and its involvement in bladder outflow obstruction related bladder overactivity.
The Journal of urology, 2013 Oct, 190 (4) 1430-5

Goeppert B, Schmidt CR, Geiselhart L, Dutruel C, Capper D, Renner M, Vogel MN, Zachskorn C, Zinke J, Campos B, Schmezer P, Popanda O, Wick W, Weller M, Meyermann R, Schittenhelm J, Harter PN, Simon P, Weichert W, Schirmacher P, Plass C & Mittelbronn M
Differential expression of the tumor suppressor A-kinase anchor protein 12 in human diffuse and pilocytic astrocytomas is regulated by promoter methylation.
Journal of neuropathology and experimental neurology, 2013 Oct, 72 (10) 933-41

Saverioni D, Notari S, Capellari S, Poggiolini I, Giese A, Kretzschmar HA & Parchi P
Analyses of protease resistance and aggregation state of abnormal prion protein across the spectrum of human prions.
The Journal of biological chemistry, 2013 Sep 27, 288 (39) 27972-85

Anumala UR, Gu J, Lo Monte F, Kramer T, Heyny-von Haußen R, Hölzer J, Goetschy-Meyer V, Schön C, Mall G, Hilger I, Czech C, Herms J & Schmidt B
Fluorescent rhodanine-3-acetic acids visualize neurofibrillary tangles in Alzheimer's disease brains.
Bioorganic & medicinal chemistry, 2013 Sep 01, 21 (17) 5139-44

Baumgarten P, Brokinkel B, Zinke J, Zachskorn C, Ebel H, Albert FK, Stummer W, Plate KH, Harter PN, Hasselblatt M & Mittelbronn M
Expression of vascular endothelial growth factor (VEGF) and its receptors VEGFR1 and VEGFR2 in primary and recurrent WHO grade III meningiomas.
Histology and histopathology, 2013 Sep, 28 (9) 1157-66

Blasel S, Jurcoane A, Bähr O, Weise L, Harter PN & Hattingen E
MR perfusion in and around the contrast-enhancement of primary CNS lymphomas.
Journal of neuro-oncology, 2013 Aug, 114 (1) 127-34

Roeber , Stutzbach LD, Xie SX, Naj AC, Albin R, Gilman S, PSP Genetics Study Group, Lee VM, Trojanowski JQ, Devlin B & Schellenberg GD
The unfolded protein response is activated in disease-affected brain regions in progressive supranuclear palsy and Alzheimer's disease.
Acta neuropathologica communications, 2013 Jul 06, 1 31

Varges D, Schulz-Schaeffer WJ, Wemheuer WM, Damman I, Schmitz M, Cramm M, Kallenberg K, Shirneshan K, Elkenani M, Markwort S, Faist M, Kohlhase J, Windl O & Zerr I
Spongiform encephalopathy in siblings with no evidence of protease-resistant prion protein or a mutation in the prion protein gene.
Journal of neurology, 2013 Jul, 260 (7) 1871-9

Rominger A, Brendel M, Burgold S, Keppler K, Baumann K, Xiong G, Mille E, Gildehaus FJ, Carlsen J, Schlichtiger J, Niedermoser S, Wängler B, Cumming P, Steiner H, Herms J, Haass C & Bartenstein P
Longitudinal assessment of cerebral β-amyloid deposition in mice overexpressing Swedish mutant β-amyloid precursor protein using 18F-florbetaben PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2013 Jul, 54 (7) 1127-34

Kastrup M, Powollik R, Balzer F, Röber S, Ahlborn R, von Dossow-Hanfstingl V, Wernecke KD & Spies CD
Predictive ability of the stability and workload index for transfer score to predict unplanned readmissions after ICU discharge.
Critical care medicine, 2013 Jul, 41 (7) 1608-15

Wagner J, Ryazanov S, Leonov A, Levin J, Shi S, Schmidt F, Prix C, Pan-Montojo F, Bertsch U, Mitteregger-Kretzschmar G, Geissen M, Eiden M, Leidel F, Hirschberger T, Deeg AA, Krauth JJ, Zinth W, Tavan P, Pilger J, Zweckstetter M, Frank T, Bähr M, Weishaupt JH, Uhr M, Urlaub H, Teichmann U, Samwer M, Bötzel K, Groschup M, Kretzschmar H, Griesinger C & Giese A
Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease.
Acta neuropathologica, 2013 Jun, 125 (6) 795-813

Kreth S, Limbeck E, Hinske LC, Schütz SV, Thon N, Hoefig K, Egensperger R & Kreth FW
In human glioblastomas transcript elongation by alternative polyadenylation and miRNA targeting is a potent mechanism of MGMT silencing.
Acta neuropathologica, 2013 May, 125 (5) 671-81

Nikolic I, Stankovic ND, Bicker F, Meister J, Braun H, Awwad K, Baumgart J, Simon K, Thal SC, Patra C, Harter PN, Plate KH, Engel FB, Dimmeler S, Eble JA, Mittelbronn M, Schäfer MK, Jungblut B, Chavakis E, Fleming I & Schmidt MHH
EGFL7 ligates αvβ3 integrin to enhance vessel formation.
Blood, 2013 Apr 11, 121 (15) 3041-50

Respondek G, Roeber S, Kretzschmar H, Troakes C, Al-Sarraj S, Gelpi E, Gaig C, Chiu WZ, van Swieten JC, Oertel WH & Höglinger GU
Accuracy of the National Institute for Neurological Disorders and Stroke/Society for Progressive Supranuclear Palsy and neuroprotection and natural history in Parkinson plus syndromes criteria for the diagnosis of progressive supranuclear palsy.
Movement disorders : official journal of the Movement Disorder Society, 2013 Apr, 28 (4) 504-9

Johansson A, Faber F, Kniebühler G, Stepp H, Sroka R, Egensperger R, Beyer W & Kreth FW
Protoporphyrin IX fluorescence and photobleaching during interstitial photodynamic therapy of malignant gliomas for early treatment prognosis.
Lasers in surgery and medicine, 2013 Apr, 45 (4) 225-34

Mori K, Weng SM, Arzberger T, May S, Rentzsch K, Kremmer E, Schmid B, Kretzschmar HA, Cruts M, Van Broeckhoven C, Haass C & Edbauer D
The C9orf72 GGGGCC repeat is translated into aggregating dipeptide-repeat proteins in FTLD/ALS.
Science (New York, N.Y.), 2013 Mar 15, 339 (6125) 1335-8

Bonney S, Hughes K, Harter PN, Mittelbronn M, Walker L & Eckle T
Cardiac period 2 in myocardial ischemia: clinical implications of a light dependent protein.
The international journal of biochemistry & cell biology, 2013 Mar, 45 (3) 667-71

Mori K, Lammich S, Mackenzie IR, Forné I, Zilow S, Kretzschmar H, Edbauer D, Janssens J, Kleinberger G, Cruts M, Herms J, Neumann M, Van Broeckhoven C, Arzberger T & Haass C
hnRNP A3 binds to GGGGCC repeats and is a constituent of p62-positive/TDP43-negative inclusions in the hippocampus of patients with C9orf72 mutations.
Acta neuropathologica, 2013 Mar, 125 (3) 413-23

Enzmann G, Mysiorek C, Gorina R, Cheng YJ, Ghavampour S, Hannocks MJ, Prinz V, Dirnagl U, Endres M, Prinz M, Beschorner R, Harter PN, Mittelbronn M, Engelhardt B & Sorokin L
The neurovascular unit as a selective barrier to polymorphonuclear granulocyte (PMN) infiltration into the brain after ischemic injury.
Acta neuropathologica, 2013 Mar, 125 (3) 395-412

Birnbaum T, Langer S, Roeber S, von Baumgarten L & Straube A
Expression of B-cell activating factor, a proliferating inducing ligand and its receptors in primary central nervous system lymphoma.
Neurology international, 2013 Feb 11, 5 (1) e4

Kovacs GG, Rozemuller AJ, van Swieten JC, Gelpi E, Majtenyi K, Al-Sarraj S, Troakes C, Bódi I, King A, Hortobágyi T, Esiri MM, Ansorge O, Giaccone G, Ferrer I, Arzberger T, Bogdanovic N, Nilsson T, Leisser I, Alafuzoff I, Ironside JW, Kretzschmar H & Budka H
Neuropathology of the hippocampus in FTLD-Tau with Pick bodies: a study of the BrainNet Europe Consortium.
Neuropathology and applied neurobiology, 2013 Feb, 39 (2) 166-78

Honarnejad K, Jung CK, Lammich S, Arzberger T, Kretzschmar H & Herms J
Involvement of presenilin holoprotein upregulation in calcium dyshomeostasis of Alzheimer's disease.
Journal of cellular and molecular medicine, 2013 Feb, 17 (2) 293-302

Doberstein K, Steinmeyer N, Hartmetz AK, Eberhardt W, Mittelbronn M, Harter PN, Juengel E, Blaheta R, Pfeilschifter J & Gutwein P
MicroRNA-145 targets the metalloprotease ADAM17 and is suppressed in renal cell carcinoma patients.
Neoplasia (New York, N.Y.), 2013 Feb, 15 (2) 218-30

van der Zee J, Gijselinck I, Dillen L, Van Langenhove T, Theuns J, Engelborghs S, Philtjens S, Vandenbulcke M, Sleegers K, Sieben A, Bäumer V, Maes G, Corsmit E, Borroni B, Padovani A, Archetti S, Perneczky R, Diehl-Schmid J, de Mendonça A, Miltenberger-Miltenyi G, Pereira S, Pimentel J, Nacmias B, Bagnoli S, Sorbi S, Graff C, Chiang HH, Westerlund M, Sanchez-Valle R, Llado A, Gelpi E, Santana I, Almeida MR, Santiago B, Frisoni G, Zanetti O, Bonvicini C, Synofzik M, Maetzler W, Vom Hagen JM, Schöls L, Heneka MT, Jessen F, Matej R, Parobkova E, Kovacs GG, Ströbel T, Sarafov S, Tournev I, Jordanova A, Danek A, Arzberger T, Fabrizi GM, Testi S, Salmon E, Santens P, Martin JJ, Cras P, Vandenberghe R, De Deyn PP, Cruts M, Van Broeckhoven C, van der Zee J, Gijselinck I, Dillen L, Van Langenhove T, Theuns J, Philtjens S, Sleegers K, Bäumer V, Maes G, Corsmit E, Cruts M, Van Broeckhoven C, van der Zee J, Gijselinck I, Dillen L, Van Langenhove T, Philtjens S, Theuns J, Sleegers K, Bäumer V, Maes G, Cruts M, Van Broeckhoven C, Engelborghs S, De Deyn PP, Cras P, Engelborghs S, De Deyn PP, Vandenbulcke M, Vandenbulcke M, Borroni B, Padovani A, Archetti S, Perneczky R, Diehl-Schmid J, Synofzik M, Maetzler W, Müller Vom Hagen J, Schöls L, Synofzik M, Maetzler W, Müller Vom Hagen J, Schöls L, Heneka MT, Jessen F, Ramirez A, Kurzwelly D, Sachtleben C, Mairer W, de Mendonça A, Miltenberger-Miltenyi G, Pereira S, Firmo C, Pimentel J, Sanchez-Valle R, Llado A, Antonell A, Molinuevo J, Gelpi E, Graff C, Chiang HH, Westerlund M, Graff C, Kinhult Ståhlbom A, Thonberg H, Nennesmo I, Börjesson-Hanson A, Nacmias B, Bagnoli S, Sorbi S, Bessi V, Piaceri I, Santana I, Santiago B, Santana I, Helena Ribeiro M, Rosário Almeida M, Oliveira C, Massano J, Garret C, Pires P, Frisoni G, Zanetti O, Bonvicini C, Sarafov S, Tournev I, Jordanova A, Tournev I, Kovacs GG, Ströbel T, Heneka MT, Jessen F, Ramirez A, Kurzwelly D, Sachtleben C, Mairer W, Jessen F, Matej R, Parobkova E, Danel A, Arzberger T, Maria Fabrizi G, Testi S, Ferrari S, Cavallaro T, Salmon E, Santens P, Cras P & European Early-Onset Dementia Consortium
A pan-European study of the C9orf72 repeat associated with FTLD: geographic prevalence, genomic instability, and intermediate repeats.
Human mutation, 2013 Feb, 34 (2) 363-73

Stack MJ, Chaplin MJ, Davis LA, Everitt S, Simmons MM, Windl O, Hope J & Burke P
Four BSE cases with an L-BSE molecular profile in cattle from Great Britain.
The Veterinary record, 2013 Jan 19, 172 (3) 70

Okoroma EA, Purchase D, Garelick H, Morris R, Neale MH, Windl O & Abiola OO
Enzymatic formulation capable of degrading scrapie prion under mild digestion conditions.
PloS one, 2013, 8 (7) e68099

Ovsepian SV & Herms J
Cholinergic neurons-keeping check on amyloid β in the cerebral cortex.
Frontiers in cellular neuroscience, 2013, 7 252

Luger S, Harter PN, Mittelbronn M, Wagner M & Foerch C
Brain stem infarction associated with familial Mediterranean fever and central nervous system vasculitis.
Clinical and experimental rheumatology, 2013, 31 (3 Suppl 77) 93-5

2012

Jansen NL, Schwartz C, Graute V, Eigenbrod S, Lutz J, Egensperger R, Pöpperl G, Kretzschmar HA, Cumming P, Bartenstein P, Tonn JC, Kreth FW, la Fougère C & Thon N
Prediction of oligodendroglial histology and LOH 1p/19q using dynamic [(18)F]FET-PET imaging in intracranial WHO grade II and III gliomas.
Neuro-oncology, 2012 Dec, 14 (12) 1473-80

Bittner T, Burgold S, Dorostkar MM, Fuhrmann M, Wegenast-Braun BM, Schmidt B, Kretzschmar H & Herms J
Amyloid plaque formation precedes dendritic spine loss.
Acta neuropathologica, 2012 Dec, 124 (6) 797-807

Durrenberger PF, Fernando FS, Magliozzi R, Kashefi SN, Bonnert TP, Ferrer I, Seilhean D, Nait-Oumesmar B, Schmitt A, Gebicke-Haerter PJ, Falkai P, Grünblatt E, Palkovits M, Parchi P, Capellari S, Arzberger T, Kretzschmar H, Roncaroli F, Dexter DT & Reynolds R
Selection of novel reference genes for use in the human central nervous system: a BrainNet Europe Study.
Acta neuropathologica, 2012 Dec, 124 (6) 893-903

Schankin CJ, Reifferscheid AK, Krumbholz M, Linn J, Rachinger W, Langer S, Sostak P, Arzberger T, Kretzschmar H & Straube A
Headache in patients with pituitary adenoma: clinical and paraclinical findings.
Cephalalgia : an international journal of headache, 2012 Dec, 32 (16) 1198-207

Rüb U, Bürk K, Timmann D, den Dunnen W, Seidel K, Farrag K, Brunt E, Heinsen H, Egensperger R, Bornemann A, Schwarzacher S, Korf HW, Schöls L, Bohl J & Deller T
Spinocerebellar ataxia type 1 (SCA1): new pathoanatomical and clinico-pathological insights.
Neuropathology and applied neurobiology, 2012 Dec, 38 (7) 665-80

Bagetta V, Sgobio C, Pendolino V, Del Papa G, Tozzi A, Ghiglieri V, Giampà C, Zianni E, Gardoni F, Calabresi P & Picconi B
Rebalance of striatal NMDA/AMPA receptor ratio underlies the reduced emergence of dyskinesia during D2-like dopamine agonist treatment in experimental Parkinson's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012 Dec 05, 32 (49) 17921-31

Göbel W, Brucker D, Kienast Y, Johansson A, Kniebühler G, Rühm A, Eigenbrod S, Fischer S, Goetz M, Kreth FW, Ehrhardt A, Stepp H, Irion KM & Herms J
Optical needle endoscope for safe and precise stereotactically guided biopsy sampling in neurosurgery.
Optics express, 2012 Nov 19, 20 (24) 26117-26

Thorne L, Holder T, Ramsay A, Edwards J, Taema MM, Windl O, Maddison BC, Gough KC & Terry LA
In vitro amplification of ovine prions from scrapie-infected sheep from Great Britain reveals distinct patterns of propagation.
BMC veterinary research, 2012 Nov 15, 8 223

Schrötter A, Pfeiffer K, El Magraoui F, Platta HW, Erdmann R, Meyer HE, Egensperger R, Marcus K & Müller T
The amyloid precursor protein (APP) family members are key players in S-adenosylmethionine formation by MAT2A and modify BACE1 and PSEN1 gene expression-relevance for Alzheimer's disease.
Molecular & cellular proteomics : MCP, 2012 Nov, 11 (11) 1274-88

Alafuzoff I, Gelpi E, Al-Sarraj S, Arzberger T, Attems J, Bodi I, Bogdanovic N, Budka H, Bugiani O, Englund E, Ferrer I, Gentleman S, Giaccone G, Graeber MB, Hortobagyi T, Höftberger R, Ironside JW, Jellinger K, Kavantzas N, King A, Korkolopoulou P, Kovács GG, Meyronet D, Monoranu C, Parchi P, Patsouris E, Roggendorf W, Rozemuller A, Seilhean D, Streichenberger N, Thal DR, Wharton SB & Kretzschmar H
The need to unify neuropathological assessments of vascular alterations in the ageing brain: multicentre survey by the BrainNet Europe consortium.
Experimental gerontology, 2012 Nov, 47 (11) 825-33

Honarnejad K & Herms J
Presenilins: role in calcium homeostasis.
The international journal of biochemistry & cell biology, 2012 Nov, 44 (11) 1983-6

Boländer A, Kieser D, Voss C, Bauer S, Schön C, Burgold S, Bittner T, Hölzer J, Heyny-von Haußen R, Mall G, Goetschy V, Czech C, Knust H, Berger R, Herms J, Hilger I & Schmidt B
Bis(arylvinyl)pyrazines, -pyrimidines, and -pyridazines as imaging agents for tau fibrils and β-amyloid plaques in Alzheimer's disease models.
Journal of medicinal chemistry, 2012 Nov 08, 55 (21) 9170-80

Caruana M, Neuner J, Högen T, Schmidt F, Kamp F, Scerri C, Giese A & Vassallo N
Polyphenolic compounds are novel protective agents against lipid membrane damage by α-synuclein aggregates in vitro.
Biochimica et biophysica acta, 2012 Nov, 1818 (11) 2502-10

Brucker D & Herms J
A window into metastasis.
Science translational medicine, 2012 Oct 31, 4 (158) 158fs39

Parchi P, de Boni L, Saverioni D, Cohen ML, Ferrer I, Gambetti P, Gelpi E, Giaccone G, Hauw JJ, Höftberger R, Ironside JW, Jansen C, Kovacs GG, Rozemuller A, Seilhean D, Tagliavini F, Giese A & Kretzschmar HA
Consensus classification of human prion disease histotypes allows reliable identification of molecular subtypes: an inter-rater study among surveillance centres in Europe and USA.
Acta neuropathologica, 2012 Oct, 124 (4) 517-29

Schmitt A, Leonardi-Essmann F, Durrenberger PF, Wichert SP, Spanagel R, Arzberger T, Kretzschmar H, Zink M, Herrera-Marschitz M, Reynolds R, Rossner MJ, Falkai P & Gebicke-Haerter PJ
Structural synaptic elements are differentially regulated in superior temporal cortex of schizophrenia patients.
European archives of psychiatry and clinical neuroscience, 2012 Oct, 262 (7) 565-77

Dorostkar MM & Herms J
Arc illuminates Alzheimer's pathophysiology.
Nature neuroscience, 2012 Oct, 15 (10) 1323-5

Nübling G, Levin J, Bader B, Israel L, Bötzel K, Lorenzl S & Giese A
Limited cleavage of tau with matrix-metalloproteinase MMP-9, but not MMP-3, enhances tau oligomer formation.
Experimental neurology, 2012 Oct, 237 (2) 470-6

Eisele S, Krumbholz M, Fischer MT, Mohan H, Junker A, Arzberger T, Hohlfeld R, Bradl M, Lassmann H & Meinl E
Prospects of transcript profiling for mRNAs and MicroRNAs using formalin-fixed and paraffin-embedded dissected autoptic multiple sclerosis lesions.
Brain pathology (Zurich, Switzerland), 2012 Sep, 22 (5) 607-18

Gardoni F, Sgobio C, Pendolino V, Calabresi P, Di Luca M & Picconi B
Targeting NR2A-containing NMDA receptors reduces L-DOPA-induced dyskinesias.
Neurobiology of aging, 2012 Sep, 33 (9) 2138-44

Kögel D, Concannon CG, Müller T, König H, Bonner C, Poeschel S, Chang S, Egensperger R & Prehn JH
The APP intracellular domain (AICD) potentiates ER stress-induced apoptosis.
Neurobiology of aging, 2012 Sep, 33 (9) 2200-9

Fiorino F, Eiden M, Giese A, Severino B, Esposito A, Groschup MH, Perissutti E, Magli E, Incisivo GM, Ciano A, Frecentese F, Kretzschmar HA, Wagner J, Santagada V & Caliendo G
Synthesis of benzamide derivatives and their evaluation as antiprion agents.
Bioorganic & medicinal chemistry, 2012 Aug 15, 20 (16) 5001-11

Ottis P, Koppe K, Onisko B, Dynin I, Arzberger T, Kretzschmar H, Requena JR, Silva CJ, Huston JP & Korth C
Human and rat brain lipofuscin proteome.
Proteomics, 2012 Aug, 12 (15-16) 2445-54

Sundal C, Van Gerpen JA, Nicholson AM, Wider C, Shuster EA, Aasly J, Spina S, Ghetti B, Roeber S, Garbern J, Borjesson-Hanson A, Tselis A, Swerdlow RH, Miller BB, Fujioka S, Heckman MG, Uitti RJ, Josephs KA, Baker M, Andersen O, Rademakers R, Dickson DW, Broderick D & Wszolek ZK
MRI characteristics and scoring in HDLS due to CSF1R gene mutations.
Neurology, 2012 Aug 07, 79 (6) 566-74

Ghiglieri V, Pendolino V, Sgobio C, Bagetta V, Picconi B & Calabresi P
Θ-burst stimulation and striatal plasticity in experimental parkinsonism.
Experimental neurology, 2012 Aug, 236 (2) 395-8

Nübling G, Bader B, Levin J, Hildebrandt J, Kretzschmar H & Giese A
Synergistic influence of phosphorylation and metal ions on tau oligomer formation and coaggregation with α-synuclein at the single molecule level.
Molecular neurodegeneration, 2012 Jul 23, 7 35

Höring E, Harter PN, Seznec J, Schittenhelm J, Bühring HJ, Bhattacharyya S, von Hattingen E, Zachskorn C, Mittelbronn M & Naumann U
The "go or grow" potential of gliomas is linked to the neuropeptide processing enzyme carboxypeptidase E and mediated by metabolic stress.
Acta neuropathologica, 2012 Jul, 124 (1) 83-97

Klinger F, Geier P, Dorostkar MM, Chandaka GK, Yousuf A, Salzer I, Kubista H & Boehm S
Concomitant facilitation of GABAA receptors and KV7 channels by the non-opioid analgesic flupirtine.
British journal of pharmacology, 2012 Jul, 166 (5) 1631-42

Lin X, Parisiadou L, Sgobio C, Liu G, Yu J, Sun L, Shim H, Gu XL, Luo J, Long CX, Ding J, Mateo Y, Sullivan PH, Wu LG, Goldstein DS, Lovinger D & Cai H
Conditional expression of Parkinson's disease-related mutant α-synuclein in the midbrain dopaminergic neurons causes progressive neurodegeneration and degradation of transcription factor nuclear receptor related 1.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012 Jul 04, 32 (27) 9248-64

Tennstaedt A, Pöpsel S, Truebestein L, Hauske P, Brockmann A, Schmidt N, Irle I, Sacca B, Niemeyer CM, Brandt R, Ksiezak-Reding H, Tirniceriu AL, Egensperger R, Baldi A, Dehmelt L, Kaiser M, Huber R, Clausen T & Ehrmann M
Human high temperature requirement serine protease A1 (HTRA1) degrades tau protein aggregates.
The Journal of biological chemistry, 2012 Jun 15, 287 (25) 20931-41

Lin MT, Cantuti-Castelvetri I, Zheng K, Jackson KE, Tan YB, Arzberger T, Lees AJ, Betensky RA, Beal MF & Simon DK
Somatic mitochondrial DNA mutations in early Parkinson and incidental Lewy body disease.
Annals of neurology, 2012 Jun, 71 (6) 850-4

Costa C, Sgobio C, Siliquini S, Tozzi A, Tantucci M, Ghiglieri V, Di Filippo M, Pendolino V, de Iure A, Marti M, Morari M, Spillantini MG, Latagliata EC, Pascucci T, Puglisi-Allegra S, Gardoni F, Di Luca M, Picconi B & Calabresi P
Mechanisms underlying the impairment of hippocampal long-term potentiation and memory in experimental Parkinson's disease.
Brain : a journal of neurology, 2012 Jun, 135 (Pt 6) 1884-99

Koeppen M, Harter PN, Bonney S, Bonney M, Reithel S, Zachskorn C, Mittelbronn M & Eckle T
Adora2b signaling on bone marrow derived cells dampens myocardial ischemia-reperfusion injury.
Anesthesiology, 2012 Jun, 116 (6) 1245-57

Frick A, Grammel D, Schmidt F, Pöschl J, Priller M, Pagella P, von Bueren AO, Peraud A, Tonn JC, Herms J, Rutkowski S, Kretzschmar HA & Schüller U
Proper cerebellar development requires expression of β1-integrin in Bergmann glia, but not in granule neurons.
Glia, 2012 May, 60 (5) 820-32

Eigenbrod S, Thon N, Jansen N, Janssen H, Mielke J, Ruiter M, la Fougère C, Peraud A, Egensperger R & Kretzschmar H
Intramedullary pilomyxoid astrocytoma with intracerebral metastasis exhibiting oligoden-droglioma-like features.
Rare tumors, 2012 Apr 12, 4 (2) e30

Jung CK & Herms J
Role of APP for dendritic spine formation and stability.
Experimental brain research, 2012 Apr, 217 (3-4) 463-70

Martins-de-Souza D, Guest PC, Mann DM, Roeber S, Rahmoune H, Bauder C, Kretzschmar H, Volk B, Baborie A & Bahn S
Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration.
Journal of proteome research, 2012 Apr 06, 11 (4) 2533-43

Högen T, Levin J, Schmidt F, Caruana M, Vassallo N, Kretzschmar H, Bötzel K, Kamp F & Giese A
Two different binding modes of α-synuclein to lipid vesicles depending on its aggregation state.
Biophysical journal, 2012 Apr 04, 102 (7) 1646-55

Strübing F, Herrojo Ruiz M, Jabusch HC & Altenmüller E
Error monitoring is altered in musician's dystonia: evidence from ERP-based studies.
Annals of the New York Academy of Sciences, 2012 Apr, 1252 192-9

Sundal C, Lash J, Aasly J, Øygarden S, Roeber S, Kretzschman H, Garbern JY, Tselis A, Rademakers R, Dickson DW, Broderick D & Wszolek ZK
Hereditary diffuse leukoencephalopathy with axonal spheroids (HDLS): a misdiagnosed disease entity.
Journal of the neurological sciences, 2012 Mar 15, 314 (1-2) 130-7

Hokkanen S, Feldmann HM, Ding H, Jung CK, Bojarski L, Renner-Müller I, Schüller U, Kretzschmar H, Wolf E & Herms J
Lack of Pur-alpha alters postnatal brain development and causes megalencephaly.
Human molecular genetics, 2012 Feb 01, 21 (3) 473-84

Martins-de-Souza D, Guest PC, Guest FL, Bauder C, Rahmoune H, Pietsch S, Roeber S, Kretzschmar H, Mann D, Baborie A & Bahn S
Characterization of the human primary visual cortex and cerebellum proteomes using shotgun mass spectrometry-data-independent analyses.
Proteomics, 2012 Feb, 12 (3) 500-4

Willhauck MJ, Pöpperl G, Rachinger W, Giese A, Auernhammer CJ & Spitzweg C
An unusual case of ectopic ACTH syndrome.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2012 Feb, 120 (2) 63-7

Trabalza A, Colazingari S, Sgobio C & Bevilacqua A
Contextual learning increases dendrite complexity and EphrinB2 levels in hippocampal mouse neurons.
Behavioural brain research, 2012 Feb 01, 227 (1) 175-83

Windl O & Dawson M
Animal prion diseases.
Sub-cellular biochemistry, 2012, 65 497-516

Schön C, Hoffmann NA, Ochs SM, Burgold S, Filser S, Steinbach S, Seeliger MW, Arzberger T, Goedert M, Kretzschmar HA, Schmidt B & Herms J
Long-term in vivo imaging of fibrillar tau in the retina of P301S transgenic mice.
PloS one, 2012, 7 (12) e53547

Schmidt C, Haïk S, Satoh K, Rábano A, Martinez-Martin P, Roeber S, Brandel JP, Calero-Lara M, de Pedro-Cuesta J, Laplanche JL, Hauw JJ, Kretzschmar H & Zerr I
Rapidly progressive Alzheimer's disease: a multicenter update.
Journal of Alzheimer's disease : JAD, 2012, 30 (4) 751-6

Podlech O, Harter PN, Mittelbronn M, Pöschel S & Naumann U
Fermented mistletoe extract as a multimodal antitumoral agent in gliomas.
Evidence-based complementary and alternative medicine : eCAM, 2012, 2012 501796

Herold T, Seiler T, Egensperger R, Trumm C, Bergmann M, Franke D, Mumm FF, Schinwald N, Buske C & Dreyling M
Progressive multifocal leukoencephalopathy after treatment with rituximab, fludarabine and cyclophosphamide in a patient with chronic lymphocytic leukemia.
Leukemia & lymphoma, 2012 Jan, 53 (1) 169-72

2011

Rademakers R, Baker M, Nicholson AM, Rutherford NJ, Finch N, Soto-Ortolaza A, Lash J, Wider C, Wojtas A, DeJesus-Hernandez M, Adamson J, Kouri N, Sundal C, Shuster EA, Aasly J, MacKenzie J, Roeber S, Kretzschmar HA, Boeve BF, Knopman DS, Petersen RC, Cairns NJ, Ghetti B, Spina S, Garbern J, Tselis AC, Uitti R, Das P, Van Gerpen JA, Meschia JF, Levy S, Broderick DF, Graff-Radford N, Ross OA, Miller BB, Swerdlow RH, Dickson DW & Wszolek ZK
Mutations in the colony stimulating factor 1 receptor (CSF1R) gene cause hereditary diffuse leukoencephalopathy with spheroids.
Nature genetics, 2011 Dec 25, 44 (2) 200-5

de Boni L, Tierling S, Roeber S, Walter J, Giese A & Kretzschmar HA
Next-generation sequencing reveals regional differences of the α-synuclein methylation state independent of Lewy body disease.
Neuromolecular medicine, 2011 Dec, 13 (4) 310-20

Jung CK, Fuhrmann M, Honarnejad K, Van Leuven F & Herms J
Role of presenilin 1 in structural plasticity of cortical dendritic spines in vivo.
Journal of neurochemistry, 2011 Dec, 119 (5) 1064-73

Pöschl J, Lorenz A, Hartmann W, von Bueren AO, Kool M, Li S, Peraud A, Tonn JC, Herms J, Xiang M, Rutkowski S, Kretzschmar HA & Schüller U
Expression of BARHL1 in medulloblastoma is associated with prolonged survival in mice and humans.
Oncogene, 2011 Nov 24, 30 (47) 4721-30

Oberländer U, Pletinckx K, Döhler A, Müller N, Lutz MB, Arzberger T, Riederer P, Gerlach M, Koutsilieri E & Scheller C
Neuromelanin is an immune stimulator for dendritic cells in vitro.
BMC neuroscience, 2011 Nov 15, 12 116

Scholz A, Lang V, Henschler R, Czabanka M, Vajkoczy P, Chavakis E, Drynski J, Harter PN, Mittelbronn M, Dumont DJ, Plate KH & Reiss Y
Angiopoietin-2 promotes myeloid cell infiltration in a β₂-integrin-dependent manner.
Blood, 2011 Nov 03, 118 (18) 5050-9

Eigenbrod S, Roeber S, Thon N, Giese A, Krieger A, Grasbon-Frodl E, Egensperger R, Tonn JC, Kreth FW & Kretzschmar HA
α-Internexin in the diagnosis of oligodendroglial tumors and association with 1p/19q status.
Journal of neuropathology and experimental neurology, 2011 Nov, 70 (11) 970-8

Goldmann W, Ryan K, Stewart P, Parnham D, Xicohtencatl R, Fernandez N, Saunders G, Windl O, González L, Bossers A & Foster J
Caprine prion gene polymorphisms are associated with decreased incidence of classical scrapie in goat herds in the United Kingdom.
Veterinary research, 2011 Oct 31, 42 (1) 110

Reichert S, Rödel C, Mirsch J, Harter PN, Tomicic MT, Mittelbronn M, Kaina B & Rödel F
Survivin inhibition and DNA double-strand break repair: a molecular mechanism to overcome radioresistance in glioblastoma.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2011 Oct, 101 (1) 51-8

Leidel F, Eiden M, Geissen M, Kretzschmar HA, Giese A, Hirschberger T, Tavan P, Schätzl HM & Groschup MH
Diphenylpyrazole-derived compounds increase survival time of mice after prion infection.
Antimicrobial agents and chemotherapy, 2011 Oct, 55 (10) 4774-81

von Baumgarten L, Brucker D, Tirniceru A, Kienast Y, Grau S, Burgold S, Herms J & Winkler F
Bevacizumab has differential and dose-dependent effects on glioma blood vessels and tumor cells.
Clinical cancer research : an official journal of the American Association for Cancer Research, 2011 Oct 01, 17 (19) 6192-205

Geissen M, Leidel F, Eiden M, Hirschberger T, Fast C, Bertsch U, Tavan P, Giese A, Kretzschmar H, Schatzl HM & Groschup MH
From high-throughput cell culture screening to mouse model: identification of new inhibitor classes against prion disease.
ChemMedChem, 2011 Oct 04, 6 (10) 1928-37

Hartig MB, Iuso A, Haack T, Kmiec T, Jurkiewicz E, Heim K, Roeber S, Tarabin V, Dusi S, Krajewska-Walasek M, Jozwiak S, Hempel M, Winkelmann J, Elstner M, Oexle K, Klopstock T, Mueller-Felber W, Gasser T, Trenkwalder C, Tiranti V, Kretzschmar H, Schmitz G, Strom TM, Meitinger T & Prokisch H
Absence of an orphan mitochondrial protein, c19orf12, causes a distinct clinical subtype of neurodegeneration with brain iron accumulation.
American journal of human genetics, 2011 Oct 07, 89 (4) 543-50

Mittelbronn M, Platten M, Zeiner P, Dombrowski Y, Frank B, Zachskorn C, Harter PN, Weller M & Wischhusen J
Macrophage migration inhibitory factor (MIF) expression in human malignant gliomas contributes to immune escape and tumour progression.
Acta neuropathologica, 2011 Sep, 122 (3) 353-65

Neumann M, Bentmann E, Dormann D, Jawaid A, DeJesus-Hernandez M, Ansorge O, Roeber S, Kretzschmar HA, Munoz DG, Kusaka H, Yokota O, Ang LC, Bilbao J, Rademakers R, Haass C & Mackenzie IR
FET proteins TAF15 and EWS are selective markers that distinguish FTLD with FUS pathology from amyotrophic lateral sclerosis with FUS mutations.
Brain : a journal of neurology, 2011 Sep, 134 (Pt 9) 2595-609

Kummer MP, Hermes M, Delekarte A, Hammerschmidt T, Kumar S, Terwel D, Walter J, Pape HC, König S, Roeber S, Jessen F, Klockgether T, Korte M & Heneka MT
Nitration of tyrosine 10 critically enhances amyloid β aggregation and plaque formation.
Neuron, 2011 Sep 08, 71 (5) 833-44

Bagetta V, Picconi B, Marinucci S, Sgobio C, Pendolino V, Ghiglieri V, Fusco FR, Giampà C & Calabresi P
Dopamine-dependent long-term depression is expressed in striatal spiny neurons of both direct and indirect pathways: implications for Parkinson's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011 Aug 31, 31 (35) 12513-22

Scheibe S, Dorostkar MM, Seebacher C, Uhl R, Lison F & Herms J
4D in in vivo 2-photon laser scanning fluorescence microscopy with sample motion in 6 degrees of freedom.
Journal of neuroscience methods, 2011 Aug 30, 200 (1) 47-53

Duering M, Karpinska A, Rosner S, Hopfner F, Zechmeister M, Peters N, Kremmer E, Haffner C, Giese A, Dichgans M & Opherk C
Co-aggregate formation of CADASIL-mutant NOTCH3: a single-particle analysis.
Human molecular genetics, 2011 Aug 15, 20 (16) 3256-65

Müller T, Loosse C, Schrötter A, Schnabel A, Helling S, Egensperger R & Marcus K
The AICD interacting protein DAB1 is up-regulated in Alzheimer frontal cortex brain samples and causes deregulation of proteins involved in gene expression changes.
Current Alzheimer research, 2011 Aug, 8 (5) 573-82

Berger A, Reitter A, Harter PN, Buxmann H, Allwinn R, Louwen F & Doerr HW
Problems and challenges in the diagnosis of vertical infection with human cytomegalovirus (CMV): lessons from two accidental cases.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2011 Aug, 51 (4) 285-8

Maurer GD, Brucker DP, Bähr O, Harter PN, Hattingen E, Walenta S, Mueller-Klieser W, Steinbach JP & Rieger J
Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogenic diet as experimental glioma therapy.
BMC cancer, 2011 Jul 26, 11 315

Bader B, Nübling G, Mehle A, Nobile S, Kretzschmar H & Giese A
Single particle analysis of tau oligomer formation induced by metal ions and organic solvents.
Biochemical and biophysical research communications, 2011 Jul 22, 411 (1) 190-6

Schuss P, Ulrich CT, Harter PN, Tews DS, Seifert V & Franz K
Gliosarcoma with bone infiltration and extracranial growth: case report and review of literature.
Journal of neuro-oncology, 2011 Jul, 103 (3) 765-70

Ghiglieri V, Sgobio C, Costa C, Picconi B & Calabresi P
Striatum-hippocampus balance: from physiological behavior to interneuronal pathology.
Progress in neurobiology, 2011 Jul, 94 (2) 102-14

Roeber , Höglinger GU, Melhem NM, Dickson DW, Sleiman PM, Wang LS, Klei L, Rademakers R, de Silva R, Litvan I, Riley DE, van Swieten JC, Heutink P, Wszolek ZK, Uitti RJ, Vandrovcova J, Hurtig HI, Gross RG, Maetzler W, Goldwurm S, Tolosa E, Borroni B, Pastor P, PSP Genetics Study Group, Cantwell LB, Han MR, Dillman A, van der Brug MP, Gibbs JR, Cookson MR, Hernandez DG, Singleton AB, Farrer MJ, Yu CE, Golbe LI, Revesz T, Hardy J, Lees AJ, Devlin B, Hakonarson H, Müller U & Schellenberg GD
Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy.
Nature genetics, 2011 Jun 19, 43 (7) 699-705

Hüls S, Högen T, Vassallo N, Danzer KM, Hengerer B, Giese A & Herms J
AMPA-receptor-mediated excitatory synaptic transmission is enhanced by iron-induced α-synuclein oligomers.
Journal of neurochemistry, 2011 Jun, 117 (5) 868-78

Mollenhauer B, Esselmann H, Roeber S, Schulz-Schaeffer WJ, Trenkwalder C, Bibl M, Steinacker P, Kretzschmar HA, Wiltfang J & Otto M
Different CSF β-amyloid processing in Alzheimer's and Creutzfeldt-Jakob disease.
Journal of neural transmission (Vienna, Austria : 1996), 2011 May, 118 (5) 691-7

Caruana M, Högen T, Levin J, Hillmer A, Giese A & Vassallo N
Inhibition and disaggregation of α-synuclein oligomers by natural polyphenolic compounds.
FEBS letters, 2011 Apr 20, 585 (8) 1113-20

Schittenhelm J, Simon P, Harter PN, Zachskorn C, Schlaszus H, Röttger F, Winkels M, Weller M, Meyermann R & Mittelbronn M
CD133 expression is associated with small round blue cell tumour morphology in human central nervous system neoplasms.
Histopathology, 2011 Apr, 58 (5) 739-49

Schmitt A, Leonardi-Essmann F, Durrenberger PF, Parlapani E, Schneider-Axmann T, Spanagel R, Arzberger T, Kretzschmar H, Herrera-Marschitz M, Gruber O, Reynolds R, Falkai P & Gebicke-Haerter PJ
Regulation of immune-modulatory genes in left superior temporal cortex of schizophrenia patients: a genome-wide microarray study.
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2011 Apr, 12 (3) 201-15

Spalloni A, Origlia N, Sgobio C, Trabalza A, Nutini M, Berretta N, Bernardi G, Domenici L, Ammassari-Teule M & Longone P
Postsynaptic alteration of NR2A subunit and defective autophosphorylation of alphaCaMKII at threonine-286 contribute to abnormal plasticity and morphology of upper motor neurons in presymptomatic SOD1G93A mice, a murine model for amyotrophic lateral sclerosis.
Cerebral cortex (New York, N.Y. : 1991), 2011 Apr, 21 (4) 796-805

Giaccone G, Arzberger T, Alafuzoff I, Al-Sarraj S, Budka H, Duyckaerts C, Falkai P, Ferrer I, Ironside JW, Kovács GG, Meyronet D, Parchi P, Patsouris E, Revesz T, Riederer P, Rozemuller A, Schmitt A, Winblad B, Kretzschmar H & BrainNet Europe consortium
New lexicon and criteria for the diagnosis of Alzheimer's disease.
The Lancet. Neurology, 2011 Apr, 10 (4) 298-9; author reply 300-1

D'Amato FR, Zanettini C, Sgobio C, Sarli C, Carone V, Moles A & Ammassari-Teule M
Intensification of maternal care by double-mothering boosts cognitive function and hippocampal morphology in the adult offspring.
Hippocampus, 2011 Mar, 21 (3) 298-308

Kunz M, Thon N, Eigenbrod S, Hartmann C, Egensperger R, Herms J, Geisler J, la Fougere C, Lutz J, Linn J, Kreth S, von Deimling A, Tonn JC, Kretzschmar HA, Pöpperl G & Kreth FW
Hot spots in dynamic (18)FET-PET delineate malignant tumor parts within suspected WHO grade II gliomas.
Neuro-oncology, 2011 Mar, 13 (3) 307-16

Burgold S, Bittner T, Dorostkar MM, Kieser D, Fuhrmann M, Mitteregger G, Kretzschmar H, Schmidt B & Herms J
In vivo multiphoton imaging reveals gradual growth of newborn amyloid plaques over weeks.
Acta neuropathologica, 2011 Mar, 121 (3) 327-35

Eigenbrod S, Frick P, Giese A, Schelzke G, Zerr I & Kretzschmar HA
Comprehensive neuropathologic analysis of genetic prion disease associated with the E196K mutation in PRNP reveals phenotypic heterogeneity.
Journal of neuropathology and experimental neurology, 2011 Mar, 70 (3) 192-200

Kreth S, Thon N, Eigenbrod S, Lutz J, Ledderose C, Egensperger R, Tonn JC, Kretzschmar HA, Hinske LC & Kreth FW
O-methylguanine-DNA methyltransferase (MGMT) mRNA expression predicts outcome in malignant glioma independent of MGMT promoter methylation.
PloS one, 2011 Feb 18, 6 (2) e17156

Capper D, Reuss D, Schittenhelm J, Hartmann C, Bremer J, Sahm F, Harter PN, Jeibmann A & von Deimling A
Mutation-specific IDH1 antibody differentiates oligodendrogliomas and oligoastrocytomas from other brain tumors with oligodendroglioma-like morphology.
Acta neuropathologica, 2011 Feb, 121 (2) 241-52

Mackenzie IR, Munoz DG, Kusaka H, Yokota O, Ishihara K, Roeber S, Kretzschmar HA, Cairns NJ & Neumann M
Distinct pathological subtypes of FTLD-FUS.
Acta neuropathologica, 2011 Feb, 121 (2) 207-18

Papasavva-Stylianou P, Windl O, Saunders G, Mavrikiou P, Toumazos P & Kakoyiannis C
PrP gene polymorphisms in Cyprus goats and their association with resistance or susceptibility to natural scrapie.
Veterinary journal (London, England : 1997), 2011 Feb, 187 (2) 245-50

Picconi B, Bagetta V, Ghiglieri V, Paillè V, Di Filippo M, Pendolino V, Tozzi A, Giampà C, Fusco FR, Sgobio C & Calabresi P
Inhibition of phosphodiesterases rescues striatal long-term depression and reduces levodopa-induced dyskinesia.
Brain : a journal of neurology, 2011 Feb, 134 (Pt 2) 375-87

Capell A, Liebscher S, Fellerer K, Brouwers N, Willem M, Lammich S, Gijselinck I, Bittner T, Carlson AM, Sasse F, Kunze B, Steinmetz H, Jansen R, Dormann D, Sleegers K, Cruts M, Herms J, Van Broeckhoven C & Haass C
Rescue of progranulin deficiency associated with frontotemporal lobar degeneration by alkalizing reagents and inhibition of vacuolar ATPase.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011 Feb 02, 31 (5) 1885-94

Demel C, Hoegen T, Giese A, Angele B, Pfister HW, Koedel U & Klein M
Reduced spiral ganglion neuronal loss by adjunctive neurotrophin-3 in experimental pneumococcal meningitis.
Journal of neuroinflammation, 2011 Jan 24, 8 (1) 7

Levin J, Högen T, Hillmer AS, Bader B, Schmidt F, Kamp F, Kretzschmar HA, Bötzel K & Giese A
Generation of ferric iron links oxidative stress to α-synuclein oligomer formation.
Journal of Parkinson's disease, 2011, 1 (2) 205-16

Gauci AJ, Caruana M, Giese A, Scerri C & Vassallo N
Identification of polyphenolic compounds and black tea extract as potent inhibitors of lipid membrane destabilization by Aβ₄₂ aggregates.
Journal of Alzheimer's disease : JAD, 2011, 27 (4) 767-79

Parchi P, Strammiello R, Giese A & Kretzschmar H
Phenotypic variability of sporadic human prion disease and its molecular basis: past, present, and future.
Acta neuropathologica, 2011 Jan, 121 (1) 91-112

2010

Tang Y, Xiang W, Terry L, Kretzschmar HA & Windl O
Transcriptional analysis implicates endoplasmic reticulum stress in bovine spongiform encephalopathy.
PloS one, 2010 Dec 03, 5 (12) e14207

Harter PN, Bunz B, Dietz K, Hoffmann K, Meyermann R & Mittelbronn M
Spatio-temporal deleted in colorectal cancer (DCC) and netrin-1 expression in human foetal brain development.
Neuropathology and applied neurobiology, 2010 Dec, 36 (7) 623-35

Ghiglieri V, Pendolino V, Bagetta V, Sgobio C, Calabresi P & Picconi B
mTOR inhibitor rapamycin suppresses striatal post-ischemic LTP.
Experimental neurology, 2010 Dec, 226 (2) 328-31

Bittner T, Fuhrmann M, Burgold S, Ochs SM, Hoffmann N, Mitteregger G, Kretzschmar H, LaFerla FM & Herms J
Multiple events lead to dendritic spine loss in triple transgenic Alzheimer's disease mice.
PloS one, 2010 Nov 16, 5 (11) e15477

Berg D, Godau J, Riederer P, Gerlach M & Arzberger T
Microglia activation is related to substantia nigra echogenicity.
Journal of neural transmission (Vienna, Austria : 1996), 2010 Nov, 117 (11) 1287-92

Paillé V, Picconi B, Bagetta V, Ghiglieri V, Sgobio C, Di Filippo M, Viscomi MT, Giampà C, Fusco FR, Gardoni F, Bernardi G, Greengard P, Di Luca M & Calabresi P
Distinct levels of dopamine denervation differentially alter striatal synaptic plasticity and NMDA receptor subunit composition.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010 Oct 20, 30 (42) 14182-93

Kamp F, Exner N, Lutz AK, Wender N, Hegermann J, Brunner B, Nuscher B, Bartels T, Giese A, Beyer K, Eimer S, Winklhofer KF & Haass C
Inhibition of mitochondrial fusion by α-synuclein is rescued by PINK1, Parkin and DJ-1.
The EMBO journal, 2010 Oct 20, 29 (20) 3571-89

Parchi P, Cescatti M, Notari S, Schulz-Schaeffer WJ, Capellari S, Giese A, Zou WQ, Kretzschmar H, Ghetti B & Brown P
Agent strain variation in human prion disease: insights from a molecular and pathological review of the National Institutes of Health series of experimentally transmitted disease.
Brain : a journal of neurology, 2010 Oct, 133 (10) 3030-42

El Hindy N, Adamzik M, Lambertz N, Bachmann HS, Worm K, Egensperger R, Frey UH, Asgari S, Sure U, Siffert W & Sandalcioglu IE
Association of the GNB3 825T-allele with better survival in patients with glioblastoma multiforme.
Journal of cancer research and clinical oncology, 2010 Sep, 136 (9) 1423-9

Yoon MS, Bechmann L, Obermann M, Yepnjouo O, Egensperger R, Gerken G, Katsarava Z, Thomale J & Holtmann G
Recombinant human erythropoietin counteracts cisplatin-induced visceral hyperalgesia.
Neuroscience bulletin, 2010 Aug, 26 (4) 282-8

Sostak P, Padovan CS, Eigenbrod S, Roeber S, Segerer S, Schankin C, Siegert S, Saam T, Theil D, Kolb HJ, Kretzschmar H & Straube A
Cerebral angiitis in four patients with chronic GVHD.
Bone marrow transplantation, 2010 Jul, 45 (7) 1181-8

Mitterreiter S, Page RM, Kamp F, Hopson J, Winkler E, Ha HR, Hamid R, Herms J, Mayer TU, Nelson DJ, Steiner H, Stahl T, Zeitschel U, Rossner S, Haass C & Lichtenthaler SF
Bepridil and amiodarone simultaneously target the Alzheimer's disease beta- and gamma-secretase via distinct mechanisms.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010 Jun 30, 30 (26) 8974-83

Kreth S, Heyn J, Grau S, Kretzschmar HA, Egensperger R & Kreth FW
Identification of valid endogenous control genes for determining gene expression in human glioma.
Neuro-oncology, 2010 Jun, 12 (6) 570-9

Ghiglieri V, Sgobio C, Patassini S, Bagetta V, Fejtova A, Giampà C, Marinucci S, Heyden A, Gundelfinger ED, Fusco FR, Calabresi P & Picconi B
TrkB/BDNF-dependent striatal plasticity and behavior in a genetic model of epilepsy: modulation by valproic acid.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010 Jun, 35 (7) 1531-40

Grabellus F, Konik MJ, Worm K, Sheu SY, van de Nes JA, Bauer S, Paulus W, Egensperger R & Schmid KW
MET overexpressing chordomas frequently exhibit polysomy of chromosome 7 but no MET activation through sarcoma-specific gene fusions.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2010 Jun, 31 (3) 157-63

Dorostkar MM, Dreosti E, Odermatt B & Lagnado L
Computational processing of optical measurements of neuronal and synaptic activity in networks.
Journal of neuroscience methods, 2010 Apr 30, 188 (1) 141-50

Zausinger S, Schoeller K, Arzberger T & Muacevic A
Combined surgical and radiosurgical treatment of symptomatic aggressive vertebral osteomyelitis.
Minimally invasive neurosurgery : MIN, 2010 Apr, 53 (2) 80-2

Bagetta V, Ghiglieri V, Sgobio C, Calabresi P & Picconi B
Synaptic dysfunction in Parkinson's disease.
Biochemical Society transactions, 2010 Apr, 38 (2) 493-7

Levin J, Bulst S, Thirion C, Schmidt F, Bötzel K, Krause S, Pertl C, Kretzschmar H, Walter MC, Giese A & Lochmüller H
Divergent molecular effects of desmin mutations on protein assembly in myofibrillar myopathy.
Journal of neuropathology and experimental neurology, 2010 Apr, 69 (4) 415-24

Fuhrmann M, Bittner T, Jung CK, Burgold S, Page RM, Mitteregger G, Haass C, LaFerla FM, Kretzschmar H & Herms J
Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease.
Nature neuroscience, 2010 Apr, 13 (4) 411-3

Sgobio C, Ghiglieri V, Costa C, Bagetta V, Siliquini S, Barone I, Di Filippo M, Gardoni F, Gundelfinger ED, Di Luca M, Picconi B & Calabresi P
Hippocampal synaptic plasticity, memory, and epilepsy: effects of long-term valproic acid treatment.
Biological psychiatry, 2010 Mar 15, 67 (6) 567-74

Bacher M, Deuster O, Aljabari B, Egensperger R, Neff F, Jessen F, Popp J, Noelker C, Reese JP, Al-Abed Y & Dodel R
The role of macrophage migration inhibitory factor in Alzheimer's disease.
Molecular medicine (Cambridge, Mass.), 2010 Mar, 16 (3-4) 116-21

Albayrak O, Tirniceriu A, Riemenschneider M, Kurz A, Scherag A & Egensperger R
The cathepsin D (224C/T) polymorphism confers an increased risk to develop Alzheimer's disease in men.
The journals of gerontology. Series A, Biological sciences and medical sciences, 2010 Mar, 65 (3) 219-24

Neale MH, Mountjoy SJ, Edwards JC, Vilette D, Laude H, Windl O & Saunders GC
Infection of cell lines with experimental and natural ovine scrapie agents.
Journal of virology, 2010 Mar, 84 (5) 2444-52

Dützmann S, Gessler F, Harter PN, Gerlach R, Mittelbronn M, Seifert V & Kögel D
The pro-migratory and pro-invasive role of the procoagulant tissue factor in malignant gliomas.
Cell adhesion & migration, 2010, 4 (4) 515-22

Provansal M, Roche S, Pastore M, Casanova D, Belondrade M, Alais S, Leblanc P, Windl O & Lehmann S
Proteomic consequences of expression and pathological conversion of the prion protein in inducible neuroblastoma N2a cells.
Prion, 2010, 4 (4) 292-301

Johansson A, Palte G, Schnell O, Tonn JC, Herms J & Stepp H
5-Aminolevulinic acid-induced protoporphyrin IX levels in tissue of human malignant brain tumors.
Photochemistry and photobiology, 2010, 86 (6) 1373-8

Levin J, Bötzel K, Giese A, Vogeser M & Lorenzl S
Elevated levels of methylmalonate and homocysteine in Parkinson's disease, progressive supranuclear palsy and amyotrophic lateral sclerosis.
Dementia and geriatric cognitive disorders, 2010, 29 (6) 553-9

Schmidt C, Redyk K, Meissner B, Krack L, von Ahsen N, Roeber S, Kretzschmar H & Zerr I
Clinical features of rapidly progressive Alzheimer's disease.
Dementia and geriatric cognitive disorders, 2010, 29 (4) 371-8

Hillmer AS, Putcha P, Levin J, Högen T, Hyman BT, Kretzschmar H, McLean PJ & Giese A
Converse modulation of toxic alpha-synuclein oligomers in living cells by N'-benzylidene-benzohydrazide derivates and ferric iron.
Biochemical and biophysical research communications, 2010 Jan 01, 391 (1) 461-6

Kienast Y, von Baumgarten L, Fuhrmann M, Klinkert WE, Goldbrunner R, Herms J & Winkler F
Real-time imaging reveals the single steps of brain metastasis formation.
Nature medicine, 2010 Jan, 16 (1) 116-22

Durrenberger PF, Fernando S, Kashefi SN, Ferrer I, Hauw JJ, Seilhean D, Smith C, Walker R, Al-Sarraj S, Troakes C, Palkovits M, Kasztner M, Huitinga I, Arzberger T, Dexter DT, Kretzschmar H & Reynolds R
Effects of antemortem and postmortem variables on human brain mRNA quality: a BrainNet Europe study.
Journal of neuropathology and experimental neurology, 2010 Jan, 69 (1) 70-81

2009

Dreosti E, Odermatt B, Dorostkar MM & Lagnado L
A genetically encoded reporter of synaptic activity in vivo.
Nature methods, 2009 Dec, 6 (12) 883-9

Parchi P, Strammiello R, Notari S, Giese A, Langeveld JP, Ladogana A, Zerr I, Roncaroli F, Cras P, Ghetti B, Pocchiari M, Kretzschmar H & Capellari S
Incidence and spectrum of sporadic Creutzfeldt-Jakob disease variants with mixed phenotype and co-occurrence of PrPSc types: an updated classification.
Acta neuropathologica, 2009 Nov, 118 (5) 659-71

Neumann M, Roeber S, Kretzschmar HA, Rademakers R, Baker M & Mackenzie IR
Abundant FUS-immunoreactive pathology in neuronal intermediate filament inclusion disease.
Acta neuropathologica, 2009 Nov, 118 (5) 605-16

Neumann M, Rademakers R, Roeber S, Baker M, Kretzschmar HA & Mackenzie IR
A new subtype of frontotemporal lobar degeneration with FUS pathology.
Brain : a journal of neurology, 2009 Nov, 132 (Pt 11) 2922-31

Theodoropoulou M, Tichomirowa MA, Sievers C, Yassouridis A, Arzberger T, Hougrand O, Deprez M, Daly AF, Petrossians P, Pagotto U, Beckers A & Stalla GK
Tumor ZAC1 expression is associated with the response to somatostatin analog therapy in patients with acromegaly.
International journal of cancer, 2009 Nov 01, 125 (9) 2122-6

Gierga K, Schelhaas HJ, Brunt ER, Seidel K, Scherzed W, Egensperger R, de Vos RA, den Dunnen W, Ippel PF, Petrasch-Parwez E, Deller T, Schöls L & Rüb U
Spinocerebellar ataxia type 6 (SCA6): neurodegeneration goes beyond the known brain predilection sites.
Neuropathology and applied neurobiology, 2009 Oct, 35 (5) 515-27

Mitteregger G, Korte S, Shakarami M, Herms J & Kretzschmar HA
Role of copper and manganese in prion disease progression.
Brain research, 2009 Oct 06, 1292 155-64

Saunders GC, Lantier I, Cawthraw S, Berthon P, Moore SJ, Arnold ME, Windl O, Simmons MM, Andréoletti O, Bellworthy S & Lantier F
Protective effect of the T112 PrP variant in sheep challenged with bovine spongiform encephalopathy.
The Journal of general virology, 2009 Oct, 90 (Pt 10) 2569-2574

Rachinger W, Grau S, Holtmannspötter M, Herms J, Tonn JC & Kreth FW
Serial stereotactic biopsy of brainstem lesions in adults improves diagnostic accuracy compared with MRI only.
Journal of neurology, neurosurgery, and psychiatry, 2009 Oct, 80 (10) 1134-9

Winkler F, Kienast Y, Fuhrmann M, Von Baumgarten L, Burgold S, Mitteregger G, Kretzschmar H & Herms J
Imaging glioma cell invasion in vivo reveals mechanisms of dissemination and peritumoral angiogenesis.
Glia, 2009 Sep, 57 (12) 1306-15

Bittner T, Fuhrmann M, Burgold S, Jung CK, Volbracht C, Steiner H, Mitteregger G, Kretzschmar HA, Haass C & Herms J
Gamma-secretase inhibition reduces spine density in vivo via an amyloid precursor protein-dependent pathway.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009 Aug 19, 29 (33) 10405-9

Tribl F, Asan E, Arzberger T, Tatschner T, Langenfeld E, Meyer HE, Bringmann G, Riederer P, Gerlach M & Marcus K
Identification of L-ferritin in neuromelanin granules of the human substantia nigra: a targeted proteomics approach.
Molecular & cellular proteomics : MCP, 2009 Aug, 8 (8) 1832-8

Opherk C, Duering M, Peters N, Karpinska A, Rosner S, Schneider E, Bader B, Giese A & Dichgans M
CADASIL mutations enhance spontaneous multimerization of NOTCH3.
Human molecular genetics, 2009 Aug 01, 18 (15) 2761-7

Priller C, Mitteregger G, Paluch S, Vassallo N, Staufenbiel M, Kretzschmar HA, Jucker M & Herms J
Excitatory synaptic transmission is depressed in cultured hippocampal neurons of APP/PS1 mice.
Neurobiology of aging, 2009 Aug, 30 (8) 1227-37

Yoon MS, Katsarava Z, Obermann M, Schäfers M, Liedert B, Dzagnidze A, Kribben A, Egensperger R, Limmroth V, Diener HC & Thomale J
Erythropoietin overrides the triggering effect of DNA platination products in a mouse model of cisplatin-induced neuropathy.
BMC neuroscience, 2009 Jul 15, 10 77

Ammassari-Teule M, Sgobio C, Biamonte F, Marrone C, Mercuri NB & Keller F
Reelin haploinsufficiency reduces the density of PV+ neurons in circumscribed regions of the striatum and selectively alters striatal-based behaviors.
Psychopharmacology, 2009 Jun, 204 (3) 511-21

Alafuzoff I, Ince PG, Arzberger T, Al-Sarraj S, Bell J, Bodi I, Bogdanovic N, Bugiani O, Ferrer I, Gelpi E, Gentleman S, Giaccone G, Ironside JW, Kavantzas N, King A, Korkolopoulou P, Kovács GG, Meyronet D, Monoranu C, Parchi P, Parkkinen L, Patsouris E, Roggendorf W, Rozemuller A, Stadelmann-Nessler C, Streichenberger N, Thal DR & Kretzschmar H
Staging/typing of Lewy body related alpha-synuclein pathology: a study of the BrainNet Europe Consortium.
Acta neuropathologica, 2009 Jun, 117 (6) 635-52

Wolschner C, Giese A, Kretzschmar HA, Huber R, Moroder L & Budisa N
Design of anti- and pro-aggregation variants to assess the effects of methionine oxidation in human prion protein.
Proceedings of the National Academy of Sciences of the United States of America, 2009 May 12, 106 (19) 7756-61

Ghiglieri V, Picconi B, Sgobio C, Bagetta V, Barone I, Paillè V, Di Filippo M, Polli F, Gardoni F, Altrock W, Gundelfinger ED, De Sarro G, Bernardi G, Ammassari-Teule M, Di Luca M & Calabresi P
Epilepsy-induced abnormal striatal plasticity in Bassoon mutant mice.
The European journal of neuroscience, 2009 May, 29 (10) 1979-93

Cawthraw S, Saunders GC, Martin TC, Sawyer J, Windl O & Reaney SD
Real-time PCR detection and identification of prohibited mammalian and avian material in animal feeds.
Journal of food protection, 2009 May, 72 (5) 1055-62

Saunders GC, Cawthraw S, Mountjoy SJ, Tout AC, Sayers AR, Hope J & Windl O
Ovine PRNP untranslated region and promoter haplotype diversity.
The Journal of general virology, 2009 May, 90 (Pt 5) 1289-1293

Di Filippo M, Picconi B, Tantucci M, Ghiglieri V, Bagetta V, Sgobio C, Tozzi A, Parnetti L & Calabresi P
Short-term and long-term plasticity at corticostriatal synapses: implications for learning and memory.
Behavioural brain research, 2009 Apr 12, 199 (1) 108-18

Egaña LA, Cuevas RA, Baust TB, Parra LA, Leak RK, Hochendoner S, Peña K, Quiroz M, Hong WC, Dorostkar MM, Janz R, Sitte HH & Torres GE
Physical and functional interaction between the dopamine transporter and the synaptic vesicle protein synaptogyrin-3.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009 Apr 08, 29 (14) 4592-604

Mittelbronn M, Harter P, Warth A, Lupescu A, Schilbach K, Vollmann H, Capper D, Goeppert B, Frei K, Bertalanffy H, Weller M, Meyermann R, Lang F & Simon P
EGR-1 is regulated by N-methyl-D-aspartate-receptor stimulation and associated with patient survival in human high grade astrocytomas.
Brain pathology (Zurich, Switzerland), 2009 Apr, 19 (2) 195-204

Alafuzoff I, Thal DR, Arzberger T, Bogdanovic N, Al-Sarraj S, Bodi I, Boluda S, Bugiani O, Duyckaerts C, Gelpi E, Gentleman S, Giaccone G, Graeber M, Hortobagyi T, Höftberger R, Ince P, Ironside JW, Kavantzas N, King A, Korkolopoulou P, Kovács GG, Meyronet D, Monoranu C, Nilsson T, Parchi P, Patsouris E, Pikkarainen M, Revesz T, Rozemuller A, Seilhean D, Schulz-Schaeffer W, Streichenberger N, Wharton SB & Kretzschmar H
Assessment of beta-amyloid deposits in human brain: a study of the BrainNet Europe Consortium.
Acta neuropathologica, 2009 Mar, 117 (3) 309-20

Dewachter I, Filipkowski RK, Priller C, Ris L, Neyton J, Croes S, Terwel D, Gysemans M, Devijver H, Borghgraef P, Godaux E, Kaczmarek L, Herms J & Van Leuven F
Deregulation of NMDA-receptor function and down-stream signaling in APP[V717I] transgenic mice.
Neurobiology of aging, 2009 Feb, 30 (2) 241-56

González L, Martin S, Sisó S, Konold T, Ortiz-Peláez A, Phelan L, Goldmann W, Stewart P, Saunders G, Windl O, Jeffrey M, Hawkins SA, Dawson M & Hope J
High prevalence of scrapie in a dairy goat herd: tissue distribution of disease-associated PrP and effect of PRNP genotype and age.
Veterinary research, 2009, 40 (6) 65

Jeibmann A, Egensperger R, Kuchelmeister K, Sepehrnia A, Stolke D, Bruns B, Wassmann H, Ebel H, Paulus W & Hasselblatt M
Extent of surgical resection but not myxopapillary versus classical histopathological subtype affects prognosis in lumbo-sacral ependymomas.
Histopathology, 2009 Jan, 54 (2) 260-2

Levin J, Giese A, Boetzel K, Israel L, Högen T, Nübling G, Kretzschmar H & Lorenzl S
Increased alpha-synuclein aggregation following limited cleavage by certain matrix metalloproteinases.
Experimental neurology, 2009 Jan, 215 (1) 201-8

2008

Grau SJ, Trillsch F, von Lüttichau I, Nelson PJ, Herms J, Tonn JC & Goldbrunner RH
Lymphatic phenotype of tumour vessels in malignant gliomas.
Neuropathology and applied neurobiology, 2008 Dec, 34 (6) 675-9

Müller T, Jung K, Ullrich A, Schrötter A, Meyer HE, Stephan C, Egensperger R & Marcus K
Disease state, age, sex, and post-mortem time-dependent expression of proteins in AD vs. control frontal cortex brain samples.
Current Alzheimer research, 2008 Dec, 5 (6) 562-71

Notari S, Strammiello R, Capellari S, Giese A, Cescatti M, Grassi J, Ghetti B, Langeveld JP, Zou WQ, Gambetti P, Kretzschmar HA & Parchi P
Characterization of truncated forms of abnormal prion protein in Creutzfeldt-Jakob disease.
The Journal of biological chemistry, 2008 Nov 07, 283 (45) 30557-65

Hoche F, Seidel K, Brunt ER, Auburger G, Schöls L, Bürk K, de Vos RA, den Dunnen W, Bechmann I, Egensperger R, Van Broeckhoven C, Gierga K, Deller T & Rüb U
Involvement of the auditory brainstem system in spinocerebellar ataxia type 2 (SCA2), type 3 (SCA3) and type 7 (SCA7).
Neuropathology and applied neurobiology, 2008 Oct, 34 (5) 479-91

Alafuzoff I, Arzberger T, Al-Sarraj S, Bodi I, Bogdanovic N, Braak H, Bugiani O, Del-Tredici K, Ferrer I, Gelpi E, Giaccone G, Graeber MB, Ince P, Kamphorst W, King A, Korkolopoulou P, Kovács GG, Larionov S, Meyronet D, Monoranu C, Parchi P, Patsouris E, Roggendorf W, Seilhean D, Tagliavini F, Stadelmann C, Streichenberger N, Thal DR, Wharton SB & Kretzschmar H
Staging of neurofibrillary pathology in Alzheimer's disease: a study of the BrainNet Europe Consortium.
Brain pathology (Zurich, Switzerland), 2008 Oct, 18 (4) 484-96

Bagetta V, Barone I, Ghiglieri V, Di Filippo M, Sgobio C, Bernardi G, Calabresi P & Picconi B
Acetyl-L-Carnitine selectively prevents post-ischemic LTP via a possible action on mitochondrial energy metabolism.
Neuropharmacology, 2008 Aug, 55 (2) 223-9

Roeber S, Mackenzie IR, Kretzschmar HA & Neumann M
TDP-43-negative FTLD-U is a significant new clinico-pathological subtype of FTLD.
Acta neuropathologica, 2008 Aug, 116 (2) 147-57

Agrimi U, Nonno R, Dell'Omo G, Di Bari MA, Conte M, Chiappini B, Esposito E, Di Guardo G, Windl O, Vaccari G & Lipp HP
Prion protein amino acid determinants of differential susceptibility and molecular feature of prion strains in mice and voles.
PLoS pathogens, 2008 Jul 25, 4 (7) e1000113

Schicker KW, Dorostkar MM & Boehm S
Modulation of transmitter release via presynaptic ligand-gated ion channels.
Current molecular pharmacology, 2008 Jun, 1 (2) 106-29

Sgobio C, Trabalza A, Spalloni A, Zona C, Carunchio I, Longone P & Ammassari-Teule M
Abnormal medial prefrontal cortex connectivity and defective fear extinction in the presymptomatic G93A SOD1 mouse model of ALS.
Genes, brain, and behavior, 2008 Jun, 7 (4) 427-34

Roeber S, Grasbon-Frodl EM, Windl O, Krebs B, Xiang W, Vollmert C, Illig T, Schröter A, Arzberger T, Weber P, Zerr I & Kretzschmar HA
Evidence for a pathogenic role of different mutations at codon 188 of PRNP.
PloS one, 2008 May 14, 3 (5) e2147

Bell JE, Alafuzoff I, Al-Sarraj S, Arzberger T, Bogdanovic N, Budka H, Dexter DT, Falkai P, Ferrer I, Gelpi E, Gentleman SM, Giaccone G, Huitinga I, Ironside JW, Klioueva N, Kovacs GG, Meyronet D, Palkovits M, Parchi P, Patsouris E, Reynolds R, Riederer P, Roggendorf W, Seilhean D, Schmitt A, Schmitz P, Streichenberger N, Schwalber A & Kretzschmar H
Management of a twenty-first century brain bank: experience in the BrainNet Europe consortium.
Acta neuropathologica, 2008 May, 115 (5) 497-507

Alafuzoff I, Pikkarainen M, Arzberger T, Thal DR, Al-Sarraj S, Bell J, Bodi I, Budka H, Capetillo-Zarate E, Ferrer I, Gelpi E, Gentleman S, Giaccone G, Kavantzas N, King A, Korkolopoulou P, Kovács GG, Meyronet D, Monoranu C, Parchi P, Patsouris E, Roggendorf W, Stadelmann C, Streichenberger N, Tagliavini F & Kretzschmar H
Inter-laboratory comparison of neuropathological assessments of beta-amyloid protein: a study of the BrainNet Europe consortium.
Acta neuropathologica, 2008 May, 115 (5) 533-46

Mehrkens JH, Pöpperl G, Rachinger W, Herms J, Seelos K, Tatsch K, Tonn JC & Kreth FW
The positive predictive value of O-(2-[18F]fluoroethyl)-L-tyrosine (FET) PET in the diagnosis of a glioma recurrence after multimodal treatment.
Journal of neuro-oncology, 2008 May, 88 (1) 27-35

Weber P, Reznicek L, Mitteregger G, Kretzschmar H & Giese A
Differential effects of prion particle size on infectivity in vivo and in vitro.
Biochemical and biophysical research communications, 2008 May 09, 369 (3) 924-8

Kostka M, Högen T, Danzer KM, Levin J, Habeck M, Wirth A, Wagner R, Glabe CG, Finger S, Heinzelmann U, Garidel P, Duan W, Ross CA, Kretzschmar H & Giese A
Single particle characterization of iron-induced pore-forming alpha-synuclein oligomers.
The Journal of biological chemistry, 2008 Apr 18, 283 (16) 10992-1003

Schüller U, Ruiter M, Herms J, Kretzschmar HA & Grasbon-Frodl E
Absence of mutations in the AKT1 oncogene in glioblastomas and medulloblastomas.
Acta neuropathologica, 2008 Mar, 115 (3) 367-8

Crecelius A, Götz A, Arzberger T, Fröhlich T, Arnold GJ, Ferrer I & Kretzschmar HA
Assessing quantitative post-mortem changes in the gray matter of the human frontal cortex proteome by 2-D DIGE.
Proteomics, 2008 Mar, 8 (6) 1276-91

Stummer W, Beck T, Beyer W, Mehrkens JH, Obermeier A, Etminan N, Stepp H, Tonn JC, Baumgartner R, Herms J & Kreth FW
Long-sustaining response in a patient with non-resectable, distant recurrence of glioblastoma multiforme treated by interstitial photodynamic therapy using 5-ALA: case report.
Journal of neuro-oncology, 2008 Mar, 87 (1) 103-9

Alafuzoff I, Parkkinen L, Al-Sarraj S, Arzberger T, Bell J, Bodi I, Bogdanovic N, Budka H, Ferrer I, Gelpi E, Gentleman S, Giaccone G, Kamphorst W, King A, Korkolopoulou P, Kovács GG, Larionov S, Meyronet D, Monoranu C, Morris J, Parchi P, Patsouris E, Roggendorf W, Seilhean D, Streichenberger N, Thal DR, Kretzschmar H & BrainNet Europe Consortium
Assessment of alpha-synuclein pathology: a study of the BrainNet Europe Consortium.
Journal of neuropathology and experimental neurology, 2008 Feb, 67 (2) 125-43

Kovacs GG, Alafuzoff I, Al-Sarraj S, Arzberger T, Bogdanovic N, Capellari S, Ferrer I, Gelpi E, Kövari V, Kretzschmar H, Nagy Z, Parchi P, Seilhean D, Soininen H, Troakes C & Budka H
Mixed brain pathologies in dementia: the BrainNet Europe consortium experience.
Dementia and geriatric cognitive disorders, 2008, 26 (4) 343-50

Picconi B, Ghiglieri V, Bagetta V, Barone I, Sgobio C & Calabresi P
Striatal synaptic changes in experimental parkinsonism: role of NMDA receptor trafficking in PSD.
Parkinsonism & related disorders, 2008, 14 Suppl 2 S145-9

Bojarski L, Herms J & Kuznicki J
Calcium dysregulation in Alzheimer's disease.
Neurochemistry international, 2008, 52 (4-5) 621-33

Linn J, Herms J, Dichgans M, Brückmann H, Fesl G, Freilinger T & Wiesmann M
Subarachnoid hemosiderosis and superficial cortical hemosiderosis in cerebral amyloid angiopathy.
AJNR. American journal of neuroradiology, 2008 Jan, 29 (1) 184-6

Friedrich M, Körte R, Portero C, Arzberger T, Kretzschmar HA, Zerr I & Nacimiento W
[Fatal familial insomnia--a rare differential diagnosis in dementia].
Fortschritte der Neurologie-Psychiatrie, 2008 Jan, 76 (1) 36-40

Dorostkar MM & Boehm S
Presynaptic lonotropic receptors.
Handbook of experimental pharmacology, 2008, (184) 479-527

2007

Pöpperl G, Kreth FW, Mehrkens JH, Herms J, Seelos K, Koch W, Gildehaus FJ, Kretzschmar HA, Tonn JC & Tatsch K
FET PET for the evaluation of untreated gliomas: correlation of FET uptake and uptake kinetics with tumour grading.
European journal of nuclear medicine and molecular imaging, 2007 Dec, 34 (12) 1933-42

Grünblatt E, Zander N, Bartl J, Jie L, Monoranu CM, Arzberger T, Ravid R, Roggendorf W, Gerlach M & Riederer P
Comparison analysis of gene expression patterns between sporadic Alzheimer's and Parkinson's disease.
Journal of Alzheimer's disease : JAD, 2007 Dec, 12 (4) 291-311

Notari S, Capellari S, Langeveld J, Giese A, Strammiello R, Gambetti P, Kretzschmar HA & Parchi P
A refined method for molecular typing reveals that co-occurrence of PrP(Sc) types in Creutzfeldt-Jakob disease is not the rule.
Laboratory investigation; a journal of technical methods and pathology, 2007 Nov, 87 (11) 1103-12

Krumbholz M, Theil D, Steinmeyer F, Cepok S, Hemmer B, Hofbauer M, Farina C, Derfuss T, Junker A, Arzberger T, Sinicina I, Hartle C, Newcombe J, Hohlfeld R & Meinl E
CCL19 is constitutively expressed in the CNS, up-regulated in neuroinflammation, active and also inactive multiple sclerosis lesions.
Journal of neuroimmunology, 2007 Oct, 190 (1-2) 72-9

Saunders GC, Horigan V, Tout AC & Windl O
Identification of a proteinase K resistant protein for use as an internal positive control marker in PrP Western blotting.
Research in veterinary science, 2007 Oct, 83 (2) 157-64

Mittelbronn M, Simon P, Löffler C, Capper D, Bunz B, Harter P, Schlaszus H, Schleich A, Tabatabai G, Goeppert B, Meyermann R, Weller M & Wischhusen J
Elevated HLA-E levels in human glioblastomas but not in grade I to III astrocytomas correlate with infiltrating CD8+ cells.
Journal of neuroimmunology, 2007 Sep, 189 (1-2) 50-8

Weber P, Giese A, Piening N, Mitteregger G, Thomzig A, Beekes M & Kretzschmar HA
Generation of genuine prion infectivity by serial PMCA.
Veterinary microbiology, 2007 Aug 31, 123 (4) 346-57

Danzer KM, Haasen D, Karow AR, Moussaud S, Habeck M, Giese A, Kretzschmar H, Hengerer B & Kostka M
Different species of alpha-synuclein oligomers induce calcium influx and seeding.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007 Aug 22, 27 (34) 9220-32

Xiang W, Hummel M, Mitteregger G, Pace C, Windl O, Mansmann U & Kretzschmar HA
Transcriptome analysis reveals altered cholesterol metabolism during the neurodegeneration in mouse scrapie model.
Journal of neurochemistry, 2007 Aug, 102 (3) 834-47

Hamid R, Kilger E, Willem M, Vassallo N, Kostka M, Bornhövd C, Reichert AS, Kretzschmar HA, Haass C & Herms J
Amyloid precursor protein intracellular domain modulates cellular calcium homeostasis and ATP content.
Journal of neurochemistry, 2007 Aug, 102 (4) 1264-75

Ring S, Weyer SW, Kilian SB, Waldron E, Pietrzik CU, Filippov MA, Herms J, Buchholz C, Eckman CB, Korte M, Wolfer DP & Müller UC
The secreted beta-amyloid precursor protein ectodomain APPs alpha is sufficient to rescue the anatomical, behavioral, and electrophysiological abnormalities of APP-deficient mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007 Jul 18, 27 (29) 7817-26

Scharpf M, Schweizer U, Arzberger T, Roggendorf W, Schomburg L & Köhrle J
Neuronal and ependymal expression of selenoprotein P in the human brain.
Journal of neural transmission (Vienna, Austria : 1996), 2007 Jul, 114 (7) 877-84

Ferrer I, Armstrong J, Capellari S, Parchi P, Arzberger T, Bell J, Budka H, Ströbel T, Giaccone G, Rossi G, Bogdanovic N, Fakai P, Schmitt A, Riederers P, Al-Sarraj S, Ravid R & Kretzschmar H
Effects of formalin fixation, paraffin embedding, and time of storage on DNA preservation in brain tissue: a BrainNet Europe study.
Brain pathology (Zurich, Switzerland), 2007 Jul, 17 (3) 297-303

Fuhrmann M, Mitteregger G, Kretzschmar H & Herms J
Dendritic pathology in prion disease starts at the synaptic spine.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007 Jun 06, 27 (23) 6224-33

Grau SJ, Trillsch F, Herms J, Thon N, Nelson PJ, Tonn JC & Goldbrunner R
Expression of VEGFR3 in glioma endothelium correlates with tumor grade.
Journal of neuro-oncology, 2007 Apr, 82 (2) 141-50

Saunders GC, Griffiths PC, Cawthraw S, Tout AC, Wiener P, Woolliams JA, Williams JL & Windl O
Polymorphisms of the prion protein gene coding region in born-after-the-reinforced-ban (BARB) bovine spongiform encephalopathy cattle in Great Britain.
The Journal of general virology, 2007 Apr, 88 (Pt 4) 1374-1378

Schiffer NW, Broadley SA, Hirschberger T, Tavan P, Kretzschmar HA, Giese A, Haass C, Hartl FU & Schmid B
Identification of anti-prion compounds as efficient inhibitors of polyglutamine protein aggregation in a zebrafish model.
The Journal of biological chemistry, 2007 Mar 23, 282 (12) 9195-203

Jacob CP, Koutsilieri E, Bartl J, Neuen-Jacob E, Arzberger T, Zander N, Ravid R, Roggendorf W, Riederer P & Grünblatt E
Alterations in expression of glutamatergic transporters and receptors in sporadic Alzheimer's disease.
Journal of Alzheimer's disease : JAD, 2007 Mar, 11 (1) 97-116

Middei S, Vetere G, Sgobio C & Ammassari-Teule M
Landmark-based but not vestibular-based orientation elicits mossy fiber synaptogenesis in the mouse hippocampus.
Neurobiology of learning and memory, 2007 Feb, 87 (2) 174-80

Sostak P, Theil D, Stepp H, Roeber S, Kretzschmar HA & Straube A
Detection of bone marrow-derived cells expressing a neural phenotype in the human brain.
Journal of neuropathology and experimental neurology, 2007 Feb, 66 (2) 110-6

Priller C, Dewachter I, Vassallo N, Paluch S, Pace C, Kretzschmar HA, Van Leuven F & Herms J
Mutant presenilin 1 alters synaptic transmission in cultured hippocampal neurons.
The Journal of biological chemistry, 2007 Jan 12, 282 (2) 1119-27

Wagner I, Sethi S, Xiang W, Giese A, Ebner S & Kretzschmar H
Repeated peripheral administrations of CpG oligodeoxynucleotides lead to sustained CNS immune activation.
Immunopharmacology and immunotoxicology, 2007, 29 (3-4) 413-24

Tribl F, Arzberger T, Riederer P & Gerlach M
Tyrosinase is not detected in human catecholaminergic neurons by immunohistochemistry and Western blot analysis.
Journal of neural transmission. Supplementum, 2007, (72) 51-5

Schmitt A, Bauer M, Heinsen H, Feiden W, Consortium of Brainnet Europe II, Falkai P, Alafuzoff I, Arzberger T, Al-Sarraj S, Bell JE, Bogdanovic N, Brück W, Budka H, Ferrer I, Giaccone G, Kovacs GG, Meyronet D, Palkovits M, Parchi P, Patsouris E, Ravid R, Reynolds R, Riederer P, Roggendorf W, Schwalber A, Seilhean D & Kretzschmar H
How a neuropsychiatric brain bank should be run: a consensus paper of Brainnet Europe II.
Journal of neural transmission (Vienna, Austria : 1996), 2007, 114 (5) 527-37

Riemann K, Adamzik M, Frauenrath S, Egensperger R, Schmid KW, Brockmeyer NH & Siffert W
Comparison of manual and automated nucleic acid extraction from whole-blood samples.
Journal of clinical laboratory analysis, 2007, 21 (4) 244-8

Krebs B, Wiebelitz A, Balitzki-Korte B, Vassallo N, Paluch S, Mitteregger G, Onodera T, Kretzschmar HA & Herms J
Cellular prion protein modulates the intracellular calcium response to hydrogen peroxide.
Journal of neurochemistry, 2007 Jan, 100 (2) 358-67

Müller T, Concannon CG, Ward MW, Walsh CM, Tirniceriu AL, Tribl F, Kögel D, Prehn JH & Egensperger R
Modulation of gene expression and cytoskeletal dynamics by the amyloid precursor protein intracellular domain (AICD).
Molecular biology of the cell, 2007 Jan, 18 (1) 201-10

Ferrer I, Santpere G, Arzberger T, Bell J, Blanco R, Boluda S, Budka H, Carmona M, Giaccone G, Krebs B, Limido L, Parchi P, Puig B, Strammiello R, Ströbel T & Kretzschmar H
Brain protein preservation largely depends on the postmortem storage temperature: implications for study of proteins in human neurologic diseases and management of brain banks: a BrainNet Europe Study.
Journal of neuropathology and experimental neurology, 2007 Jan, 66 (1) 35-46

2006

Jeibmann A, Hasselblatt M, Gerss J, Wrede B, Egensperger R, Beschorner R, Hans VH, Rickert CH, Wolff JE & Paulus W
Prognostic implications of atypical histologic features in choroid plexus papilloma.
Journal of neuropathology and experimental neurology, 2006 Nov, 65 (11) 1069-73

Saunders GC, Cawthraw S, Mountjoy SJ, Hope J & Windl O
PrP genotypes of atypical scrapie cases in Great Britain.
The Journal of general virology, 2006 Nov, 87 (Pt 11) 3141-3149

Weber P, Giese A, Piening N, Mitteregger G, Thomzig A, Beekes M & Kretzschmar HA
Cell-free formation of misfolded prion protein with authentic prion infectivity.
Proceedings of the National Academy of Sciences of the United States of America, 2006 Oct 24, 103 (43) 15818-23

Braak H, Alafuzoff I, Arzberger T, Kretzschmar H & Del Tredici K
Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry.
Acta neuropathologica, 2006 Oct, 112 (4) 389-404

Marrone MC, Marinelli S, Biamonte F, Keller F, Sgobio CA, Ammassari-Teule M, Bernardi G & Mercuri NB
Altered cortico-striatal synaptic plasticity and related behavioural impairments in reeler mice.
The European journal of neuroscience, 2006 Oct, 24 (7) 2061-70

Vollmert C, Windl O, Xiang W, Rosenberger A, Zerr I, Wichmann HE, Bickeböller H, Illig T, KORA group & Kretzschmar HA
Significant association of a M129V independent polymorphism in the 5' UTR of the PRNP gene with sporadic Creutzfeldt-Jakob disease in a large German case-control study.
Journal of medical genetics, 2006 Oct, 43 (10) e53

Behrends C, Langer CA, Boteva R, Böttcher UM, Stemp MJ, Schaffar G, Rao BV, Giese A, Kretzschmar H, Siegers K & Hartl FU
Chaperonin TRiC promotes the assembly of polyQ expansion proteins into nontoxic oligomers.
Molecular cell, 2006 Sep 15, 23 (6) 887-97

Fröhlich T, Helmstetter D, Zobawa M, Crecelius AC, Arzberger T, Kretzschmar HA & Arnold GJ
Analysis of the HUPO Brain Proteome reference samples using 2-D DIGE and 2-D LC-MS/MS.
Proteomics, 2006 Sep, 6 (18) 4950-66

Fuhrmann M, Bittner T, Mitteregger G, Haider N, Moosmang S, Kretzschmar H & Herms J
Loss of the cellular prion protein affects the Ca2+ homeostasis in hippocampal CA1 neurons.
Journal of neurochemistry, 2006 Sep, 98 (6) 1876-85

Krasnianski A, Schulz-Schaeffer WJ, Kallenberg K, Meissner B, Collie DA, Roeber S, Bartl M, Heinemann U, Varges D, Kretzschmar HA & Zerr I
Clinical findings and diagnostic tests in the MV2 subtype of sporadic CJD.
Brain : a journal of neurology, 2006 Sep, 129 (Pt 9) 2288-96

Riemenschneider M, Konta L, Friedrich P, Schwarz S, Taddei K, Neff F, Padovani A, Kölsch H, Laws SM, Klopp N, Bickeböller H, Wagenpfeil S, Mueller JC, Rosenberger A, Diehl-Schmid J, Archetti S, Lautenschlager N, Borroni B, Müller U, Illig T, Heun R, Egensperger R, Schlegel J, Förstl H, Martins RN & Kurz A
A functional polymorphism within plasminogen activator urokinase (PLAU) is associated with Alzheimer's disease.
Human molecular genetics, 2006 Aug 15, 15 (16) 2446-56

Alafuzoff I, Pikkarainen M, Al-Sarraj S, Arzberger T, Bell J, Bodi I, Bogdanovic N, Budka H, Bugiani O, Ferrer I, Gelpi E, Giaccone G, Graeber MB, Hauw JJ, Kamphorst W, King A, Kopp N, Korkolopoulou P, Kovács GG, Meyronet D, Parchi P, Patsouris E, Preusser M, Ravid R, Roggendorf W, Seilhean D, Streichenberger N, Thal DR & Kretzschmar H
Interlaboratory comparison of assessments of Alzheimer disease-related lesions: a study of the BrainNet Europe Consortium.
Journal of neuropathology and experimental neurology, 2006 Aug, 65 (8) 740-57

Roeber S, Bäzner H, Hennerici M, Porstmann R & Kretzschmar HA
Neurodegeneration with features of NIFID and ALS--extended clinical and neuropathological spectrum.
Brain pathology (Zurich, Switzerland), 2006 Jul, 16 (3) 228-34

Priller C, Bauer T, Mitteregger G, Krebs B, Kretzschmar HA & Herms J
Synapse formation and function is modulated by the amyloid precursor protein.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006 Jul 05, 26 (27) 7212-21

Piening N, Weber P, Högen T, Beekes M, Kretzschmar H & Giese A
Photo-induced crosslinking of prion protein oligomers and prions.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis, 2006 Jun, 13 (2) 67-77

Milojevic T, Reiterer V, Stefan E, Korkhov VM, Dorostkar MM, Ducza E, Ogris E, Boehm S, Freissmuth M & Nanoff C
The ubiquitin-specific protease Usp4 regulates the cell surface level of the A2A receptor.
Molecular pharmacology, 2006 Apr, 69 (4) 1083-94

Picconi B, Passino E, Sgobio C, Bonsi P, Barone I, Ghiglieri V, Pisani A, Bernardi G, Ammassari-Teule M & Calabresi P
Plastic and behavioral abnormalities in experimental Huntington's disease: a crucial role for cholinergic interneurons.
Neurobiology of disease, 2006 Apr, 22 (1) 143-52

Piening N, Nonno R, Di Bari M, Walter S, Windl O, Agrimi U, Kretzschmar HA & Bertsch U
Conversion efficiency of bank vole prion protein in vitro is determined by residues 155 and 170, but does not correlate with the high susceptibility of bank voles to sheep scrapie in vivo.
The Journal of biological chemistry, 2006 Apr 07, 281 (14) 9373-84

Barnewitz K, Maringer M, Mitteregger G, Giese A, Bertsch U & Kretzschmar HA
Unaltered prion protein cleavage in plasminogen-deficient mice.
Neuroreport, 2006 Apr 03, 17 (5) 527-30

Pöpperl G, Kreth FW, Herms J, Koch W, Mehrkens JH, Gildehaus FJ, Kretzschmar HA, Tonn JC & Tatsch K
Analysis of 18F-FET PET for grading of recurrent gliomas: is evaluation of uptake kinetics superior to standard methods?
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2006 Mar, 47 (3) 393-403

Spalloni A, Geracitano R, Berretta N, Sgobio C, Bernardi G, Mercuri NB, Longone P & Ammassari-Teule M
Molecular and synaptic changes in the hippocampus underlying superior spatial abilities in pre-symptomatic G93A+/+ mice overexpressing the human Cu/Zn superoxide dismutase (Gly93 --> ALA) mutation.
Experimental neurology, 2006 Feb, 197 (2) 505-14

Krebs B, Dorner-Ciossek C, Schmalzbauer R, Vassallo N, Herms J & Kretzschmar HA
Prion protein induced signaling cascades in monocytes.
Biochemical and biophysical research communications, 2006 Feb 03, 340 (1) 13-22

Goetze B, Tuebing F, Xie Y, Dorostkar MM, Thomas S, Pehl U, Boehm S, Macchi P & Kiebler MA
The brain-specific double-stranded RNA-binding protein Staufen2 is required for dendritic spine morphogenesis.
The Journal of cell biology, 2006 Jan 16, 172 (2) 221-31

2005

Windl O, Buchholz M, Neubauer A, Schulz-Schaeffer W, Groschup M, Walter S, Arendt S, Neumann M, Voss AK & Kretzschmar HA
Breaking an absolute species barrier: transgenic mice expressing the mink PrP gene are susceptible to transmissible mink encephalopathy.
Journal of virology, 2005 Dec, 79 (23) 14971-5

Hilber B, Scholze P, Dorostkar MM, Sandtner W, Holy M, Boehm S, Singer EA & Sitte HH
Serotonin-transporter mediated efflux: a pharmacological analysis of amphetamines and non-amphetamines.
Neuropharmacology, 2005 Nov, 49 (6) 811-9

Zecca L, Berg D, Arzberger T, Ruprecht P, Rausch WD, Musicco M, Tampellini D, Riederer P, Gerlach M & Becker G
In vivo detection of iron and neuromelanin by transcranial sonography: a new approach for early detection of substantia nigra damage.
Movement disorders : official journal of the Movement Disorder Society, 2005 Oct, 20 (10) 1278-85

Boesenberg C, Schulz-Schaeffer WJ, Meissner B, Kallenberg K, Bartl M, Heinemann U, Krasnianski A, Stoeck K, Varges D, Windl O, Kretzschmar HA & Zerr I
Clinical course in young patients with sporadic Creutzfeldt-Jakob disease.
Annals of neurology, 2005 Oct, 58 (4) 533-43

Rachinger W, Goetz C, Pöpperl G, Gildehaus FJ, Kreth FW, Holtmannspötter M, Herms J, Koch W, Tatsch K & Tonn JC
Positron emission tomography with O-(2-[18F]fluoroethyl)-l-tyrosine versus magnetic resonance imaging in the diagnosis of recurrent gliomas.
Neurosurgery, 2005 Sep, 57 (3) 505-11; discussion 505-11

Giese A, Bader B, Bieschke J, Schaffar G, Odoy S, Kahle PJ, Haass C & Kretzschmar H
Single particle detection and characterization of synuclein co-aggregation.
Biochemical and biophysical research communications, 2005 Aug 12, 333 (4) 1202-10

Restivo L, Ferrari F, Passino E, Sgobio C, Bock J, Oostra BA, Bagni C & Ammassari-Teule M
Enriched environment promotes behavioral and morphological recovery in a mouse model for the fragile X syndrome.
Proceedings of the National Academy of Sciences of the United States of America, 2005 Aug 09, 102 (32) 11557-62

Xiang W, Windl O, Westner IM, Neumann M, Zerr I, Lederer RM & Kretzschmar HA
Cerebral gene expression profiles in sporadic Creutzfeldt-Jakob disease.
Annals of neurology, 2005 Aug, 58 (2) 242-57

Koch HJ, Roeber S, Zimmermann UW, Schäfer C, Villarrubia V, Kuchelmeister K, Schachenmayr W, Bogdahn U & Steinbrecher A
[Spinal and cerebral leptomeningeal seeding from a melanocytoma of the cerebello-pontine angle].
Wiener medizinische Wochenschrift (1946), 2005 Aug, 155 (15-16) 360-4

Cartoni C, Schininà ME, Maras B, Nonno R, Vaccari G, Di Baria MA, Conte M, Liu QG, Lu M, Cardone F, Windl O, Pocchiari M & Agrimi U
Identification of the pathological prion protein allotypes in scrapie-infected heterozygous bank voles (Clethrionomys glareolus) by high-performance liquid chromatography-mass spectrometry.
Journal of chromatography. A, 2005 Jul 15, 1081 (1) 122-6

Tribl F, Gerlach M, Marcus K, Asan E, Tatschner T, Arzberger T, Meyer HE, Bringmann G & Riederer P
"Subcellular proteomics" of neuromelanin granules isolated from the human brain.
Molecular & cellular proteomics : MCP, 2005 Jul, 4 (7) 945-57

Sarafoff NI, Bieschke J, Giese A, Weber P, Bertsch U & Kretzschmar HA
Automated PrPres amplification using indirect sonication.
Journal of biochemical and biophysical methods, 2005 Jun 30, 63 (3) 213-21

Vassallo N, Herms J, Behrens C, Krebs B, Saeki K, Onodera T, Windl O & Kretzschmar HA
Activation of phosphatidylinositol 3-kinase by cellular prion protein and its role in cell survival.
Biochemical and biophysical research communications, 2005 Jun 24, 332 (1) 75-82

Weiss E, Albrecht CF, Herms J, Behnke-Mursch J, Pekrun A, Brockmann K & Hess CF
Malignant ectomesenchymoma of the cerebrum. Case report and discussion of therapeutic options.
European journal of pediatrics, 2005 Jun, 164 (6) 345-9

Bertsch U, Winklhofer KF, Hirschberger T, Bieschke J, Weber P, Hartl FU, Tavan P, Tatzelt J, Kretzschmar HA & Giese A
Systematic identification of antiprion drugs by high-throughput screening based on scanning for intensely fluorescent targets.
Journal of virology, 2005 Jun, 79 (12) 7785-91

Krebs B, Lederer RM, Windl O, Grasbon-Frodl EM, Zerr I & Kretzschmar HA
Creutzfeldt-Jakob disease associated with an R148H mutation of the prion protein gene.
Neurogenetics, 2005 May, 6 (2) 97-100

Levin J, Bertsch U, Kretzschmar H & Giese A
Single particle analysis of manganese-induced prion protein aggregates.
Biochemical and biophysical research communications, 2005 Apr 22, 329 (4) 1200-7

Roeber S, Krebs B, Neumann M, Windl O, Zerr I, Grasbon-Frodl EM & Kretzschmar HA
Creutzfeldt-Jakob disease in a patient with an R208H mutation of the prion protein gene (PRNP) and a 17-kDa prion protein fragment.
Acta neuropathologica, 2005 Apr, 109 (4) 443-8

Stork M, Giese A, Kretzschmar HA & Tavan P
Molecular dynamics simulations indicate a possible role of parallel beta-helices in seeded aggregation of poly-Gln.
Biophysical journal, 2005 Apr, 88 (4) 2442-51

Perron H, Lazarini F, Ruprecht K, Péchoux-Longin C, Seilhean D, Sazdovitch V, Créange A, Battail-Poirot N, Sibaï G, Santoro L, Jolivet M, Darlix JL, Rieckmann P, Arzberger T, Hauw JJ & Lassmann H
Human endogenous retrovirus (HERV)-W ENV and GAG proteins: physiological expression in human brain and pathophysiological modulation in multiple sclerosis lesions.
Journal of neurovirology, 2005 Feb, 11 (1) 23-33

Piening N, Weber P, Giese A & Kretzschmar H
Breakage of PrP aggregates is essential for efficient autocatalytic propagation of misfolded prion protein.
Biochemical and biophysical research communications, 2005 Jan 14, 326 (2) 339-43

Giese A, Buchholz M, Herms J & Kretzschmar HA
Mouse brain synaptosomes accumulate copper-67 efficiently by two distinct processes independent of cellular prion protein.
Journal of molecular neuroscience : MN, 2005, 27 (3) 347-54

2004

Drisaldi B, Coomaraswamy J, Mastrangelo P, Strome B, Yang J, Watts JC, Chishti MA, Marvi M, Windl O, Ahrens R, Major F, Sy MS, Kretzschmar H, Fraser PE, Mount HT & Westaway D
Genetic mapping of activity determinants within cellular prion proteins: N-terminal modules in PrPC offset pro-apoptotic activity of the Doppel helix B/B' region.
The Journal of biological chemistry, 2004 Dec 31, 279 (53) 55443-54

Grasbon-Frodl E, Schmalzbauer R, Weber P, Krebs B, Windl O, Zerr I & Kretzschmar HA
A novel three extra-repeat insertion in the prion protein gene (PRNP) in a patient with Creutzfeldt-Jakob disease.
Neurogenetics, 2004 Dec, 5 (4) 249-50

Lechner SG, Dorostkar MM, Mayer M, Edelbauer H, Pankevych H & Boehm S
Autoinhibition of transmitter release from PC12 cells and sympathetic neurons through a P2Y receptor-mediated inhibition of voltage-gated Ca2+ channels.
The European journal of neuroscience, 2004 Dec, 20 (11) 2917-28

Grasbon-Frodl E, Lorenz H, Mann U, Nitsch RM, Windl O & Kretzschmar HA
Loss of glycosylation associated with the T183A mutation in human prion disease.
Acta neuropathologica, 2004 Dec, 108 (6) 476-84

Theodoropoulou M, Arzberger T, Gruebler Y, Jaffrain-Rea ML, Schlegel J, Schaaf L, Petrangeli E, Losa M, Stalla GK & Pagotto U
Expression of epidermal growth factor receptor in neoplastic pituitary cells: evidence for a role in corticotropinoma cells.
The Journal of endocrinology, 2004 Nov, 183 (2) 385-94

Herms J, Anliker B, Heber S, Ring S, Fuhrmann M, Kretzschmar H, Sisodia S & Müller U
Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members.
The EMBO journal, 2004 Oct 13, 23 (20) 4106-15

Schüller U, Schober F, Kretzschmar HA & Herms J
Bcl-2 expression inversely correlates with tumour cell differentiation in medulloblastoma.
Neuropathology and applied neurobiology, 2004 Oct, 30 (5) 513-21

Xiang W, Windl O, Wünsch G, Dugas M, Kohlmann A, Dierkes N, Westner IM & Kretzschmar HA
Identification of differentially expressed genes in scrapie-infected mouse brains by using global gene expression technology.
Journal of virology, 2004 Oct, 78 (20) 11051-60

Uspenskaia O, Liebetrau M, Herms J, Danek A & Hamann GF
Aging is associated with increased collagen type IV accumulation in the basal lamina of human cerebral microvessels.
BMC neuroscience, 2004 Sep 24, 5 37

Banati RB, Egensperger R, Maassen A, Hager G, Kreutzberg GW & Graeber MB
Mitochondria in activated microglia in vitro.
Journal of neurocytology, 2004 Sep, 33 (5) 535-41

Bieschke J, Weber P, Sarafoff N, Beekes M, Giese A & Kretzschmar H
Autocatalytic self-propagation of misfolded prion protein.
Proceedings of the National Academy of Sciences of the United States of America, 2004 Aug 17, 101 (33) 12207-11

Meissner B, Körtner K, Bartl M, Jastrow U, Mollenhauer B, Schröter A, Finkenstaedt M, Windl O, Poser S, Kretzschmar HA & Zerr I
Sporadic Creutzfeldt-Jakob disease: magnetic resonance imaging and clinical findings.
Neurology, 2004 Aug 10, 63 (3) 450-6

Giese A, Levin J, Bertsch U & Kretzschmar H
Effect of metal ions on de novo aggregation of full-length prion protein.
Biochemical and biophysical research communications, 2004 Aug 06, 320 (4) 1240-6

Ozen O, Krebs B, Hemmerlein B, Pekrun A, Kretzschmar H & Herms J
Expression of matrix metalloproteinases and their inhibitors in medulloblastomas and their prognostic relevance.
Clinical cancer research : an official journal of the American Association for Cancer Research, 2004 Jul 15, 10 (14) 4746-53

Farhan H, Korkhov VM, Paulitschke V, Dorostkar MM, Scholze P, Kudlacek O, Freissmuth M & Sitte HH
Two discontinuous segments in the carboxyl terminus are required for membrane targeting of the rat gamma-aminobutyric acid transporter-1 (GAT1).
The Journal of biological chemistry, 2004 Jul 02, 279 (27) 28553-63

Theodoropoulou M, Cavallari I, Barzon L, D'Agostino DM, Ferro T, Arzberger T, Grübler Y, Schaaf L, Losa M, Fallo F, Ciminale V, Stalla GK & Pagotto U
Differential expression of menin in sporadic pituitary adenomas.
Endocrine-related cancer, 2004 Jun, 11 (2) 333-44

Harder A, Gregor A, Wirth T, Kreuz F, Schulz-Schaeffer WJ, Windl O, Plotkin M, Amthauer H, Neukirch K, Kretzschmar HA, Kuhlmann T, Braas R, Hahne HH & Jendroska K
Early age of onset in fatal familial insomnia. Two novel cases and review of the literature.
Journal of neurology, 2004 Jun, 251 (6) 715-24

Dzierzega-Lecznar A, Kurkiewicz S, Stepien K, Chodurek E, Wilczok T, Arzberger T, Riederer P & Gerlach M
GC/MS analysis of thermally degraded neuromelanin from the human substantia nigra.
Journal of the American Society for Mass Spectrometry, 2004 Jun, 15 (6) 920-6

Notari S, Capellari S, Giese A, Westner I, Baruzzi A, Ghetti B, Gambetti P, Kretzschmar HA & Parchi P
Effects of different experimental conditions on the PrPSc core generated by protease digestion: implications for strain typing and molecular classification of CJD.
The Journal of biological chemistry, 2004 Apr 16, 279 (16) 16797-804

Otto M, Cepek L, Ratzka P, Doehlinger S, Boekhoff I, Wiltfang J, Irle E, Pergande G, Ellers-Lenz B, Windl O, Kretzschmar HA, Poser S & Prange H
Efficacy of flupirtine on cognitive function in patients with CJD: A double-blind study.
Neurology, 2004 Mar 09, 62 (5) 714-8

Peraud A, Herms J, Schlegel J, Müller P, Kretzschmar H & Tonn JC
Recurrent spinal cord astrocytoma with intraventricular seeding.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2004 Feb, 20 (2) 114-8

2003

van der Knaap MS, van Berkel CG, Herms J, van Coster R, Baethmann M, Naidu S, Boltshauser E, Willemsen MA, Plecko B, Hoffmann GF, Proud CG, Scheper GC & Pronk JC
eIF2B-related disorders: antenatal onset and involvement of multiple organs.
American journal of human genetics, 2003 Nov, 73 (5) 1199-207

Korte S, Vassallo N, Kramer ML, Kretzschmar HA & Herms J
Modulation of L-type voltage-gated calcium channels by recombinant prion protein.
Journal of neurochemistry, 2003 Nov, 87 (4) 1037-42

Gerlach M, Double K, Arzberger T, Leblhuber F, Tatschner T & Riederer P
Dopamine receptor agonists in current clinical use: comparative dopamine receptor binding profiles defined in the human striatum.
Journal of neural transmission (Vienna, Austria : 1996), 2003 Oct, 110 (10) 1119-27

Hopt A, Korte S, Fink H, Panne U, Niessner R, Jahn R, Kretzschmar H & Herms J
Methods for studying synaptosomal copper release.
Journal of neuroscience methods, 2003 Sep 30, 128 (1-2) 159-72

Vassallo N & Herms J
Cellular prion protein function in copper homeostasis and redox signalling at the synapse.
Journal of neurochemistry, 2003 Aug, 86 (3) 538-44

Kretzschmar HA, Sethi S, Földvári Z, Windl O, Querner V, Zerr I & Poser S
Latrogenic Creutzfeldt-Jakob disease with florid plaques.
Brain pathology (Zurich, Switzerland), 2003 Jul, 13 (3) 245-9

Erdlenbruch B, Schinkhof C, Kugler W, Heinemann DE, Herms J, Eibl H & Lakomek M
Intracarotid administration of short-chain alkylglycerols for increased delivery of methotrexate to the rat brain.
British journal of pharmacology, 2003 Jun, 139 (4) 685-94

Herms J, Schneider I, Dewachter I, Caluwaerts N, Kretzschmar H & Van Leuven F
Capacitive calcium entry is directly attenuated by mutant presenilin-1, independent of the expression of the amyloid precursor protein.
The Journal of biological chemistry, 2003 Jan 24, 278 (4) 2484-9

Bönnemann CG, Thompson TG, van der Ven PF, Goebel HH, Warlo I, Vollmers B, Reimann J, Herms J, Gautel M, Takada F, Beggs AH, Fürst DO, Kunkel LM, Hanefeld F & Schröder R
Filamin C accumulation is a strong but nonspecific immunohistochemical marker of core formation in muscle.
Journal of the neurological sciences, 2003 Jan 15, 206 (1) 71-8

Kösel S, Lücking CB, Egensperger R & Graeber MB
Nonradioactive PCR sequencing using digoxigenin.
Methods in molecular biology (Clifton, N.J.), 2003, 226 347-54

2002

Ubl A, Berg D, Holzmann C, Krüger R, Berger K, Arzberger T, Bornemann A & Riess O
14-3-3 protein is a component of Lewy bodies in Parkinson's disease-mutation analysis and association studies of 14-3-3 eta.
Brain research. Molecular brain research, 2002 Dec, 108 (1-2) 33-9

Tschampa HJ, Herms JW, Schulz-Schaeffer WJ, Maruschak B, Windl O, Jastrow U, Zerr I, Steinhoff BJ, Poser S & Kretzschmar HA
Clinical findings in sporadic Creutzfeldt-Jakob disease correlate with thalamic pathology.
Brain : a journal of neurology, 2002 Nov, 125 (Pt 11) 2558-66

Petri S, Krampfl K, Dengler R, Bufler J, Weindl A & Arzberger T
Human GABA A receptors on dopaminergic neurons in the pars compacta of the substantia nigra.
The Journal of comparative neurology, 2002 Oct 28, 452 (4) 360-6

Achim C, Auer R, Bergeron C, Cardozo A, Deprez M, de Vos R, Duyckaerts C, Egensperger R, Esiri M, Frosch MP, Giannini C, Goebel HH, Graeber MB, Graham DI, Gray F, Haltia M, Hashizume Y, Ikeda K, Ironside JW, Kreutzberg GW, Lantos P, Lowe J, Ludwin S, Matsumoto Y, Olsson Y, Sasaki A, Scheithauer BW, Takahashi H, Tolnay M, Trojanowski JQ, Troost D & de F Webster H
Global democratic consensus on neuropathological disease criteria.
The Lancet. Neurology, 2002 Oct, 1 (6) 340

Hansen IA, Jakob O, Wortmann S, Arzberger T, Allolio B & Blind E
Characterization of the human and mouse genes encoding the tuberoinfundibular peptide of 39 residues, a ligand of the parathyroid hormone receptor family.
The Journal of endocrinology, 2002 Jul, 174 (1) 95-102

Lange M, Pagotto U, Renner U, Arzberger T, Oeckler R & Stalla GK
The role of endothelins in the regulation of pituitary function.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2002 May, 110 (3) 103-12

Wegner C, Römer A, Schmalzbauer R, Lorenz H, Windl O & Kretzschmar HA
Mutant prion protein acquires resistance to protease in mouse neuroblastoma cells.
The Journal of general virology, 2002 May, 83 (Pt 5) 1237-1245

Lorenz H, Windl O & Kretzschmar HA
Cellular phenotyping of secretory and nuclear prion proteins associated with inherited prion diseases.
The Journal of biological chemistry, 2002 Mar 08, 277 (10) 8508-16

Schmidt T, Lindenberg KS, Krebs A, Schöls L, Laccone F, Herms J, Rechsteiner M, Riess O & Landwehrmeyer GB
Protein surveillance machinery in brains with spinocerebellar ataxia type 3: redistribution and differential recruitment of 26S proteasome subunits and chaperones to neuronal intranuclear inclusions.
Annals of neurology, 2002 Mar, 51 (3) 302-10

Tumani H, Windl O, Kretzschmar HA & Ludolph AC
[Clinically atypical CJD: diagnostic relevance of cerebrospinal fluid markers and molecular genetic analysis?].
Deutsche medizinische Wochenschrift (1946), 2002 Feb 15, 127 (7) 318-20

Winkelmann J, Pagotto U, Theodoropoulou M, Tatsch K, Saeger W, Müller A, Arzberger T, Schaaf L, Schumann EM, Trenkwalder C & Stalla GK
Retention of dopamine 2 receptor mRNA and absence of the protein in craniospinal and extracranial metastasis of a malignant prolactinoma: a case report.
European journal of endocrinology, 2002 Jan, 146 (1) 81-8

2001

Reuther FJ, Löhler J, Herms J, Hugo HH, Schindler C, Leithäuser F, Melzner I, Möller P & Scheil S
Low incidence of SV40-like sequences in ependymal tumours.
The Journal of pathology, 2001 Dec, 195 (5) 580-5

Middel P, Reich K, Polzien F, Blaschke V, Hemmerlein B, Herms J, Korabiowska M & Radzun HJ
Interleukin 16 expression and phenotype of interleukin 16 producing cells in Crohn's disease.
Gut, 2001 Dec, 49 (6) 795-803

Scheil S, Brüderlein S, Liehr T, Starke H, Herms J, Schulte M & Möller P
Genome-wide analysis of sixteen chordomas by comparative genomic hybridization and cytogenetics of the first human chordoma cell line, U-CH1.
Genes, chromosomes & cancer, 2001 Nov, 32 (3) 203-11

Egensperger R, Scheithauer BW, Horvath E, Kovacs K, Giannini C, Young WF, Lloyd R, Atkinson J & Nippoldt TB
Cushing's disease due to plurihormonal adrenocorticotropic hormone and gonadotropin-producing pituitary adenoma.
Acta neuropathologica, 2001 Oct, 102 (4) 398-403

Reusche E, Pilz P, Oberascher G, Lindner B, Egensperger R, Gloeckner K, Trinka E & Iglseder B
Subacute fatal aluminum encephalopathy after reconstructive otoneurosurgery: a case report.
Human pathology, 2001 Oct, 32 (10) 1136-40

Brück W, Herms J, Brockmann K, Schulz-Schaeffer W & Hanefeld F
Myelinopathia centralis diffusa (vanishing white matter disease): evidence of apoptotic oligodendrocyte degeneration in early lesion development.
Annals of neurology, 2001 Oct, 50 (4) 532-6

Pagotto U, Marsicano G, Fezza F, Theodoropoulou M, Grübler Y, Stalla J, Arzberger T, Milone A, Losa M, Di Marzo V, Lutz B & Stalla GK
Normal human pituitary gland and pituitary adenomas express cannabinoid receptor type 1 and synthesize endogenous cannabinoids: first evidence for a direct role of cannabinoids on hormone modulation at the human pituitary level.
The Journal of clinical endocrinology and metabolism, 2001 Jun, 86 (6) 2687-96

Kramer ML, Kratzin HD, Schmidt B, Römer A, Windl O, Liemann S, Hornemann S & Kretzschmar H
Prion protein binds copper within the physiological concentration range.
The Journal of biological chemistry, 2001 May 18, 276 (20) 16711-9

Oehmichen M, Schulz-Schaeffer W, Kretzschmar H, Theuerkauf I, Gerling I, Windl O & Meissner C
Creutzfeldt-Jakob disease (CJD) in a case of suspected chronic heavy metal poisoning.
Journal of forensic sciences, 2001 May, 46 (3) 702-7

Schneider I, Reverse D, Dewachter I, Ris L, Caluwaerts N, Kuiperi C, Gilis M, Geerts H, Kretzschmar H, Godaux E, Moechars D, Van Leuven F & Herms J
Mutant presenilins disturb neuronal calcium homeostasis in the brain of transgenic mice, decreasing the threshold for excitotoxicity and facilitating long-term potentiation.
The Journal of biological chemistry, 2001 Apr 13, 276 (15) 11539-44

Scheil S, Brüderlein S, Eicker M, Herms J, Herold-Mende C, Steiner HH, Barth TF & Möller P
Low frequency of chromosomal imbalances in anaplastic ependymomas as detected by comparative genomic hybridization.
Brain pathology (Zurich, Switzerland), 2001 Apr, 11 (2) 133-43

Herms JW, Tings T, Dunker S & Kretzschmar HA
Prion protein affects Ca2+-activated K+ currents in cerebellar purkinje cells.
Neurobiology of disease, 2001 Apr, 8 (2) 324-30

Papós M, Pekrun A, Herms JW, Behr TM, Meller J, Rustenbeck HH, Kretzschmar HA & Becker W
Somatostatin receptor scintigraphy in the management of cerebral malignant ectomesenchymoma: a case report.
Pediatric radiology, 2001 Mar, 31 (3) 169-72

Dürig J, Giese A, Schmücker U, Kretzschmar HA & Dührsen U
Decreased prion protein expression in human peripheral blood leucocytes from patients with paroxysmal nocturnal haemoglobinuria.
British journal of haematology, 2001 Mar, 112 (3) 658-62

Kretzschmar HA, Tings T, Madlung A, Giese A & Herms J
Prion protein as copper-binding protein at the synapse.
Methods in molecular medicine, 2001, 59 17-30

Giese A & Kretzschmar HA
Prion-induced neuronal damage--the mechanisms of neuronal destruction in the subacute spongiform encephalopathies.
Current topics in microbiology and immunology, 2001, 253 203-17

Mueller W, Lass U, Herms J, Kuchelmeister K, Bergmann M & von Deimling A
Clonal analysis in glioblastoma with epithelial differentiation.
Brain pathology (Zurich, Switzerland), 2001 Jan, 11 (1) 39-43

Augustin I, Korte S, Rickmann M, Kretzschmar HA, Südhof TC, Herms JW & Brose N
The cerebellum-specific Munc13 isoform Munc13-3 regulates cerebellar synaptic transmission and motor learning in mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001 Jan 01, 21 (1) 10-7

2000

Pagotto U, Arzberger T, Theodoropoulou M, Grübler Y, Pantaloni C, Saeger W, Losa M, Journot L, Stalla GK & Spengler D
The expression of the antiproliferative gene ZAC is lost or highly reduced in nonfunctioning pituitary adenomas.
Cancer research, 2000 Dec 15, 60 (24) 6794-9

Heber S, Herms J, Gajic V, Hainfellner J, Aguzzi A, Rülicke T, von Kretzschmar H, von Koch C, Sisodia S, Tremml P, Lipp HP, Wolfer DP & Müller U
Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000 Nov 01, 20 (21) 7951-63

Theodoropoulou M, Arzberger T, Gruebler Y, Korali Z, Mortini P, Joba W, Heufelder AE, Stalla GK & Schaaf L
Thyrotrophin receptor protein expression in normal and adenomatous human pituitary.
The Journal of endocrinology, 2000 Oct, 167 (1) 7-13

Herms JW, Korte S, Gall S, Schneider I, Dunker S & Kretzschmar HA
Altered intracellular calcium homeostasis in cerebellar granule cells of prion protein-deficient mice.
Journal of neurochemistry, 2000 Oct, 75 (4) 1487-92

Herms J, Neidt I, Lüscher B, Sommer A, Schürmann P, Schröder T, Bergmann M, Wilken B, Probst-Cousin S, Hernáiz-Driever P, Behnke J, Hanefeld F, Pietsch T & Kretzschmar HA
C-MYC expression in medulloblastoma and its prognostic value.
International journal of cancer, 2000 Sep 20, 89 (5) 395-402

von Eitzen U, Kösel S, Grasbon-Frodl EM, Egensperger R & Graeber MB
Sequence analysis of the MTCYB gene in Parkinson disease.
Neurogenetics, 2000 Sep, 3 (1) 47-8

Zerr I, Schulz-Schaeffer WJ, Giese A, Bodemer M, Schröter A, Henkel K, Tschampa HJ, Windl O, Pfahlberg A, Steinhoff BJ, Gefeller O, Kretzschmar HA & Poser S
Current clinical diagnosis in Creutzfeldt-Jakob disease: identification of uncommon variants.
Annals of neurology, 2000 Sep, 48 (3) 323-9

Fayyazi A, Schweyer S, Eichmeyer B, Herms J, Hemmerlein B, Radzun HJ & Berger H
Expression of IFNgamma, coexpression of TNFalpha and matrix metalloproteinases and apoptosis of T lymphocytes and macrophages in granuloma annulare.
Archives of dermatological research, 2000 Aug, 292 (8) 384-90

Fayyazi A, Eichmeyer B, Soruri A, Schweyer S, Herms J, Schwarz P & Radzun HJ
Apoptosis of macrophages and T cells in tuberculosis associated caseous necrosis.
The Journal of pathology, 2000 Aug, 191 (4) 417-25

Wilken B, Dechent P, Herms J, Maxton C, Markakis E, Hanefeld F & Frahm J
Quantitative proton magnetic resonance spectroscopy of focal brain lesions.
Pediatric neurology, 2000 Jul, 23 (1) 22-31

Bieschke J, Giese A, Schulz-Schaeffer W, Zerr I, Poser S, Eigen M & Kretzschmar H
Ultrasensitive detection of pathological prion protein aggregates by dual-color scanning for intensely fluorescent targets.
Proceedings of the National Academy of Sciences of the United States of America, 2000 May 09, 97 (10) 5468-73

Müller-Vahl KR, Kolbe H, Egensperger R & Dengler R
Mitochondriopathy, blepharospasm, and treatment with botulinum toxin.
Muscle & nerve, 2000 Apr, 23 (4) 647-8

Muller-Vahl KR, Kolbe H, Egensperger R & Dengler R
AAEM news and comments.
Muscle & nerve, 2000 Apr, 23 (4) 651-4

Otto M, Esselmann H, Schulz-Shaeffer W, Neumann M, Schröter A, Ratzka P, Cepek L, Zerr I, Steinacker P, Windl O, Kornhuber J, Kretzschmar HA, Poser S & Wiltfang J
Decreased beta-amyloid1-42 in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease.
Neurology, 2000 Mar 14, 54 (5) 1099-102

Dürig J, Giese A, Schulz-Schaeffer W, Rosenthal C, Schmücker U, Bieschke J, Dührsen U & Kretzschmar HA
Differential constitutive and activation-dependent expression of prion protein in human peripheral blood leucocytes.
British journal of haematology, 2000 Mar, 108 (3) 488-95

Giese A, Bieschke J, Eigen M & Kretzschmar HA
Putting prions into focus: application of single molecule detection to the diagnosis of prion diseases.
Archives of virology. Supplementum, 2000, (16) 161-71

Kretzschmar HA, Tings T, Madlung A, Giese A & Herms J
Function of PrP(C) as a copper-binding protein at the synapse.
Archives of virology. Supplementum, 2000, (16) 239-49

Poser S, Zerr I, Schroeter A, Otto M, Giese A, Steinhoff BJ & Kretzschmar HA
Clinical and differential diagnosis of Creutzfeldt-Jakob disease.
Archives of virology. Supplementum, 2000, (16) 153-9

Widjaja A, Mix H, Gölkel C, Flemming P, Egensperger R, Holstein A, Rademaker J, Becker H, Hundt M, Wagner S & Manns MP
Uncommon metastasis of a glioblastoma multiforme in liver and spleen.
Digestion, 2000, 61 (3) 219-22

Schulz-Schaeffer WJ, Tschöke S, Kranefuss N, Dröse W, Hause-Reitner D, Giese A, Groschup MH & Kretzschmar HA
The paraffin-embedded tissue blot detects PrP(Sc) early in the incubation time in prion diseases.
The American journal of pathology, 2000 Jan, 156 (1) 51-6

1999

Heim C, Arzberger T, Sontag T, Xiao A, Herbinger KH, Weindl A & Sontag KH
Progressive degeneration of dopamine system functions after transient cerebral oligemia in rats.
Brain research, 1999 Dec 18, 851 (1-2) 235-46

Harder A, Jendroska K, Kreuz F, Wirth T, Schafranka C, Karnatz N, Théallier-Janko A, Dreier J, Lohan K, Emmerich D, Cervós-Navarro J, Windl O, Kretzschmar HA, Nürnberg P & Witkowski R
Novel twelve-generation kindred of fatal familial insomnia from germany representing the entire spectrum of disease expression.
American journal of medical genetics, 1999 Dec 03, 87 (4) 311-6

Skworc KH, Windl O, Schulz-Schaeffer WJ, Giese A, Bergk J, Nägele A, Vieregge P, Zerr I, Poser S & Kretzschmar HA
Familial Creutzfeldt-Jakob disease with a novel 120-bp insertion in the prion protein gene.
Annals of neurology, 1999 Nov, 46 (5) 693-700

Skworc KH, Windl O, Schulz-Schaeffer WJ, Giese A, Bergk J, Nagele A, Vieregge P, Zerr I, Poser S & Kretzschmar HA
Familial Creutzfeldt-Jakob disease with a novel 120-bp insertion in the prion protein gene.
Annals of neurology, 1999 Nov, 46 (5) 693-700

Herms J, Tings T, Gall S, Madlung A, Giese A, Siebert H, Schürmann P, Windl O, Brose N & Kretzschmar H
Evidence of presynaptic location and function of the prion protein.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999 Oct 15, 19 (20) 8866-75

Windl O, Giese A, Schulz-Schaeffer W, Zerr I, Skworc K, Arendt S, Oberdieck C, Bodemer M, Poser S & Kretzschmar HA
Molecular genetics of human prion diseases in Germany.
Human genetics, 1999 Sep, 105 (3) 244-52

Bayer TA, Jäkälä P, Hartmann T, Egensperger R, Buslei R, Falkai P & Beyreuther K
Neural expression profile of alpha-synuclein in developing human cortex.
Neuroreport, 1999 Sep 09, 10 (13) 2799-803

Tolnay M, Calhoun M, Pham HC, Egensperger R & Probst A
Low amyloid (Abeta) plaque load and relative predominance of diffuse plaques distinguish argyrophilic grain disease from Alzheimer's disease.
Neuropathology and applied neurobiology, 1999 Aug, 25 (4) 295-305

Parchi P, Giese A, Capellari S, Brown P, Schulz-Schaeffer W, Windl O, Zerr I, Budka H, Kopp N, Piccardo P, Poser S, Rojiani A, Streichemberger N, Julien J, Vital C, Ghetti B, Gambetti P & Kretzschmar H
Classification of sporadic Creutzfeldt-Jakob disease based on molecular and phenotypic analysis of 300 subjects.
Annals of neurology, 1999 Aug, 46 (2) 224-33

Herms JW, von Loewenich FD, Behnke J, Markakis E & Kretzschmar HA
c-myc oncogene family expression in glioblastoma and survival.
Surgical neurology, 1999 May, 51 (5) 536-42

Egensperger R, Weggen S, Ida N, Multhaup G, Schnabel R, Beyreuther K & Bayer TA
Reverse relationship between beta-amyloid precursor protein and beta-amyloid peptide plaques in Down's syndrome versus sporadic/familial Alzheimer's disease.
Acta neuropathologica, 1999 Feb, 97 (2) 113-8

Pagotto U, Arzberger T, Ciani E, Lezoualc'h F, Pilon C, Journot L, Spengler D & Stalla GK
Inhibition of Zac1, a new gene differentially expressed in the anterior pituitary, increases cell proliferation.
Endocrinology, 1999 Feb, 140 (2) 987-96

Grasbon-Frodl EM, Egensperger R, Kösel S, Krüger R, Riess O, Mehraein P & Graeber MB
The alpha1-antichymotrypsin A-allele in German Parkinson disease patients.
Journal of neural transmission (Vienna, Austria : 1996), 1999, 106 (7-8) 729-36

Ehrenreich H, Oldenburg J, Hasselblatt M, Herms J, Dembowski C, Löffler BM, Brück W, Kamrowski-Kruck H, Gall S, Sirén AL & Schilling L
Endothelin B receptor-deficient rats as a subtraction model to study the cerebral endothelin system.
Neuroscience, 1999, 91 (3) 1067-75

Schramm M, Falkai P, Pietsch T, Neidt I, Egensperger R & Bayer TA
Neural expression profile of Elav-like genes in human brain.
Clinical neuropathology, 1999, 18 (1) 17-22

Almer G, Hainfellner JA, Brücke T, Jellinger K, Kleinert R, Bayer G, Windl O, Kretzschmar HA, Hill A, Sidle K, Collinge J & Budka H
Fatal familial insomnia: a new Austrian family.
Brain : a journal of neurology, 1999 Jan, 122 ( Pt 1) 5-16

Windl O, Lorenz H, Behrens C, R Mer A & Kretzschmar HA
Construction and characterization of murine neuroblastoma cell clones allowing inducible and high expression of the prion protein.
The Journal of general virology, 1999 Jan, 80 ( Pt 1) 15-21

Kropp S, Schulz-Schaeffer WJ, Finkenstaedt M, Riedemann C, Windl O, Steinhoff BJ, Zerr I, Kretzschmar HA & Poser S
The Heidenhain variant of Creutzfeldt-Jakob disease.
Archives of neurology, 1999 Jan, 56 (1) 55-61

1998

Zerr I, Giese A, Windl O, Kropp S, Schulz-Schaeffer W, Riedemann C, Skworc K, Bodemer M, Kretzschmar HA & Poser S
Phenotypic variability in fatal familial insomnia (D178N-129M) genotype.
Neurology, 1998 Nov, 51 (5) 1398-405

Tolnay M, Probst A, Monsch AU, Staehelin HB & Egensperger R
Apolipoprotein E allele frequencies in argyrophilic grain disease.
Acta neuropathologica, 1998 Sep, 96 (3) 225-7

Tran CT, Wolz P, Egensperger R, Kösel S, Imai Y, Bise K, Kohsaka S, Mehraein P & Graeber MB
Differential expression of MHC class II molecules by microglia and neoplastic astroglia: relevance for the escape of astrocytoma cells from immune surveillance.
Neuropathology and applied neurobiology, 1998 Aug, 24 (4) 293-301

Egensperger R, Kösel S, von Eitzen U & Graeber MB
Microglial activation in Alzheimer disease: Association with APOE genotype.
Brain pathology (Zurich, Switzerland), 1998 Jul, 8 (3) 439-47

Kretzschmar H, Giese A, Zerr I, Windl O, Schulz-Schaeffer W, Skworc K & Poser S
The German FFI cases.
Brain pathology (Zurich, Switzerland), 1998 Jul, 8 (3) 559-61

Giese A, Brown DR, Groschup MH, Feldmann C, Haist I & Kretzschmar HA
Role of microglia in neuronal cell death in prion disease.
Brain pathology (Zurich, Switzerland), 1998 Jul, 8 (3) 449-57

von zur Mühlen F, Klass C, Kreuzer H, Mall G, Giese A & Reimers CD
Cardiac involvement in proximal myotonic myopathy.
Heart (British Cardiac Society), 1998 Jun, 79 (6) 619-21

Brown DR, Besinger A, Herms JW & Kretzschmar HA
Microglial expression of the prion protein.
Neuroreport, 1998 May 11, 9 (7) 1425-9

Renner U, Arzberger T, Pagotto U, Leimgruber S, Uhl E, Müller A, Lange M, Weindl A & Stalla GK
Heterogeneous dopamine D2 receptor subtype messenger ribonucleic acid expression in clinically nonfunctioning pituitary adenomas.
The Journal of clinical endocrinology and metabolism, 1998 Apr, 83 (4) 1368-75

Kösel S, Grasbon-Frodl EM, Mautsch U, Egensperger R, von Eitzen U, Frishman D, Hofmann S, Gerbitz KD, Mehraein P & Graeber MB
Novel mutations of mitochondrial complex I in pathologically proven Parkinson disease.
Neurogenetics, 1998 Mar, 1 (3) 197-204

v Eitzen U, Egensperger R, Kösel S, Grasbon-Frodl EM, Imai Y, Bise K, Kohsaka S, Mehraein P & Graeber MB
Microglia and the development of spongiform change in Creutzfeldt-Jakob disease.
Journal of neuropathology and experimental neurology, 1998 Mar, 57 (3) 246-56

Warzok RW, Kessler C, Apel G, Schwarz A, Egensperger R, Schreiber D, Herbst EW, Wolf E, Walther R & Walker LC
Apolipoprotein E4 promotes incipient Alzheimer pathology in the elderly.
Alzheimer disease and associated disorders, 1998 Mar, 12 (1) 33-9

Otto M, Wiltfang J, Schütz E, Zerr I, Otto A, Pfahlberg A, Gefeller O, Uhr M, Giese A, Weber T, Kretzschmar HA & Poser S
Diagnosis of Creutzfeldt-Jakob disease by measurement of S100 protein in serum: prospective case-control study.
BMJ (Clinical research ed.), 1998 Feb 21, 316 (7131) 577-82

Bergmann M, Pietsch T, Herms J, Janus J, Spaar HJ & Terwey B
Medullomyoblastoma: a histological, immunohistochemical, ultrastructural and molecular genetic study.
Acta neuropathologica, 1998 Feb, 95 (2) 205-12

Egensperger R, Herrmann H, Kösel S & Graeber MB
Association between ACT polymorphism and Alzheimer's disease.
Neurology, 1998 Feb, 50 (2) 575-6

Zerr I, Bodemer M, Gefeller O, Otto M, Poser S, Wiltfang J, Windl O, Kretzschmar HA & Weber T
Detection of 14-3-3 protein in the cerebrospinal fluid supports the diagnosis of Creutzfeldt-Jakob disease.
Annals of neurology, 1998 Jan, 43 (1) 32-40

1997

Bancher C, Egensperger R, Kösel S, Jellinger K & Graeber MB
Low prevalence of apolipoprotein E epsilon 4 allele in the neurofibrillary tangle predominant form of senile dementia.
Acta neuropathologica, 1997 Nov, 94 (5) 403-9

Herms JW, Madlung A, Brown DR & Kretzschmar HA
Increase of intracellular free Ca2+ in microglia activated by prion protein fragment.
Glia, 1997 Oct, 21 (2) 253-7

Kösel S, Egensperger R, Schnopp NM & Graeber MB
The 'common deletion' is not increased in parkinsonian substantia nigra as shown by competitive polymerase chain reaction.
Movement disorders : official journal of the Movement Disorder Society, 1997 Sep, 12 (5) 639-45

Egensperger R, Kösel S, Schnopp NM, Mehraein P & Graeber MB
Association of the mitochondrial tRNA(A4336G) mutation with Alzheimer's and Parkinson's diseases.
Neuropathology and applied neurobiology, 1997 Aug, 23 (4) 315-21

Maslim J, Valter K, Egensperger R, Holländer H & Stone J
Tissue oxygen during a critical developmental period controls the death and survival of photoreceptors.
Investigative ophthalmology & visual science, 1997 Aug, 38 (9) 1667-77

Brown DR, Herms JW, Schmidt B & Kretzschmar HA
PrP and beta-amyloid fragments activate different neurotoxic mechanisms in cultured mouse cells.
The European journal of neuroscience, 1997 Jun, 9 (6) 1162-9

Graeber MB, Kösel S, Egensperger R, Banati RB, Müller U, Bise K, Hoff P, Möller HJ, Fujisawa K & Mehraein P
Rediscovery of the case described by Alois Alzheimer in 1911: historical, histological and molecular genetic analysis.
Neurogenetics, 1997 May, 1 (1) 73-80

Arzberger T, Krampfl K, Leimgruber S & Weindl A
Changes of NMDA receptor subunit (NR1, NR2B) and glutamate transporter (GLT1) mRNA expression in Huntington's disease--an in situ hybridization study.
Journal of neuropathology and experimental neurology, 1997 Apr, 56 (4) 440-54

Parchi P, Capellari S, Chen SG, Petersen RB, Gambetti P, Kopp N, Brown P, Kitamoto T, Tateishi J, Giese A & Kretzschmar H
Typing prion isoforms.
Nature, 1997 Mar 20, 386 (6622) 232-4

Kösel S, Egensperger R, von Eitzen U, Mehraein P & Graeber MB
On the question of apoptosis in the parkinsonian substantia nigra.
Acta neuropathologica, 1997 Feb, 93 (2) 105-8

Herms JW, Behnke J, Bergmann M, Christen HJ, Kolb R, Wilkening M, Markakis E, Hanefeld F & Kretzschmar HA
Potential prognostic value of C-erbB-2 expression in medulloblastomas in very young children.
Journal of pediatric hematology/oncology, 1997, 19 (6) 510-5

Schallock K, Schulz-Schaeffer WJ, Giese A & Kretzschmar HA
Postmortem delay and temperature conditions affect the in situ end-labeling (ISEL) assay in brain tissue of mice.
Clinical neuropathology, 1997, 16 (3) 133-6

Kretzschmar HA, Giese A, Brown DR, Herms J, Keller B, Schmidt B & Groschup M
Cell death in prion disease.
Journal of neural transmission. Supplementum, 1997, 50 191-210

Brown DR, Qin K, Herms JW, Madlung A, Manson J, Strome R, Fraser PE, Kruck T, von Bohlen A, Schulz-Schaeffer W, Giese A, Westaway D & Kretzschmar H
The cellular prion protein binds copper in vivo.
Nature, 1997, 390 (6661) 684-7

1996

Egensperger R, Maslim J, Bisti S, Holländer H & Stone J
Fate of DNA from retinal cells dying during development: uptake by microglia and macroglia (Müller cells).
Brain research. Developmental brain research, 1996 Nov 22, 97 (1) 1-8

Weis J, Kretzschmar HA, Windl O, Podoll K & Schwarz M
Fatal spongiform encephalopathy in a patient who had handled animal feed.
Lancet (London, England), 1996 Nov 02, 348 (9036) 1240

Zerr I, Bodemer M, Otto M, Poser S, Windl O, Kretzschmar HA, Gefeller O & Weber T
Diagnosis of Creutzfeldt-Jakob disease by two-dimensional gel electrophoresis of cerebrospinal fluid.
Lancet (London, England), 1996 Sep 28, 348 (9031) 846-9

Windl O, Dempster M, Estibeiro JP, Lathe R, de Silva R, Esmonde T, Will R, Springbett A, Campbell TA, Sidle KC, Palmer MS & Collinge J
Genetic basis of Creutzfeldt-Jakob disease in the United Kingdom: a systematic analysis of predisposing mutations and allelic variation in the PRNP gene.
Human genetics, 1996 Sep, 98 (3) 259-64

Kurz A, Egensperger R, Haupt M, Lautenschlager N, Romero B, Graeber MB & Müller U
Apolipoprotein E epsilon 4 allele, cognitive decline, and deterioration of everyday performance in Alzheimer's disease.
Neurology, 1996 Aug, 47 (2) 440-3

Egensperger R, Bancher C, Kösel S, Jellinger K, Mehraein P & Graeber MB
The apolipoprotein E epsilon 4 allele in Parkinson's disease with Alzheimer lesions.
Biochemical and biophysical research communications, 1996 Jul 16, 224 (2) 484-6

Jahn K, Bufler J, Weindl A, Arzberger T & Hatt H
Patch-clamp study on membrane properties and transmitter activated currents of rabbit area postrema neurons.
Journal of comparative physiology. A, Sensory, neural, and behavioral physiology, 1996 Jun, 178 (6) 771-8

Kösel S, Lücking CB, Egensperger R, Mehraein P & Graeber MB
Mitochondrial NADH dehydrogenase and CYP2D6 genotypes in Lewy-body parkinsonism.
Journal of neuroscience research, 1996 Apr 15, 44 (2) 174-83

Zurmöhle U, Herms J, Schlingensiepen R, Brysch W & Schlingensiepen KH
Changes in the expression of synapsin I and II messenger RNA during postnatal rat brain development.
Experimental brain research, 1996 Mar, 108 (3) 441-9

Kösel S, Lücking CB, Egensperger R & Graeber MB
Nonradioactive PCR sequencing using digoxigenin.
Methods in molecular biology (Clifton, N.J.), 1996, 65 81-9

Schnopp NM, Kösel S, Egensperger R & Graeber MB
Regional heterogeneity of mtDNA heteroplasmy in parkinsonian brain.
Clinical neuropathology, 1996, 15 (6) 348-52

Schulz-Schaeffer WJ, Giese A, Windl O & Kretzschmar HA
Polymorphism at codon 129 of the prion protein gene determines cerebellar pathology in Creutzfeldt-Jakob disease.
Clinical neuropathology, 1996, 15 (6) 353-7

1995

Herms JW, Kretzchmar HA, Titz S & Keller BU
Patch-clamp analysis of synaptic transmission to cerebellar purkinje cells of prion protein knockout mice.
The European journal of neuroscience, 1995 Dec 01, 7 (12) 2508-12

Pagotto U, Arzberger T, Hopfner U, Sauer J, Renner U, Newton CJ, Lange M, Uhl E, Weindl A & Stalla GK
Expression and localization of endothelin-1 and endothelin receptors in human meningiomas. Evidence for a role in tumoral growth.
The Journal of clinical investigation, 1995 Oct, 96 (4) 2017-25

Giese A, Groschup MH, Hess B & Kretzschmar HA
Neuronal cell death in scrapie-infected mice is due to apoptosis.
Brain pathology (Zurich, Switzerland), 1995 Jul, 5 (3) 213-21

Windl O, Dempster M, Estibeiro P & Lathe R
A candidate marsupial PrP gene reveals two domains conserved in mammalian PrP proteins.
Gene, 1995 Jul 04, 159 (2) 181-6

Pagotto U, Arzberger T, Hopfner U, Weindl A & Stalla GK
Cellular localization of endothelin receptor mRNAs (ETA and ETB) in brain tumors and normal human brain.
Journal of cardiovascular pharmacology, 1995, 26 Suppl 3 S104-6

Kurz A, Egensperger R, Lautenschlager N, Haupt M, Altland K, Graeber MB & Müller U
[The apolipoprotein E gene and Alzheimer disease phenotype].
Zeitschrift fur Gerontologie und Geriatrie, 1995, 28 (3) 195-9

Nicholl D, Windl O, de Silva R, Sawcer S, Dempster M, Ironside JW, Estibeiro JP, Yuill GM, Lathe R & Will RG
Inherited Creutzfeldt-Jakob disease in a British family associated with a novel 144 base pair insertion of the prion protein gene.
Journal of neurology, neurosurgery, and psychiatry, 1995 Jan, 58 (1) 65-9

1994

Arzberger T, Ritter E & Weindl A
Human facial nucleus: choline acetyltransferase and calcitonin gene-related peptide.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 1994 Dec, S403-6

Brown DR, Herms J & Kretzschmar HA
Mouse cortical cells lacking cellular PrP survive in culture with a neurotoxic PrP fragment.
Neuroreport, 1994 Oct 27, 5 (16) 2057-60

de Silva R, Ironside JW, McCardle L, Esmonde T, Bell J, Will R, Windl O, Dempster M, Estibeiro P & Lathe R
Neuropathological phenotype and 'prion protein' genotype correlation in sporadic Creutzfeldt-Jakob disease.
Neuroscience letters, 1994 Sep 26, 179 (1-2) 50-2

Kösel S, Egensperger R, Mehraein P & Graeber MB
No association of mutations at nucleotide 5460 of mitochondrial NADH dehydrogenase with Alzheimer's disease.
Biochemical and biophysical research communications, 1994 Sep 15, 203 (2) 745-9

Zurmöhle UM, Herms J, Schlingensiepen R, Schlingensiepen KH & Brysch W
Changes of synapsin I messenger RNA expression during rat brain development.
Experimental brain research, 1994, 99 (1) 17-24

Herms J, Zurmöhle U, Schlingensiepen R, Brysch W & Schlingensiepen KH
Developmental expression of the transcription factor zif268 in rat brain.
Neuroscience letters, 1994 Jan 03, 165 (1-2) 171-4

1993

Davies PT, Jahfar S, Ferguson IT & Windl O
Creutzfeldt-Jakob disease in individual occupationally exposed to BSE.
Lancet (London, England), 1993 Sep 11, 342 (8872) 680

Herms J, Zurmöhle U, Schlingensiepen KH & Brysch W
Transient expression of PKC gamma mRNA in cerebellar granule cells during rat brain development.
Neuroreport, 1993 Jul, 4 (7) 899-902

Herms J, Zurmöhle U, Brysch W & Schlingensiepen KH
Ca2+/calmodulin protein kinase and protein kinase C expression during development of rat hippocampus.
Developmental neuroscience, 1993, 15 (6) 410-6

1992

Herms J, Siebels J, Schneider M & Kuck KH
[Prospective long-term ECG study of 100 patients surviving sudden cardiac death].
Zeitschrift fur Kardiologie, 1992 Dec, 81 (12) 673-80

Weindl A, Bufler J, Winkler B, Arzberger T & Hatt H
Neurotransmitters and receptors in the subfornical organ. Immunohistochemical and electrophysiological evidence.
Progress in brain research, 1992, 91 261-9

1989

Holländer H, Egensperger R & Dirlich G
Size distribution of rhodamine-labelled microspheres retrogradely transported in cultured neurons.
Journal of neuroscience methods, 1989 Jul, 29 (1) 1-4

1988

Egensperger R & Holländer H
Electron microscopic visualization of fluorescent microspheres used as a neuronal tracer.
Journal of neuroscience methods, 1988 Apr, 23 (3) 181-6